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Molecular mechanisms of thalidomide and its derivatives

Proceedings of the Japan Academy, Series B, 2020/06/11, Vol.96(6), pp.189-203

2020

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Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

Nature communications, 2020-02, Vol.11 (1), p.1004-1004, Article 1004

2020

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Cereblon and its downstream substrates as molecular targets of immunomodulatory drugs

International Journal of Hematology, 2016-09, Vol.104 (3), p.293-299

2016

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Molecular Mechanisms of the Teratogenic Effects of Thalidomide

Pharmaceuticals (Basel, Switzerland), 2020-05, Vol.13 (5), p.95

2020

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Multi-phaseted problems of TDP-43 in selective neuronal vulnerability in ALS

Cellular and molecular life sciences : CMLS, 2021-05, Vol.78 (10), p.4453-4465

2021

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Identification of a Primary Target of Thalidomide Teratogenicity

Science (American Association for the Advancement of Science), 2010-03, Vol.327 (5971), p.1345-1350

2010

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Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders

Chemical Society reviews, 2022-08, Vol.51 (15), p.6234-625

2022

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Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology

Cell chemical biology, 2021-07, Vol.28 (7), p.987-999

2021

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p63 is a cereblon substrate involved in thalidomide teratogenicity

Nature chemical biology, 2019-11, Vol.15 (11), p.1077

2019

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Exhaled breath analysis for lung cancer detection using ion mobility spectrometry

PloS one, 2014-12, Vol.9 (12), p.e114555-e114555

2014

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Evaluation of airway involvement and treatment in patients with relapsing polychondritis

Scientific reports, 2023-05, Vol.13 (1), p.8307-8307, Article 8307

2023

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Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs

Nature structural & molecular biology, 2014-09, Vol.21 (9), p.803

2014

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The Role and Function of microRNA in the Pathogenesis of Multiple Myeloma

Cancers, 2019-11, Vol.11 (11), p.1738

2019

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Treatment pattern and clinical outcomes in multiple myeloma patients in Japan using the Medical Data Vision claims database

PloS one, 2023-04, Vol.18 (4), p.e0283931

2023

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Treatment pattern and clinical outcomes in multiple myeloma patients in Japan using the Medical Data Vision claims database

PloS one, 2023-04, Vol.18 (4), p.e0283931-e0283931

2023

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Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond

Biochimica et biophysica acta, 2013-01, Vol.1829 (1), p.98-104

2013

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A Quantitative Computed Tomography Analysis of Fissure Integrity and Emphysema Destruction in Japanese Patients with Severe Chronic Obstructive Pulmonary Disease

Internal Medicine, 2024, pp.2250-23

2024

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Application of high-performance magnetic nanobeads to biological sensing devices

Analytical and bioanalytical chemistry, 2019-03, Vol.411 (9), p.1825-1837

2019

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Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Nature communications, 2016-03, Vol.7 (1), p.11030-11030, Article 11030

2016

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Teratogenic effects of thalidomide: molecular mechanisms

Cellular and molecular life sciences : CMLS, 2011-05, Vol.68 (9), p.1569-1579

2011

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Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera

Clinical chemistry (Baltimore, Md.), 2018-10, Vol.64 (10), p.1463-1473

2018

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Pre-treatment bronchoscopic evaluation in a case of relapsing polychondrits

BMC pulmonary medicine, 2023-04, Vol.23 (1), p.108-108, Article 108

2023

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Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae

Journal of visualized experiments, 2022-02 (180)

2022

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DNA damage‐induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation

Cell proliferation, 2023-06, Vol.56 (6), p.e13398-n/a

2023

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Molecular mechanisms of thalidomide and its derivatives

Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons

Cereblon and its downstream substrates as molecular targets of immunomodulatory drugs

Molecular Mechanisms of the Teratogenic Effects of Thalidomide

Multi-phaseted problems of TDP-43 in selective neuronal vulnerability in ALS

Identification of a Primary Target of Thalidomide Teratogenicity

Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders

Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology

p63 is a cereblon substrate involved in thalidomide teratogenicity

Exhaled breath analysis for lung cancer detection using ion mobility spectrometry

Evaluation of airway involvement and treatment in patients with relapsing polychondritis

Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs

The Role and Function of microRNA in the Pathogenesis of Multiple Myeloma

Treatment pattern and clinical outcomes in multiple myeloma patients in Japan using the Medical Data Vision claims database

Treatment pattern and clinical outcomes in multiple myeloma patients in Japan using the Medical Data Vision claims database

Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond

Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma

A Quantitative Computed Tomography Analysis of Fissure Integrity and Emphysema Destruction in Japanese Patients with Severe Chronic Obstructive Pulmonary Disease

Application of high-performance magnetic nanobeads to biological sensing devices

Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

Teratogenic effects of thalidomide: molecular mechanisms

Development of a Highly Sensitive Device for Counting the Number of Disease-Specific Exosomes in Human Sera

Pre-treatment bronchoscopic evaluation in a case of relapsing polychondrits

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae

DNA damage‐induced cellular senescence is regulated by 53BP1 accumulation in the nuclear foci and phase separation

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