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C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation

Nature communications, 2018-01, Vol.9 (1), p.51-12, Article 51

2018

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C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import

eLife, 2020-03, Vol.9

2020

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

Neuron (Cambridge, Mass.), 2019-12, Vol.104 (5), p.885-898.e8

2019

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A Helicase Unwinds Hexanucleotide Repeat RNA G‑Quadruplexes and Facilitates Repeat-Associated Non-AUG Translation

Journal of the American Chemical Society, 2021-05, Vol.143 (19), p.7368-7379

2021

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Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

Nature communications, 2021-08, Vol.12 (1), p.1-14, Article 4908

2021

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C9ORF72-ALS/FTD: Transgenic Mice Make a Come-BAC

Neuron (Cambridge, Mass.), 2016-05, Vol.90 (3), p.427-431

2016

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RNA-mediated ribonucleoprotein assembly controls TDP-43 nuclear retention

PLoS biology, 2024-02, Vol.22 (2), p.e3002527-e3002527

2024

Volltextzugriff (PDF)

Order from chaos: Using CSF proteomics to predict ALS progression

Annals of clinical and translational neurology, 2023-12, Vol.10 (12), p.2176-2178

2023

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UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction

Cell reports (Cambridge), 2021-03, Vol.34 (13), p.108925-108925, Article 108925

2021

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Elevated nuclear TDP-43 induces constitutive exon skipping

Molecular neurodegeneration, 2024-06, Vol.19 (1), p.45-17

2024

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Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Neurotherapeutics, 2022-07, Vol.19 (4), p.1061-1084

2022

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Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

iScience, 2024-06, Vol.27 (6), p.110109, Article 110109

2024

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DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD

Experimental neurology, 2024-06, Vol.376, p.114768-114768, Article 114768

2024

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Dancing muscles: the value of real-time ultrasound evaluation of muscle in myositis and mimics

Rheumatology (Oxford, England), 2021-08, Vol.60 (8), p.e275-e276

2021

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Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72 -associated amyotrophic lateral sclerosis

Science translational medicine, 2017-03, Vol.9 (383)

2017

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Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal

Experimental neurology, 2019-08, Vol.318, p.251-257

2019

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Axonal degeneration in the peripheral nervous system: Implications for the pathogenesis of amyotrophic lateral sclerosis

Experimental neurology, 2013-08, Vol.246, p.6-13

2013

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Hexanucleotide repeat induced nuclear export and translation of circular intronic RNA in C9ORF72-ALS/FTD

Biophysical journal, 2022-02, Vol.121 (3), p.311a-311a

2022

Volltextzugriff (PDF)

Axonal degeneration in the peripheral nervous system: Implications for the pathogenesis of amyotrophic lateral sclerosis: Axonal degeneration

Experimental neurology, 2013, Vol.246, p.6-13

2013

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Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats

Nature communications, 2023-03, Vol.14 (1), p.1755-1755, Article 1755

2023

Volltextzugriff (PDF)

Early-life influences of low-calorie sweetener consumption on sugar taste

Physiology & behavior, 2023-05, Vol.264, p.114133-114133, Article 114133

2023

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Hypothalamic REV-ERB nuclear receptors control diurnal food intake and leptin sensitivity in diet-induced obese mice

The Journal of clinical investigation, 2021-01, Vol.131 (1), p.1-12

2021

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Hypothalamus-hippocampus circuitry regulates impulsivity via melanin-concentrating hormone

Nature communications, 2019-10, Vol.10 (1), p.4923-16, Article 4923

2019

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Early Life Low-Calorie Sweetener Consumption Impacts Energy Balance during Adulthood

Nutrients, 2022-11, Vol.14 (22), p.4709

2022

Volltextzugriff (PDF)

RTEL1 and MCM10 overcome topological stress during vertebrate replication termination

Cell reports (Cambridge), 2023-02, Vol.42 (2), p.112109-112109, Article 112109

2023

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C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation

C9orf72 arginine-rich dipeptide repeat proteins disrupt karyopherin-mediated nuclear import

CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

A Helicase Unwinds Hexanucleotide Repeat RNA G‑Quadruplexes and Facilitates Repeat-Associated Non-AUG Translation

Nuclear export and translation of circular repeat-containing intronic RNA in C9ORF72-ALS/FTD

C9ORF72-ALS/FTD: Transgenic Mice Make a Come-BAC

RNA-mediated ribonucleoprotein assembly controls TDP-43 nuclear retention

Order from chaos: Using CSF proteomics to predict ALS progression

UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction

Elevated nuclear TDP-43 induces constitutive exon skipping

Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD

Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes

DDX3X overexpression decreases dipeptide repeat proteins in a mouse model of C9ORF72-ALS/FTD

Dancing muscles: the value of real-time ultrasound evaluation of muscle in myositis and mimics

Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72 -associated amyotrophic lateral sclerosis

Distal denervation in the SOD1 knockout mouse correlates with loss of mitochondria at the motor nerve terminal

Axonal degeneration in the peripheral nervous system: Implications for the pathogenesis of amyotrophic lateral sclerosis

Hexanucleotide repeat induced nuclear export and translation of circular intronic RNA in C9ORF72-ALS/FTD

Axonal degeneration in the peripheral nervous system: Implications for the pathogenesis of amyotrophic lateral sclerosis: Axonal degeneration

Hypothalamic melanin-concentrating hormone neurons integrate food-motivated appetitive and consummatory processes in rats

Early-life influences of low-calorie sweetener consumption on sugar taste

Hypothalamic REV-ERB nuclear receptors control diurnal food intake and leptin sensitivity in diet-induced obese mice

Hypothalamus-hippocampus circuitry regulates impulsivity via melanin-concentrating hormone

Early Life Low-Calorie Sweetener Consumption Impacts Energy Balance during Adulthood

RTEL1 and MCM10 overcome topological stress during vertebrate replication termination

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