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Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease

Neuron (Cambridge, Mass.), 2014-10, Vol.84 (1), p.63-77

2014

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Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

The Journal of biological chemistry, 2015-10, Vol.290 (43), p.26043-26050

2015

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Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

The Journal of experimental medicine, 2018-09, Vol.215 (9), p.2235-2245

2018

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Soluble TREM2 induces inflammatory responses and enhances microglial survival

The Journal of experimental medicine, 2017-03, Vol.214 (3), p.597-607

2017

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Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Genome Biology, 2019-05, Vol.20 (1), p.97-97, Article 97

2019

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Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J mice

Journal of applied physiology (1985), 2015-04, Vol.118 (8), p.1059-1066

2015

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Large-scale topology and the default mode network in the mouse connectome

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (52), p.18745-18750

2014

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Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (35), p.E2334-E2342

2012

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Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer's disease neuropathology

Molecular neurodegeneration, 2021-01, Vol.16 (1), p.5-5, Article 5

2021

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Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Molecular neurodegeneration, 2019-02, Vol.14 (1), p.9-15, Article 9

2019

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Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways

Proceedings of the National Academy of Sciences - PNAS, 2017-08, Vol.114 (33), p.E6962-E6971

2017

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Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis

PLoS genetics, 2010-07, Vol.6 (7), p.e1001021-e1001021

2010

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TREM2 in CNS homeostasis and neurodegenerative disease

Molecular neurodegeneration, 2015-09, Vol.10 (1), p.43-43, Article 43

2015

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Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro

Molecular neurodegeneration, 2022-03, Vol.17 (1), p.26-26, Article 26

2022

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Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease

Acta neuropathologica, 2016-08, Vol.132 (2), p.225-234

2016

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Exercise and Genetic Rescue of SCA1 via the Transcriptional Repressor Capicua

Science (American Association for the Advancement of Science), 2011-11, Vol.334 (6056), p.690-693

2011

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APOE2 is associated with longevity independent of Alzheimer's disease

eLife, 2020-10, Vol.9

2020

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ATXN1 Protein Family and CIC Regulate Extracellular Matrix Remodeling and Lung Alveolarization

Developmental cell, 2011-10, Vol.21 (4), p.746-757

2011

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Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: implications for clinical use and genetic discovery efforts in human disease

Molecular neurodegeneration, 2018-08, Vol.13 (1), p.46-17, Article 46

2018

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Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

Cell reports (Cambridge), 2020-05, Vol.31 (5), p.107616-107616, Article 107616

2020

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A matter of balance

eLife, 2018-08, Vol.7

2018

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ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE

The Journal of biological chemistry, 2004-09, Vol.279 (39), p.40987-40993

2004

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Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

Nature communications, 2017-07, Vol.8 (1), p.16037-16037, Article 16037

2017

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Commonly disrupted pathways in brain and kidney in a pig model of systemic endotoxemia

Journal of neuroinflammation, 2024-01, Vol.21 (1), p.9-9, Article 9

2024

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Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease

Apolipoprotein E Is a Ligand for Triggering Receptor Expressed on Myeloid Cells 2 (TREM2)

Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

Poly(GR) impairs protein translation and stress granule dynamics in C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis

Soluble TREM2 induces inflammatory responses and enhances microglial survival

Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight

Voluntary and forced exercise differentially alters the gut microbiome in C57BL/6J mice

Large-scale topology and the default mode network in the mouse connectome

Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder

Clusterin secreted from astrocyte promotes excitatory synaptic transmission and ameliorates Alzheimer's disease neuropathology

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways

Partial loss of ataxin-1 function contributes to transcriptional dysregulation in spinocerebellar ataxia type 1 pathogenesis

TREM2 in CNS homeostasis and neurodegenerative disease

Culture shock: microglial heterogeneity, activation, and disrupted single-cell microglial networks in vitro

Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease

Exercise and Genetic Rescue of SCA1 via the Transcriptional Repressor Capicua

APOE2 is associated with longevity independent of Alzheimer's disease

ATXN1 Protein Family and CIC Regulate Extracellular Matrix Remodeling and Lung Alveolarization

Long-read sequencing across the C9orf72 'GGGGCC' repeat expansion: implications for clinical use and genetic discovery efforts in human disease

Hexanucleotide Repeat Expansions in c9FTD/ALS and SCA36 Confer Selective Patterns of Neurodegeneration In Vivo

A matter of balance

ABCA1 Is Required for Normal Central Nervous System ApoE Levels and for Lipidation of Astrocyte-secreted apoE

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5

Commonly disrupted pathways in brain and kidney in a pig model of systemic endotoxemia

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