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Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

Cancer cell, 2014-08, Vol.26 (2), p.177-189

2014

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Structural Basis for the Potent and Selective Inhibition of Casein Kinase 1 Epsilon

Journal of medicinal chemistry, 2012-11, Vol.55 (22), p.10307-10311

2012

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Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Journal of medicinal chemistry, 2012-06, Vol.55 (11), p.4936-4954

2012

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Discovery of 1H‑Pyrazol-3(2H)‑ones as Potent and Selective Inhibitors of Protein Kinase R‑like Endoplasmic Reticulum Kinase (PERK)

Journal of medicinal chemistry, 2015-02, Vol.58 (3), p.1426-1441

2015

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Ordering of the N‑Terminus of Human MDM2 by Small Molecule Inhibitors

Journal of the American Chemical Society, 2012-10, Vol.134 (41), p.17059-17067

2012

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c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations

The Journal of biological chemistry, 2008-02, Vol.283 (5), p.2675-2683

2008

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Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Journal of medicinal chemistry, 2008-05, Vol.51 (10), p.2879-2882

2008

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Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay

Analytical biochemistry, 2011-12, Vol.419 (2), p.217-227

2011

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Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 resolution

Nature (London), 1998-01, Vol.391 (6664), p.251-258

1998

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Remote Density Measurements of Molten Salts via Neutron Radiography

Journal of imaging, 2021-05, Vol.7 (5), p.88

2021

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Novel 2,3-Dihydro-1,4-Benzoxazines as Potent and Orally Bioavailable Inhibitors of Tumor-Driven Angiogenesis

Journal of medicinal chemistry, 2008-03, Vol.51 (6), p.1695-1705

2008

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Demonstration of neutron time‐of‐flight diffraction with an event‐mode imaging detector

Journal of applied crystallography, 2024-08, Vol.57 (4), p.1107-1114

2024

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Flexible 3D printed silicones for gamma and neutron radiation shielding

Radiation physics and chemistry (Oxford, England : 1993), 2021-11, Vol.188, p.109616, Article 109616

2021

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Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor

Journal of medicinal chemistry, 2007-02, Vol.50 (4), p.611-626

2007

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Modulation of Ligand-Gated Glycine Receptors Via Functional Monoclonal Antibodies

The Journal of pharmacology and experimental therapeutics, 2022-10, Vol.383 (1), p.56-69

2022

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Effects of Hydrogen Redistribution at High Temperatures in Yttrium Hydride Moderator Material

JOM (1989), 2021-11, Vol.73 (11), p.3513-3518

2021

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Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2472-2488

2014

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TRINIDI: Time-of-Flight Resonance Imaging with Neutrons for Isotopic Density Inference

IEEE transactions on computational imaging, 2024-01, Vol.10, p.1-15

2024

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Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.7044-7053

2009

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Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors

Journal of medicinal chemistry, 2013-05, Vol.56 (10), p.4053-4070

2013

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Discovery of AM-7209, a Potent and Selective 4‑Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10499-10511

2014

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Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres

Journal of medicinal chemistry, 2014-04, Vol.57 (7), p.2963-2988

2014

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Development of an automated mid-scale parallel protein purification system for antibody purification and affinity chromatography

Protein expression and purification, 2016-12, Vol.128, p.29-35

2016

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Hyperspectral Neutron CT with Material Decomposition

2021 IEEE International Conference on Image Processing (ICIP), 2021, p.3482-3486

2021

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Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity

Structural Basis for the Potent and Selective Inhibition of Casein Kinase 1 Epsilon

Structure-Based Design of Novel Inhibitors of the MDM2–p53 Interaction

Discovery of 1H‑Pyrazol-3(2H)‑ones as Potent and Selective Inhibitors of Protein Kinase R‑like Endoplasmic Reticulum Kinase (PERK)

Ordering of the N‑Terminus of Human MDM2 by Small Molecule Inhibitors

c-Met Inhibitors with Novel Binding Mode Show Activity against Several Hereditary Papillary Renal Cell Carcinoma-related Mutations

Discovery and Optimization of Triazolopyridazines as Potent and Selective Inhibitors of the c-Met Kinase

Screening for lysine-specific demethylase-1 inhibitors using a label-free high-throughput mass spectrometry assay

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 resolution

Remote Density Measurements of Molten Salts via Neutron Radiography

Novel 2,3-Dihydro-1,4-Benzoxazines as Potent and Orally Bioavailable Inhibitors of Tumor-Driven Angiogenesis

Demonstration of neutron time‐of‐flight diffraction with an event‐mode imaging detector

Flexible 3D printed silicones for gamma and neutron radiation shielding

Evolution of a Highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor

Modulation of Ligand-Gated Glycine Receptors Via Functional Monoclonal Antibodies

Effects of Hydrogen Redistribution at High Temperatures in Yttrium Hydride Moderator Material

Selective and Potent Morpholinone Inhibitors of the MDM2–p53 Protein–Protein Interaction

TRINIDI: Time-of-Flight Resonance Imaging with Neutrons for Isotopic Density Inference

The Complex, Unique, and Powerful Imaging Instrument for Dynamics (CUPI2D) at the Spallation Neutron Source (invited)

Discovery and Optimization of Chromenotriazolopyrimidines as Potent Inhibitors of the Mouse Double Minute 2−Tumor Protein 53 Protein−Protein Interaction

Rational Design and Binding Mode Duality of MDM2–p53 Inhibitors

Discovery of AM-7209, a Potent and Selective 4‑Amidobenzoic Acid Inhibitor of the MDM2–p53 Interaction

Novel Inhibitors of the MDM2-p53 Interaction Featuring Hydrogen Bond Acceptors as Carboxylic Acid Isosteres

Development of an automated mid-scale parallel protein purification system for antibody purification and affinity chromatography

Hyperspectral Neutron CT with Material Decomposition

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