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ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma

Nature communications, 2024-06, Vol.15 (1), p.5294-22, Article 5294

2024

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REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15799

2023

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Selective Inhibition of DNA Polymerase β by a Covalent Inhibitor

Journal of the American Chemical Society, 2021-06, Vol.143 (21), p.8099-8107

2021

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ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining

Nucleic acids research, 2023-07, Vol.51 (13), p.6770-6783

2023

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Expanded Substrate Scope of DNA Polymerase θ and DNA Polymerase β: Lyase Activity on 5′-Overhangs and Clustered Lesions

Biochemistry (Easton), 2018-10, Vol.57 (42), p.6119-6127

2018

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Correction to "Selective Inhibition of DNA Polymerase β by a Covalent Inhibitor"

Journal of the American Chemical Society, 2022-02, Vol.144 (6), p.2825-2825

2022

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Mechanistic Insight through Irreversible Inhibition: DNA Polymerase θ Uses a Common Active Site for Polymerase and Lyase Activities

Journal of the American Chemical Society, 2018-07, Vol.140 (29), p.9034-9037

2018

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In Vitro Bypass of Thymidine Glycol by DNA Polymerase θ Forms Sequence-Dependent Frameshift Mutations

Biochemistry (Easton), 2017-12, Vol.56 (51), p.6726-6733

2017

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Automated quantification of budding Saccharomyces cerevisiae using a novel image cytometry method

Journal of industrial microbiology & biotechnology, 2013-06, Vol.40 (6), p.581-588

2013

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Morphological observation and analysis using automated image cytometry for the comparison of trypan blue and fluorescence-based viability detection method

Cytotechnology (Dordrecht), 2015-05, Vol.67 (3), p.461-473

2015

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An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation

Progress in biophysics and molecular biology, 2021-08, Vol.163, p.143-159

2021

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CDK-independent role of D-type cyclins in regulating DNA mismatch repair

Molecular cell, 2024-04, Vol.84 (7), p.1224-1242.e13

2024

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Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

Science translational medicine, 2024-02, Vol.16 (734), p.eadj5962

2024

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The A‑Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ

ACS chemical biology, 2017-06, Vol.12 (6), p.1584-1592

2017

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Accurate measurement of peripheral blood mononuclear cell concentration using image cytometry to eliminate RBC-induced counting error

Journal of immunological methods, 2013-02, Vol.388 (1-2), p.25-32

2013

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Abstract 2598: AZD1390 radio-sensitizes p53-mutant GBM via disrupting homology directed DNA repair

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.2598-2598

2022

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Assessing the ecological impacts of invasive species based on their functional responses and abundances

Biological invasions, 2017-05, Vol.19 (5), p.1653-1665

2017

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potential of cytokines as safety biomarkers for drug-induced liver injury

European journal of clinical pharmacology, 2010-10, Vol.66 (10), p.961-976

2010

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The impact of the COVID-19 pandemic upon pancreatic cancer treatment (CONTACT Study): a UK national observational cohort study

British journal of cancer, 2023-05, Vol.128 (10), p.1922-1932

2023

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The Young Everest Study: preliminary report of changes in sleep and cerebral blood flow velocity during slow ascent to altitude in unacclimatised children

Archives of disease in childhood, 2013-05, Vol.98 (5), p.356-362

2013

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Wheezing Symptoms and Parental Asthma Are Associated with a Physician Diagnosis of Asthma in Children with Sickle Cell Anemia

The Journal of pediatrics, 2014-04, Vol.164 (4), p.821-826.e1

2014

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Cidofovir in addition to antiretroviral treatment is not effective for AIDS-associated progressive multifocal leukoencephalopathy : a multicohort analysis

AIDS (London), 2008-09, Vol.22 (14), p.1759-1767

2008

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Immunogenicity, Immunologic Memory, and Safety Following Measles Revaccination in HIV-Infected Children Receiving Highly Active Antiretroviral Therapy

The Journal of infectious diseases, 2012-08, Vol.206 (4), p.512-522

2012

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ATM inhibition exploits checkpoint defects and ATM-dependent double strand break repair in TP53-mutant glioblastoma

REV7 Monomer Is Unable to Participate in Double Strand Break Repair and Translesion Synthesis but Suppresses Mitotic Errors

Selective Inhibition of DNA Polymerase β by a Covalent Inhibitor

ATM phosphorylates the FATC domain of DNA-PKcs at threonine 4102 to promote non-homologous end joining

Expanded Substrate Scope of DNA Polymerase θ and DNA Polymerase β: Lyase Activity on 5′-Overhangs and Clustered Lesions

Correction to "Selective Inhibition of DNA Polymerase β by a Covalent Inhibitor"

Mechanistic Insight through Irreversible Inhibition: DNA Polymerase θ Uses a Common Active Site for Polymerase and Lyase Activities

In Vitro Bypass of Thymidine Glycol by DNA Polymerase θ Forms Sequence-Dependent Frameshift Mutations

Automated quantification of budding Saccharomyces cerevisiae using a novel image cytometry method

Morphological observation and analysis using automated image cytometry for the comparison of trypan blue and fluorescence-based viability detection method

An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation

CDK-independent role of D-type cyclins in regulating DNA mismatch repair

Aberrant ATM signaling and homology-directed DNA repair as a vulnerability of p53-mutant GBM to AZD1390-mediated radiosensitization

DNA-PK inhibition shows differential radiosensitization in orthotopic GBM PDX models based on DDR pathway deficits

The A‑Rule and Deletion Formation During Abasic and Oxidized Abasic Site Bypass by DNA Polymerase θ

Accurate measurement of peripheral blood mononuclear cell concentration using image cytometry to eliminate RBC-induced counting error

Abstract 2598: AZD1390 radio-sensitizes p53-mutant GBM via disrupting homology directed DNA repair

Invader Relative Impact Potential: a new metric to understand and predict the ecological impacts of existing, emerging and future invasive alien species

Assessing the ecological impacts of invasive species based on their functional responses and abundances

potential of cytokines as safety biomarkers for drug-induced liver injury

The impact of the COVID-19 pandemic upon pancreatic cancer treatment (CONTACT Study): a UK national observational cohort study

The Young Everest Study: preliminary report of changes in sleep and cerebral blood flow velocity during slow ascent to altitude in unacclimatised children

Wheezing Symptoms and Parental Asthma Are Associated with a Physician Diagnosis of Asthma in Children with Sickle Cell Anemia

Cidofovir in addition to antiretroviral treatment is not effective for AIDS-associated progressive multifocal leukoencephalopathy : a multicohort analysis

Immunogenicity, Immunologic Memory, and Safety Following Measles Revaccination in HIV-Infected Children Receiving Highly Active Antiretroviral Therapy

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