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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

The lancet oncology, 2021-10, Vol.22 (10), p.e456-e465

2021

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Bayesian optimization with adaptive surrogate models for automated experimental design

npj computational materials, 2021-12, Vol.7 (1), p.1-12, Article 194

2021

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Synergistic Coupling of Histone H3 Phosphorylation and Acetylation in Response to Epidermal Growth Factor Stimulation

Molecular cell, 2000-06, Vol.5 (6), p.905-915

2000

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Silent Information Regulator 2 Family of NAD-Dependent Histone/Protein Deacetylases Generates a Unique Product, 1-O-Acetyl-ADP-Ribose

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14178-14182

2000

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Specific and Reversible Inactivation of Protein Tyrosine Phosphatases by Hydrogen Peroxide: Evidence for a Sulfenic Acid Intermediate and Implications for Redox Regulation

Biochemistry (Easton), 1998-04, Vol.37 (16), p.5633-5642

1998

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The future of cancer immunotherapy for brain tumors: a collaborative workshop

Journal of translational medicine, 2022-05, Vol.20 (1), p.236-236, Article 236

2022

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Accelerated design of Fe-based soft magnetic materials using machine learning and stochastic optimization

Acta materialia, 2020-08, Vol.194, p.144-155

2020

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Towards stacking fault energy engineering in FCC high entropy alloys

Acta materialia, 2022-02, Vol.224, p.117472, Article 117472

2022

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Entropy-driven melting point depression in fcc HEAs

Scripta materialia, 2021-10, Vol.208

2021

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Entropy-driven melting point depression in fcc HEAs

Scripta materialia, 2022-02, Vol.208 (C), p.114336, Article 114336

2022

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High-throughput exploration of the WMoVTaNbAl refractory multi-principal-element alloys under multiple-property constraints

Acta materialia, 2023-04, Vol.248, p.118784, Article 118784

2023

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Kinetic Mechanism of Human Histone Acetyltransferase P/CAF

Biochemistry (Easton), 2000-10, Vol.39 (39), p.11961-11969

2000

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[29] Redox regulation of protein tyrosine phosphatases by hydrogen peroxide: Detecting sulfenic acid intermediates and examining reversible inactivation

Methods in Enzymology, 2002, Vol.348, p.297-305

2002

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Understanding the effect of refractory metal chemistry on the stacking fault energy and mechanical property of Cantor-based multi-principal element alloys

International journal of plasticity, 2024-08, Vol.179, p.104020, Article 104020

2024

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The Acetyltransferase Activity of CBP Is Required for wingless Activation and H4 Acetylation in Drosophila melanogaster

Molecular and Cellular Biology, 2002-06, Vol.22 (11), p.3832-3841

2002

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Pseudoelastic deformation in Mo-based refractory multi-principal element alloys

Acta materialia, 2021-11, Vol.220, p.117299, Article 117299

2021

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Towards stacking fault energy engineering in FCC high entropy alloys

Acta materialia, 2021-11, Vol.224

2021

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Catalytic Mechanism and Function of Invariant Glutamic Acid 173 from the Histone Acetyltransferase GCN5 Transcriptional Coactivator

The Journal of biological chemistry, 1999-06, Vol.274 (26), p.18157-18160

1999

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Kinetic Mechanism of the Histone Acetyltransferase GCN5 from Yeast

The Journal of biological chemistry, 2000-07, Vol.275 (29), p.22048-22055

2000

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Dimerization of the Extracellular Domain of the Receptor for Epidermal Growth Factor Containing the Membrane-spanning Segment in Response to Treatment with Epidermal Growth Factor

The Journal of biological chemistry, 1999-12, Vol.274 (50), p.35985-35990

1999

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Accelerating glioblastoma therapeutics via venture philanthropy

Drug discovery today, 2021-07, Vol.26 (7), p.1744-1749

2021

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GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.TPS2078-TPS2078

2022

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CTNI-85. GBM AGILE PLATFORM TRIAL FOR NEWLY DIAGNOSED AND RECURRENT GBM: RESULTS OF FIRST EXPERIMENTAL ARM, REGORAFENIB

Neuro-oncology (Charlottesville, Va.), 2023-11, Vol.25 (Supplement_5), p.v97-v98

2023

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GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.TPS2074-TPS2074

2021

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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

Bayesian optimization with adaptive surrogate models for automated experimental design

Synergistic Coupling of Histone H3 Phosphorylation and Acetylation in Response to Epidermal Growth Factor Stimulation

Silent Information Regulator 2 Family of NAD-Dependent Histone/Protein Deacetylases Generates a Unique Product, 1-O-Acetyl-ADP-Ribose

Specific and Reversible Inactivation of Protein Tyrosine Phosphatases by Hydrogen Peroxide: Evidence for a Sulfenic Acid Intermediate and Implications for Redox Regulation

The future of cancer immunotherapy for brain tumors: a collaborative workshop

Accelerated design of Fe-based soft magnetic materials using machine learning and stochastic optimization

Towards stacking fault energy engineering in FCC high entropy alloys

Entropy-driven melting point depression in fcc HEAs

Entropy-driven melting point depression in fcc HEAs

High-throughput exploration of the WMoVTaNbAl refractory multi-principal-element alloys under multiple-property constraints

Kinetic Mechanism of Human Histone Acetyltransferase P/CAF

[29] Redox regulation of protein tyrosine phosphatases by hydrogen peroxide: Detecting sulfenic acid intermediates and examining reversible inactivation

Understanding the effect of refractory metal chemistry on the stacking fault energy and mechanical property of Cantor-based multi-principal element alloys

The Acetyltransferase Activity of CBP Is Required for wingless Activation and H4 Acetylation in Drosophila melanogaster

Pseudoelastic deformation in Mo-based refractory multi-principal element alloys

Towards stacking fault energy engineering in FCC high entropy alloys

Catalytic Mechanism and Function of Invariant Glutamic Acid 173 from the Histone Acetyltransferase GCN5 Transcriptional Coactivator

Kinetic Mechanism of the Histone Acetyltransferase GCN5 from Yeast

Dimerization of the Extracellular Domain of the Receptor for Epidermal Growth Factor Containing the Membrane-spanning Segment in Response to Treatment with Epidermal Growth Factor

Accelerating glioblastoma therapeutics via venture philanthropy

Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

CTNI-85. GBM AGILE PLATFORM TRIAL FOR NEWLY DIAGNOSED AND RECURRENT GBM: RESULTS OF FIRST EXPERIMENTAL ARM, REGORAFENIB

GBM AGILE: A global, phase 2/3 adaptive platform trial to evaluate multiple regimens in newly diagnosed and recurrent glioblastoma

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