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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (14), p.5299-5304

2012

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Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes

Nature communications, 2018-03, Vol.9 (1), p.1162-17, Article 1162

2018

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Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation

Structure (London), 2016-08, Vol.24 (8), p.1335-1345

2016

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Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A

FEBS letters, 2014-11, Vol.588 (23), p.4487-4496

2014

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Advancing Fragment Binders to Lead-Like Compounds Using Ligand and Protein-Based NMR Spectroscopy

Methods in Enzymology, 2011, Vol.493, p.469-485

Maurer, Till

2011

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USP7 small-molecule inhibitors interfere with ubiquitin binding

Nature (London), 2017-10, Vol.550 (7677), p.534-538

2017

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Structural basis for dual-mode inhibition of the ABC transporter MsbA

Nature (London), 2018-05, Vol.557 (7706), p.196-201

2018

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Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques

Journal of medicinal chemistry, 2017-12, Vol.60 (24), p.10056-10070

2017

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Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin

Scientific reports, 2016-12, Vol.6 (1), p.39374, Article 39374

2016

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Length Matters: MINDY Is a New Deubiquitinase Family that Preferentially Cleaves Long Polyubiquitin Chains

Molecular cell, 2016-07, Vol.63 (1), p.4-6

2016

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A restraint molecular dynamics and simulated annealing approach for protein homology modeling utilizing mean angles

BMC bioinformatics, 2005-04, Vol.6 (1), p.91-91

2005

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High-Resolution Structure of the Histidine-Containing Phosphocarrier Protein (HPr) from Staphylococcus aureus and Characterization of Its Interaction with the Bifunctional HPr Kinase/Phosphorylase

Journal of Bacteriology, 2004-09, Vol.186 (17), p.5906-5918

2004

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Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking

Scientific reports, 2016-10, Vol.6 (1), p.35179-35179, Article 35179

2016

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Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions

Journal of biomolecular NMR, 2007-12, Vol.39 (4), p.275-289

2007

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De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo

Journal of bacteriology, 2016-07, Vol.198 (14), p.2001-2015

2016

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Phosphorylation-dependent activity of the deubiquitinase DUBA

Nature structural & molecular biology, 2012-02, Vol.19 (2), p.171-175

2012

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Cellular uptake of a cystine‐knot peptide and modulation of its intracellular trafficking

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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NMR studies of protein-ligand interactions

Methods in molecular biology (Clifton, N.J.), 2005, Vol.305, p.197

Maurer, Till

2005

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NMR Study to Identify a Ligand-Binding Pocket in Ras

The Enzymes, 2013, Vol.33, p.15-39

2013

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Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation

Structure (London), 2016-08, Vol.24 (8)

2016

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(1)H, (13)C and (15)N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7)

Biomolecular NMR assignments, 2016-10, Vol.10 (2), p.345-349

2016

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1H, 13C and 15N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7)

Biomolecular NMR assignments, 2016-10, Vol.10 (2), p.345-349

2016

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Solution Structure of Leukemia Inhibitory Factor

The Journal of biological chemistry, 1998-05, Vol.273 (22), p.13738-13745

1998

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Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.SY23-03-SY23-03

2018

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Abstract B23: Crucial deubiquitinases in cancer cell survival

Clinical cancer research, 2017-01, Vol.23 (1_Supplement), p.B23-B23

2017

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Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes

Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation

Backbone cyclization of a recombinant cystine-knot peptide by engineered Sortase A

Advancing Fragment Binders to Lead-Like Compounds Using Ligand and Protein-Based NMR Spectroscopy

USP7 small-molecule inhibitors interfere with ubiquitin binding

Structural basis for dual-mode inhibition of the ABC transporter MsbA

Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques

Structure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin

Length Matters: MINDY Is a New Deubiquitinase Family that Preferentially Cleaves Long Polyubiquitin Chains

A restraint molecular dynamics and simulated annealing approach for protein homology modeling utilizing mean angles

High-Resolution Structure of the Histidine-Containing Phosphocarrier Protein (HPr) from Staphylococcus aureus and Characterization of Its Interaction with the Bifunctional HPr Kinase/Phosphorylase

Cellular uptake of a cystine-knot peptide and modulation of its intracellular trafficking

Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions

De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo

Phosphorylation-dependent activity of the deubiquitinase DUBA

Cellular uptake of a cystine‐knot peptide and modulation of its intracellular trafficking

NMR studies of protein-ligand interactions

NMR Study to Identify a Ligand-Binding Pocket in Ras

Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation

(1)H, (13)C and (15)N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7)

1H, 13C and 15N backbone resonance assignment for the 40.5 kDa catalytic domain of Ubiquitin Specific Protease 7 (USP7)

Solution Structure of Leukemia Inhibitory Factor

Abstract SY23-03: Development and mechanistic characterization of USP7 deubiquitinase inhibitors

Abstract B23: Crucial deubiquitinases in cancer cell survival

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