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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (39), p.15644-15649

2013

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Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Nature materials, 2021-02, Vol.20 (2), p.260-271

2021

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Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas

Molecular cell, 2019-06, Vol.74 (5), p.936-950.e5

2019

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Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines

Development (Cambridge), 2019-01, Vol.146 (1)

2019

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Evaluation of variability in human kidney organoids

Nature methods, 2019-01, Vol.16 (1), p.79-87

2019

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Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms

American journal of human genetics, 2018-05, Vol.102 (5), p.816-831

2018

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Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

Cell stem cell, 2021-04, Vol.28 (4), p.671-684.e6

2021

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Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

Stem cell reports, 2018-03, Vol.10 (3), p.751-765

2018

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Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids

Nature communications, 2022-10, Vol.13 (1), p.5943-23, Article 5943

2022

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Optic Vesicle‐like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment

Stem cells (Dayton, Ohio), 2011-08, Vol.29 (8), p.1206-1218

2011

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A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

Stem cell reports, 2016-09, Vol.7 (3), p.508-517

2016

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Kidney Organoids Generated Using an Allelic Series of NPHS2 Point Variants Reveal Distinct Intracellular Podocin Mistrafficking

Journal of the American Society of Nephrology, 2023-01, Vol.34 (1), p.88-109

2023

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Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

Stem cell reports, 2015-12, Vol.5 (6), p.1109-1118

2015

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DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets

Genome medicine, 2022-02, Vol.14 (1), p.19-19, Article 19

2022

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Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (16), p.6537-6542

2011

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Phosphorylation regulates human OCT4

Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (19), p.7162-7168

2012

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Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9

International journal of molecular sciences, 2018-12, Vol.19 (12), p.4127

2018

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Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1

Kidney international, 2019-05, Vol.95 (5), p.1153-1166

2019

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Generation of heterozygous (MCRIi031-A-1) and homozygous (MCRIi031-A-2) SOX9 knockout human iPSC lines

Stem cell research, 2024-09, Vol.79, p.103484, Article 103484

2024

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Generation of a human ACTA1-tdTomato reporter iPSC line using CRISPR/Cas9 editing

Stem cell research, 2024-03, Vol.75, p.103313-103313, Article 103313

2024

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Generation of iPSC lines from peripheral blood mononuclear cells from five healthy donors

Stem cell research, 2023-06, Vol.69, p.103109-103109, Article 103109

2023

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Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

Stem cell research, 2024-04, Vol.76, p.103374-103374, Article 103374

2024

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In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia

Stem cells translational medicine, 2021-08, Vol.10 (8), p.1157-1169

2021

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Generating an iPSC line (with isogenic control) from the PBMCs of an ACTA1 (p.Gly148Asp) nemaline myopathy patient

Stem cell research, 2021-07, Vol.54, p.102429-102429, Article 102429

2021

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Simultaneous reprogramming and gene editing of human fibroblasts

Nature protocols, 2018-05, Vol.13 (5), p.875-898

2018

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Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis

Cellular extrusion bioprinting improves kidney organoid reproducibility and conformation

Introducing a Spectrum of Long-Range Genomic Deletions in Human Embryonic Stem Cells Using Type I CRISPR-Cas

Reproducibility and staging of 3D human retinal organoids across multiple pluripotent stem cell lines

Evaluation of variability in human kidney organoids

Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms

Plasticity of distal nephron epithelia from human kidney organoids enables the induction of ureteric tip and stalk

Renal Subcapsular Transplantation of PSC-Derived Kidney Organoids Induces Neo-vasculogenesis and Significant Glomerular and Tubular Maturation In Vivo

Enhanced metanephric specification to functional proximal tubule enables toxicity screening and infectious disease modelling in kidney organoids

Optic Vesicle‐like Structures Derived from Human Pluripotent Stem Cells Facilitate a Customized Approach to Retinal Disease Treatment

A Cas9 Variant for Efficient Generation of Indel-Free Knockin or Gene-Corrected Human Pluripotent Stem Cells

Kidney Organoids Generated Using an Allelic Series of NPHS2 Point Variants Reveal Distinct Intracellular Podocin Mistrafficking

Simultaneous Reprogramming and Gene Correction of Patient Fibroblasts

DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets

Genetic correction and analysis of induced pluripotent stem cells from a patient with gyrate atrophy

Phosphorylation regulates human OCT4

Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9

Direct reprogramming to human nephron progenitor-like cells using inducible piggyBac transposon expression of SNAI2-EYA1-SIX1

Generation of heterozygous (MCRIi031-A-1) and homozygous (MCRIi031-A-2) SOX9 knockout human iPSC lines

Generation of a human ACTA1-tdTomato reporter iPSC line using CRISPR/Cas9 editing

Generation of iPSC lines from peripheral blood mononuclear cells from five healthy donors

Generation of heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) NR2F2/COUP-TFII knockout human iPSC lines

In vivo survival and differentiation of Friedreich ataxia iPSC‐derived sensory neurons transplanted in the adult dorsal root ganglia

Generating an iPSC line (with isogenic control) from the PBMCs of an ACTA1 (p.Gly148Asp) nemaline myopathy patient

Simultaneous reprogramming and gene editing of human fibroblasts

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