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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients

Nature communications, 2022-05, Vol.13 (1), p.2800-2800, Article 2800

2022

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CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

Nature communications, 2021-05, Vol.12 (1), p.3042-3042, Article 3042

2021

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Using Synthetically Engineered Guide RNAs to Enhance CRISPR Genome Editing Systems in Mammalian Cells

Frontiers in genome editing, 2021-01, Vol.2, p.617910

2021

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Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Molecular therapy. Nucleic acids, 2018-09, Vol.12, p.530-542

2018

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Homology-Directed-Repair-Based Genome Editing in HSPCs for the Treatment of Inborn Errors of Immunity and Blood Disorders

Pharmaceutics, 2023-04, Vol.15 (5), p.1329

2023

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Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34+ Hematopoietic Stem and Progenitor Cells

Molecular therapy, 2018-10, Vol.26 (10), p.2431-2442

2018

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A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell–Based Models for Cardiovascular Diseases

Circulation research, 2017-05, Vol.120 (10), p.1561-1571

2017

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CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications

Nature communications, 2023-10, Vol.14 (1), p.6771-16, Article 6771

2023

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Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing

Cell reports (Cambridge), 2014-04, Vol.7 (1), p.293-305

2014

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Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs

Molecular therapy. Nucleic acids, 2023-03, Vol.31, p.105-121

2023

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Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects

The Journal of experimental medicine, 2021-03, Vol.218 (3)

2021

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Nicotinamide-Expanded Allogeneic Natural Killer Cells with CD38 Deletion, Expressing an Enhanced CD38 Chimeric Antigen Receptor, Target Multiple Myeloma Cells

International journal of molecular sciences, 2023-12, Vol.24 (24), p.17231

2023

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Editorial: CRISPR and beyond: Cutting-edge technologies for gene correction in therapeutic applications

Frontiers in genome editing, 2023-04, Vol.5, p.1203864-1203864

2023

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Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System

Molecular therapy. Methods & clinical development, 2020-06, Vol.17, p.1097-1107

2020

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PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells

PLoS genetics, 2011-09, Vol.7 (9), p.e1002262

2011

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Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation

Frontiers in immunology, 2019-07, Vol.10, p.1672-1672

2019

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Separate Domains of Rev1 Mediate Two Modes of DNA Damage Bypass in Mammalian Cells

Molecular and Cellular Biology, 2009-06, Vol.29 (11), p.3113-3123

2009

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Evolution of Gene Therapy for Inborn Errors of Immunity

JAMA pediatrics, 2024-07, Vol.178 (7), p.645

2024

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Single-stranded DNA-binding Protein Recruits DNA Polymerase V to Primer Termini on RecA-coated DNA

The Journal of biological chemistry, 2008-03, Vol.283 (13), p.8274-8282

2008

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Quantifying on- and off-target genome editing

Trends in biotechnology (Regular ed.), 2015-02, Vol.33 (2), p.132-140

2015

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CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells

Nature (London), 2016-11, Vol.539 (7629), p.384-389

2016

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Quantifying allele-specific CRISPR editing activity with CRISPECTOR2.0

Nucleic acids research, 2024-09, Vol.52 (16), p.e78-e78

2024

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Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

Nature biotechnology, 2015-09, Vol.33 (9), p.985-989

2015

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The cell line A-to-I RNA editing catalogue

Nucleic acids research, 2020-06, Vol.48 (11), p.5849-5858

2020

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Chemical Modification of Guide RNAs for Improved CRISPR Activity in CD34+ Human Hematopoietic Stem and Progenitor Cells

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2162, p.37

2021

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Different hotspot p53 mutants exert distinct phenotypes and predict outcome of colorectal cancer patients

CRISPECTOR provides accurate estimation of genome editing translocation and off-target activity from comparative NGS data

Using Synthetically Engineered Guide RNAs to Enhance CRISPR Genome Editing Systems in Mammalian Cells

Uridine Depletion and Chemical Modification Increase Cas9 mRNA Activity and Reduce Immunogenicity without HPLC Purification

Homology-Directed-Repair-Based Genome Editing in HSPCs for the Treatment of Inborn Errors of Immunity and Blood Disorders

Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34+ Hematopoietic Stem and Progenitor Cells

A Comprehensive TALEN-Based Knockout Library for Generating Human-Induced Pluripotent Stem Cell–Based Models for Cardiovascular Diseases

CRISPR-Cas9 engineering of the RAG2 locus via complete coding sequence replacement for therapeutic applications

Quantifying genome-editing outcomes at endogenous loci with SMRT sequencing

Multiplex HDR for disease and correction modeling of SCID by CRISPR genome editing in human HSPCs

Inherited SLP76 deficiency in humans causes severe combined immunodeficiency, neutrophil and platelet defects

Nicotinamide-Expanded Allogeneic Natural Killer Cells with CD38 Deletion, Expressing an Enhanced CD38 Chimeric Antigen Receptor, Target Multiple Myeloma Cells

Editorial: CRISPR and beyond: Cutting-edge technologies for gene correction in therapeutic applications

Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells

Reduced Function and Diversity of T Cell Repertoire and Distinct Clinical Course in Patients With IL7RA Mutation

Separate Domains of Rev1 Mediate Two Modes of DNA Damage Bypass in Mammalian Cells

Evolution of Gene Therapy for Inborn Errors of Immunity

Single-stranded DNA-binding Protein Recruits DNA Polymerase V to Primer Termini on RecA-coated DNA

Quantifying on- and off-target genome editing

CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells

Quantifying allele-specific CRISPR editing activity with CRISPECTOR2.0

Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells

The cell line A-to-I RNA editing catalogue

Chemical Modification of Guide RNAs for Improved CRISPR Activity in CD34+ Human Hematopoietic Stem and Progenitor Cells

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