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Design of structurally distinct proteins using strategies inspired by evolution

Science (American Association for the Advancement of Science), 2016-05, Vol.352 (6286), p.687-690

2016

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Engineering and Application of LOV2-Based Photoswitches

Methods in enzymology, 2016, Vol.580, p.169-190

2016

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Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies

Protein science, 2017-10, Vol.26 (10), p.2021-2038

2017

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Adaptation to high salinity in poplar involves changes in xylem anatomy and auxin physiology

Plant, cell and environment, 2006-08, Vol.29 (8), p.1519-1531

2006

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Comics of the New Europe: Reflections and Intersections

2023

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Computer-based redesign of a protein folding pathway

Nature structural & molecular biology, 2001-07, Vol.8 (7), p.602-605

2001

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Coenzyme Q10 Supplementation in Statin Treated Patients: A Double-Blinded Randomized Placebo-Controlled Trial

Antioxidants, 2022-08, Vol.11 (9), p.1698

2022

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The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate‐intensity exercise in human skeletal muscle

The Journal of physiology, 2016-04, Vol.594 (8), p.2339-2358

2016

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A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins

Protein engineering, design and selection, 2013-04, Vol.26 (4), p.283-289

2013

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RosettaDesign server for protein design

Nucleic acids research, 2006-07, Vol.34 (Web Server issue), p.W235

2006

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The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

Applied physiology, nutrition, and metabolism, 2021-09, Vol.46 (9), p.1133

2021

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Glucose homeostasis in statin users—The LIFESTAT study

Diabetes/metabolism research and reviews, 2019-03, Vol.35 (3), p.e3110-n/a

2019

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Native Protein Sequences Are Close to Optimal for Their Structures

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (19), p.10383-10388

2000

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Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon

Molecular cell, 2016-03, Vol.61 (6), p.809-820

2016

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Computational Design of a Single Amino Acid Sequence that Can Switch between Two Distinct Protein Folds

Journal of the American Chemical Society, 2006-02, Vol.128 (4), p.1154-1161

2006

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Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

Science (American Association for the Advancement of Science), 2003-11, Vol.302 (5649), p.1364-1368

2003

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A Large Scale Test of Computational Protein Design: Folding and Stability of Nine Completely Redesigned Globular Proteins

Journal of molecular biology, 2003-09, Vol.332 (2), p.449-460

2003

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Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation

Cytokine (Philadelphia, Pa.), 2019-01, Vol.113, p.393-399

2019

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High-resolution design of a protein loop

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (45), p.17668-17673

2007

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Protein–Protein Docking with Simultaneous Optimization of Rigid-body Displacement and Side-chain Conformations

Journal of molecular biology, 2003-08, Vol.331 (1), p.281-299

2003

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Exploring folding free energy landscapes using computational protein design

Current opinion in structural biology, 2004-02, Vol.14 (1), p.89-95

2004

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Effects of once-weekly semaglutide on major adverse cardiovascular events in patients with type 2 diabetes and polyvascular disease: a post hoc analysis of the SUSTAIN 6 trial

European heart journal, 2023-11, Vol.44 (Supplement_2)

2023

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Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design

Structure (London), 2008-12, Vol.16 (12), p.1799-1805

2008

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E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

Nature structural & molecular biology, 2005-10, Vol.12 (10), p.933-934

2005

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Semaglutide Improves eGFR Slope vs. Placebo Regardless of Baseline HbA1c and Blood Pressure in People With Type 2 Diabetes: A Post Hoc Analysis of SUSTAIN 6 and PIONEER 6: SA-PO265

Journal of the American Society of Nephrology, 2022-11, Vol.33 (11S), p.675-675

2022

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Design of structurally distinct proteins using strategies inspired by evolution

Engineering and Application of LOV2-Based Photoswitches

Computational design of a specific heavy chain/κ light chain interface for expressing fully IgG bispecific antibodies

Adaptation to high salinity in poplar involves changes in xylem anatomy and auxin physiology

Comics of the New Europe: Reflections and Intersections

Computer-based redesign of a protein folding pathway

Coenzyme Q10 Supplementation in Statin Treated Patients: A Double-Blinded Randomized Placebo-Controlled Trial

The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate‐intensity exercise in human skeletal muscle

A structural bioinformatics approach for identifying proteins predisposed to bind linear epitopes on pre-selected target proteins

RosettaDesign server for protein design

The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

Glucose homeostasis in statin users—The LIFESTAT study

Native Protein Sequences Are Close to Optimal for Their Structures

Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon

Computational Design of a Single Amino Acid Sequence that Can Switch between Two Distinct Protein Folds

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

A Large Scale Test of Computational Protein Design: Folding and Stability of Nine Completely Redesigned Globular Proteins

Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation

High-resolution design of a protein loop

Protein–Protein Docking with Simultaneous Optimization of Rigid-body Displacement and Side-chain Conformations

Exploring folding free energy landscapes using computational protein design

Effects of once-weekly semaglutide on major adverse cardiovascular events in patients with type 2 diabetes and polyvascular disease: a post hoc analysis of the SUSTAIN 6 trial

Computer-Based Redesign of a β Sandwich Protein Suggests that Extensive Negative Design Is Not Required for De Novo β Sheet Design

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

Semaglutide Improves eGFR Slope vs. Placebo Regardless of Baseline HbA1c and Blood Pressure in People With Type 2 Diabetes: A Post Hoc Analysis of SUSTAIN 6 and PIONEER 6: SA-PO265

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