UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment

Journal of internal medicine, 2024-05, Vol.295 (5), p.583-598

2024

Volltextzugriff (PDF)

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database

Clinical pharmacology and therapeutics, 2018-03, Vol.103 (3), p.399-401

2018

Volltextzugriff (PDF)

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

The FASEB journal, 2017-06, Vol.31 (6), p.2696-2708

2017

Volltextzugriff (PDF)

3D human liver spheroids for translational pharmacology and toxicology

Basic & clinical pharmacology & toxicology, 2022-01, Vol.130 (S1), p.5-15

2022

Volltextzugriff (PDF)

How to Consider Rare Genetic Variants in Personalized Drug Therapy

Clinical pharmacology and therapeutics, 2018-05, Vol.103 (5), p.745-748

2018

Volltextzugriff (PDF)

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing

Clinical pharmacology and therapeutics, 2019-10, Vol.106 (4), p.866-873

2019

Volltextzugriff (PDF)

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes

Clinical pharmacology and therapeutics, 2020-10, Vol.108 (4), p.844-855

2020

Volltextzugriff (PDF)

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1743-1756

2016

Volltextzugriff (PDF)

Pharmacogenomic Prescribing Guidelines: Are They Always Useful?

Clinical pharmacology and therapeutics, 2024-10, Vol.116 (4), p.899-901

Ingelman-Sundberg, Magnus

2024

Volltextzugriff (PDF)

Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism

Archives of toxicology, 2021-01, Vol.95 (1), p.11-25

2021

Volltextzugriff (PDF)

Stem cell–derived models to improve mechanistic understanding and prediction of human drug‐induced liver injury

Hepatology (Baltimore, Md.), 2017-02, Vol.65 (2), p.710-721

2017

Volltextzugriff (PDF)

Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

Clinical and translational science, 2022-09, Vol.15 (9), p.2135-2145

2022

Volltextzugriff (PDF)

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

Archives of toxicology, 2016-12, Vol.90 (12), p.2979-3003

2016

Volltextzugriff (PDF)

A 3D Cell Culture Model Identifies Wnt/β‐Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration

Advanced science, 2020-08, Vol.7 (15), p.2000248-n/a

2020

Volltextzugriff (PDF)

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials

European neuropsychopharmacology, 2024-04, Vol.81, p.43-52

2024

Volltextzugriff (PDF)

CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload

International journal of molecular sciences, 2021-08, Vol.22 (15), p.8221

2021

Volltextzugriff (PDF)

The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia

Neuropathology and applied neurobiology, 2023-02, Vol.49 (1), p.e12867-n/a

2023

Volltextzugriff (PDF)

Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine

Clinical and translational science, 2024-02, Vol.17 (2), p.e13743-n/a

2024

Volltextzugriff (PDF)

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients

The American journal of psychiatry, 2018-05, Vol.175 (5), p.463-470

2018

Volltextzugriff (PDF)

Increased omeprazole metabolism in carriers of the CYP2C1917 allele; a pharmacokinetic study in healthy volunteers

British journal of clinical pharmacology, 2008-05, Vol.65 (5), p.767-774

2008

Volltextzugriff (PDF)

Evaluation of Current Regulation and Guidelines of Pharmacogenomic Drug Labels: Opportunities for Improvements

Clinical pharmacology and therapeutics, 2020-05, Vol.107 (5), p.1240-1255

2020

Volltextzugriff (PDF)

Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits

Clinical and translational science, 2023-01, Vol.16 (1), p.62-72

2023

Volltextzugriff (PDF)

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response

British journal of clinical pharmacology, 2024-03

2024

Volltextzugriff (PDF)

Genetic variation in the human cytochrome P450 supergene family

Pharmacogenetics and genomics, 2015-12, Vol.25 (12), p.584-594

2015

Volltextzugriff (PDF)

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

The AAPS journal, 2017-11, Vol.20 (1), p.4-4, Article 4

2017

Volltextzugriff (PDF)

1 – 25 von 552

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(511)
Mit Volltextzugriff
(423)

Publikationsform

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(417)
Life Sciences & Biomedicine
(405)
Medicin Och Hälsovetenskap
(364)
Humans
(285)
Animals
(187)
Pharmacology & Pharmacy
(177)
Biological And Medical Sciences
(145)
Male
(144)
Rats
(108)
Biochemistry & Molecular Biology
(103)
Medical Sciences
(102)
Cytochrome P-450 Enzyme System - Metabolism
(91)
Cytochrome P-450 Enzyme System - Genetics
(78)
Female
(76)
Cytochrome P450
(75)
Toxicology
(67)
Genotype
(55)
Microsomes, Liver - Enzymology
(53)
Polymorphism, Genetic
(53)
Alleles
(51)

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(5)

Menü

Weitere Dienste

Einstellungen

Precision medicine in cardiovascular therapeutics: Evaluating the role of pharmacogenetic analysis prior to drug treatment

The Pharmacogene Variation (PharmVar) Consortium: Incorporation of the Human Cytochrome P450 (CYP) Allele Nomenclature Database

Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long‐term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomics

3D human liver spheroids for translational pharmacology and toxicology

How to Consider Rare Genetic Variants in Personalized Drug Therapy

Development of the PGx‐Passport: A Panel of Actionable Germline Genetic Variants for Pre‐Emptive Pharmacogenetic Testing

Clinically Relevant Cytochrome P450 3A4 Induction Mechanisms and Drug Screening in Three‐Dimensional Spheroid Cultures of Primary Human Hepatocytes

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Pharmacogenomic Prescribing Guidelines: Are They Always Useful?

Transcriptional and post-transcriptional regulation of the pregnane X receptor: a rationale for interindividual variability in drug metabolism

Stem cell–derived models to improve mechanistic understanding and prediction of human drug‐induced liver injury

Impact of the novel CYP2C:TG haplotype and CYP2B6 variants on sertraline exposure in a large patient population

Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man

A 3D Cell Culture Model Identifies Wnt/β‐Catenin Mediated Inhibition of p53 as a Critical Step during Human Hepatocyte Regeneration

Current level of evidence for improvement of antidepressant efficacy and tolerability by pharmacogenomic-guided treatment: A Systematic review and meta-analysis of randomized controlled clinical trials

CYP2E1 in Alcoholic and Non-Alcoholic Liver Injury. Roles of ROS, Reactive Intermediates and Lipid Overload

The humanised CYP2C19 transgenic mouse exhibits cerebellar atrophy and movement impairment reminiscent of ataxia

Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients

Increased omeprazole metabolism in carriers of the CYP2C1917 allele; a pharmacokinetic study in healthy volunteers

Evaluation of Current Regulation and Guidelines of Pharmacogenomic Drug Labels: Opportunities for Improvements

Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response

Genetic variation in the human cytochrome P450 supergene family

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

Suchergebnisse filtern