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Single-cell genomic approaches for developing the next generation of immunotherapies

Nature medicine, 2020-02, Vol.26 (2), p.171-177

2020

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The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

Cell, 2020-06, Vol.181 (6), p.1207-1217

2020

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Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

Cell, 2018-01, Vol.172 (1-2), p.14-21

2018

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Microglial immune checkpoint mechanisms

Nature neuroscience, 2018-06, Vol.21 (6), p.779-786

2018

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Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

Cell, 2018-05, Vol.173 (5), p.1073-1081

2018

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Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Nature medicine, 2020-06, Vol.26 (6), p.842-844

2020

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Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Science (American Association for the Advancement of Science), 2014-02, Vol.343 (6172), p.776-779

2014

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Dissecting cellular crosstalk by sequencing physically interacting cells

Nature biotechnology, 2020-05, Vol.38 (5), p.629-637

2020

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Impaired immune surveillance accelerates accumulation of senescent cells and aging

Nature communications, 2018-12, Vol.9 (1), p.5435-15, Article 5435

2018

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Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

Nature cell biology, 2018-07, Vol.20 (7), p.836-846

2018

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Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Science (American Association for the Advancement of Science), 2017-12, Vol.358 (6370), p.1622-1627

2017

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Plasmacytoid dendritic cells develop from Ly6D + lymphoid progenitors distinct from the myeloid lineage

Nature immunology, 2019-07, Vol.20 (7), p.852-864

2019

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Cell composition analysis of bulk genomics using single-cell data

Nature methods, 2019-04, Vol.16 (4), p.327-332

2019

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Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

Cell, 2020-06, Vol.181 (7), p.1475-1488.e12

2020

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PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

Nature communications, 2019-01, Vol.10 (1), p.465-465, Article 465

2019

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Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Nature communications, 2021-05, Vol.12 (1), p.3074-3074, Article 3074

2021

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Full-length transcriptome assembly from RNA-Seq data without a reference genome

Nature biotechnology, 2011-07, Vol.29 (7), p.644-652

2011

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MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

Nature protocols, 2019-06, Vol.14 (6), p.1841-1862

2019

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Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells

Immunity (Cambridge, Mass.), 2017-05, Vol.46 (5), p.849-862.e7

2017

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From the Human Cell Atlas to dynamic immune maps in human disease

Nature reviews. Immunology, 2018-10, Vol.18 (10), p.597-598

2018

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Deciphering the state of immune silence in fatal COVID-19 patients

Nature communications, 2021-03, Vol.12 (1), p.1428-1428, Article 1428

2021

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Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Cell, 2019-07, Vol.178 (3), p.686-698.e14

2019

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Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress

Molecular psychiatry, 2020-05, Vol.25 (5), p.1050-1067

2020

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Microglia development follows a stepwise program to regulate brain homeostasis

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6301), p.789-789

2016

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Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

Immunity (Cambridge, Mass.), 2018-05, Vol.48 (5), p.951-962.e5

2018

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Single-cell genomic approaches for developing the next generation of immunotherapies

The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

Single-Cell Genomics: A Stepping Stone for Future Immunology Discoveries

Microglial immune checkpoint mechanisms

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Dissecting cellular crosstalk by sequencing physically interacting cells

Impaired immune surveillance accelerates accumulation of senescent cells and aging

Single-cell characterization of haematopoietic progenitors and their trajectories in homeostasis and perturbed haematopoiesis

Spatial reconstruction of immune niches by combining photoactivatable reporters and scRNA-seq

Plasmacytoid dendritic cells develop from Ly6D + lymphoid progenitors distinct from the myeloid lineage

Cell composition analysis of bulk genomics using single-cell data

Host-Viral Infection Maps Reveal Signatures of Severe COVID-19 Patients

PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model

Clump sequencing exposes the spatial expression programs of intestinal secretory cells

Full-length transcriptome assembly from RNA-Seq data without a reference genome

MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing

Genomic Characterization of Murine Monocytes Reveals C/EBPβ Transcription Factor Dependence of Ly6C− Cells

From the Human Cell Atlas to dynamic immune maps in human disease

Deciphering the state of immune silence in fatal COVID-19 patients

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner

Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress

Microglia development follows a stepwise program to regulate brain homeostasis

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies

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