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A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias

The Journal of pharmacology and experimental therapeutics, 2013-01, Vol.344 (1), p.23-32

2013

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Block of Na+ Currents and Suppression of Action Potentials in Cultured Hippocampal Neurons by Gs-458967

Biophysical journal, 2014-01, Vol.106 (2), p.326a-326a

2014

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Contribution of the late sodium current to intracellular sodium and calcium overload in rabbit ventricular myocytes treated by anemone toxin

American journal of physiology. Heart and circulatory physiology, 2016-02, Vol.310 (3), p.H426-H435

2016

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Eleclazine exhibits enhanced selectivity for long QT syndrome type 3–associated late Na+ current

Heart rhythm, 2018-02, Vol.15 (2), p.277-286

2018

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Inhibition of late Na+ current, a novel target to improve diastolic function and electrical abnormalities in Dahl salt-sensitive rats

American journal of physiology. Heart and circulatory physiology, 2016-05, Vol.310 (10), p.H1313-H1320

2016

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Ranolazine reduces neuronal excitability by interacting with inactivated states of brain sodium channels

Molecular pharmacology, 2014-01, Vol.85 (1), p.162-174

2014

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Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late I Nai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties

Journal of medicinal chemistry, 2016-10, Vol.59 (19), p.9005-9017

2016

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Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine

Neuropharmacology, 2012-06, Vol.62 (7), p.2250-2259

2012

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Characterization of RO5126946, a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator

The Journal of pharmacology and experimental therapeutics, 2014-08, Vol.350 (2), p.455

2014

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Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine

Bioorganic & medicinal chemistry letters, 2016-07, Vol.26 (13), p.3207-3211

2016

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Neuropharmacological properties of neurons derived from human stem cells

Neurochemistry international, 2011-09, Vol.59 (3), p.404-412

2011

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Characterization of RO5126946, a Novel α 7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator

The Journal of pharmacology and experimental therapeutics, 2014-08, Vol.350 (2), p.455-468

2014

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Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late I Na i) of the cardiac Na v 1.5 channel with improved efficacy and potency relative to ranolazine

Bioorganic & medicinal chemistry letters, 2016-07, Vol.26 (13), p.3207-3211

2016

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Ranolazine Reduces Central Neuron Excitability by Slowly Interacting with NaV Channels

Biophysical journal, 2012-01, Vol.102 (3), p.323a-323a

2012

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Enhancement of Slow Inactivation of Voltage-Gated Na + Channels by Ranolazine

Biophysical journal, 2011-02, Vol.100 (3), p.421a-421a

2011

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Neuropharmacological properties of neurons derived from human stem cells: The Potential of Stems Cells for 21st Century Neuroscience

Neurochemistry international, 2011, Vol.59 (3), p.404-412

2011

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An interaction between benzodiazepines and neuroactive steroids at GABAa receptors in cultured hippocampal neurons

Neurochemistry international, 2006-06, Vol.48 (8), p.703-707

2006

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Na^sub v^1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N^sub 1325^S mice

American Journal of Physiology: Cell Physiology, 2011-09, Vol.301 (3), p.C577

2011

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Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

American Journal of Physiology: Cell Physiology, 2011-09, Vol.301 (3), p.C577-586

2011

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Na v 1.5-dependent persistent Na + influx activates CaMKII in rat ventricular myocytes and N 1325 S mice

American Journal of Physiology: Cell Physiology, 2011-09, Vol.301 (3), p.C577-C586

2011

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Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

American Journal of Physiology: Cell Physiology, 2011, Vol.70 (3)

2011

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An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons

Neurochemistry international, 2006-06, Vol.48 (8), p.703-707

2006

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Effect of ciprofloxacin and biphenylacetic acid on voltage-gated ion channels in cultured rat hippocampal neurons

Neuroscience research, 2007, Vol.58, p.S189-S189

2007

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Electrophysiological studies of the interaction between ciprofloxacin and biphenylacetic acid at neuronal receptors and ion channels

Hirakawa, Ryoko

2009

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An interaction between benzodiazepines and neuroactive steroids at GABA sub(A) receptors in cultured hippocampal neurons

Neurochemistry international, 2006-01, Vol.48 (8), p.703-707

2006

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A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias

Block of Na+ Currents and Suppression of Action Potentials in Cultured Hippocampal Neurons by Gs-458967

Contribution of the late sodium current to intracellular sodium and calcium overload in rabbit ventricular myocytes treated by anemone toxin

Eleclazine exhibits enhanced selectivity for long QT syndrome type 3–associated late Na+ current

Inhibition of late Na+ current, a novel target to improve diastolic function and electrical abnormalities in Dahl salt-sensitive rats

Ranolazine reduces neuronal excitability by interacting with inactivated states of brain sodium channels

Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late I Nai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties

Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine

Characterization of RO5126946, a Novel α7 nicotinic acetylcholine receptor-positive allosteric modulator

Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late INai) of the cardiac Nav1.5 channel with improved efficacy and potency relative to ranolazine

Neuropharmacological properties of neurons derived from human stem cells

Characterization of RO5126946, a Novel α 7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator

Discovery of triazolopyridinone GS-462808, a late sodium current inhibitor (Late I Na i) of the cardiac Na v 1.5 channel with improved efficacy and potency relative to ranolazine

Ranolazine Reduces Central Neuron Excitability by Slowly Interacting with NaV Channels

Enhancement of Slow Inactivation of Voltage-Gated Na + Channels by Ranolazine

Neuropharmacological properties of neurons derived from human stem cells: The Potential of Stems Cells for 21st Century Neuroscience

An interaction between benzodiazepines and neuroactive steroids at GABAa receptors in cultured hippocampal neurons

Na^sub v^1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N^sub 1325^S mice

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

Na v 1.5-dependent persistent Na + influx activates CaMKII in rat ventricular myocytes and N 1325 S mice

Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice

An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons

Effect of ciprofloxacin and biphenylacetic acid on voltage-gated ion channels in cultured rat hippocampal neurons

Electrophysiological studies of the interaction between ciprofloxacin and biphenylacetic acid at neuronal receptors and ion channels

An interaction between benzodiazepines and neuroactive steroids at GABA sub(A) receptors in cultured hippocampal neurons

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