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The genetic landscape of the human solute carrier (SLC) transporter superfamily

Human genetics, 2019-12, Vol.138 (11-12), p.1359-1377

2019

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The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity

International journal of molecular sciences, 2016-10, Vol.17 (10), p.1714-1714

2016

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Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

The AAPS journal, 2017-11, Vol.20 (1), p.4-4, Article 4

2017

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Genetic variation in the human cytochrome P450 supergene family

Pharmacogenetics and genomics, 2015-12, Vol.25 (12), p.584-594

2015

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Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

Pharmacology & therapeutics (Oxford), 2019-05, Vol.197, p.122-152

2019

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3D human liver spheroids for translational pharmacology and toxicology

Basic & clinical pharmacology & toxicology, 2022-01, Vol.130 (S1), p.5-15

2022

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Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

Toxicological sciences, 2018-06, Vol.163 (2), p.655-665

2018

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An optimized prediction framework to assess the functional impact of pharmacogenetic variants

The pharmacogenomics journal, 2019-04, Vol.19 (2), p.115-126

2019

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Integrating rare genetic variants into pharmacogenetic drug response predictions

Human genomics, 2018-05, Vol.12 (1), p.26-12, Article 26

2018

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Towards more accurate pharmacogenomic variant effect predictions

Pharmacogenomics, 2023-11, Vol.24 (16), p.841-844

2023

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Human hepatic 3D spheroids as a model for steatosis and insulin resistance

Scientific reports, 2018-09, Vol.8 (1), p.14297-12, Article 14297

2018

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Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

Cell, 2018-02, Vol.172 (5), p.1079-1090.e12

2018

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Scaling of embryonic patterning based on phase―gradient encoding

Nature (London), 2013-01, Vol.493 (7430), p.101-105

2013

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Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

The FASEB journal, 2017-06, Vol.31 (6), p.2696-2708

2017

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How to Consider Rare Genetic Variants in Personalized Drug Therapy

Clinical pharmacology and therapeutics, 2018-05, Vol.103 (5), p.745-748

2018

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In vitro and ex vivo models of adipocytes

American Journal of Physiology: Cell Physiology, 2021-05, Vol.320 (5), p.C822-C841

2021

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Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection

EMBO molecular medicine, 2021-01, Vol.13 (1), p.e13426-n/a

2021

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Global distribution of functionally important CYP2C9 alleles and their inferred metabolic consequences

Human genomics, 2023-02, Vol.17 (1), p.15-15, Article 15

2023

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Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

Genetics in medicine, 2018-06, Vol.20 (6), p.622-629

2018

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Can CYP Inhibition Overcome Chemotherapy Resistance?

Trends in pharmacological sciences (Regular ed.), 2020-08, Vol.41 (8), p.503-506

2020

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Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing

Clinical pharmacology and therapeutics, 2019-10, Vol.106 (4), p.866-873

2019

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Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury

Frontiers in pharmacology, 2019-09, Vol.10, p.1093

2019

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The role of microRNAs in liver injury at the crossroad between hepatic cell death and regeneration

Biochemical and biophysical research communications, 2017-01, Vol.482 (3), p.399-407

2017

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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data

Frontiers in pharmacology, 2018-12, Vol.9, p.1437-1437

2018

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Single Cell Atlas: a single-cell multi-omics human cell encyclopedia

Genome Biology, 2024-04, Vol.25 (1), p.104-21, Article 104

2024

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The genetic landscape of the human solute carrier (SLC) transporter superfamily

The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

Genetic variation in the human cytochrome P450 supergene family

Novel genetic and epigenetic factors of importance for inter-individual differences in drug disposition, response and toxicity

3D human liver spheroids for translational pharmacology and toxicology

Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

An optimized prediction framework to assess the functional impact of pharmacogenetic variants

Integrating rare genetic variants into pharmacogenetic drug response predictions

Towards more accurate pharmacogenomic variant effect predictions

Human hepatic 3D spheroids as a model for steatosis and insulin resistance

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

Scaling of embryonic patterning based on phase―gradient encoding

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

How to Consider Rare Genetic Variants in Personalized Drug Therapy

In vitro and ex vivo models of adipocytes

Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection

Global distribution of functionally important CYP2C9 alleles and their inferred metabolic consequences

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

Can CYP Inhibition Overcome Chemotherapy Resistance?

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing

Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury

The role of microRNAs in liver injury at the crossroad between hepatic cell death and regeneration

Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data

Single Cell Atlas: a single-cell multi-omics human cell encyclopedia

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