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1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Bioorganic & medicinal chemistry letters, 2001-07, Vol.11 (14), p.1907-1910

2001

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Comparison of azabicyclic esters and oxadiazoles as ligands for the muscarinic receptor

Journal of medicinal chemistry, 1991-09, Vol.34 (9), p.2726-2735

1991

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Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist

Journal of medicinal chemistry, 2003-11, Vol.46 (23), p.4952-4964

2003

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3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.737-741

2005

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Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Journal of medicinal chemistry, 2000-05, Vol.43 (9), p.1878-1885

2000

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The design of 8,8-Dimethyl[1,6]naphthyridines as potential anticonvulsant agents

Bioorganic & medicinal chemistry letters, 2003-05, Vol.13 (10), p.1627-1629

2003

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8-piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines : Potent, selective, orally bioavailable 5-HT1 receptor ligands

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4370-4374

2005

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Taking a Stand Against Air Pollution-The Impact on Cardiovascular Disease: A Joint Opinion from the World Heart Federation, American College of Cardiology, American Heart Association, and the European Society of Cardiology

Journal of the American College of Cardiology, 2021-04, Vol.77 (13), p.1684-1688

2021

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Identification of a potent and selective 5-HT1B receptor antagonist

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (21), p.4708-4712

2005

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Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.285-290

1999

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Taking a stand against air pollution - the impact on cardiovascular disease

European heart journal, 2021-04, Vol.42 (15), p.1460-1463

2021

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Design and Synthesis of 2-Naphthoate Esters as Selective Dopamine D4 Antagonists

Journal of medicinal chemistry, 1996-05, Vol.39 (10), p.1946-1948

1996

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Design of [R-(Z)]-(+)-α-(Methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitrile (SB 202026), a Functionally Selective Azabicyclic Muscarinic M1 Agonist Incorporating the N-Methoxy Imidoyl Nitrile Group as a Novel Ester Bioisostere

Journal of medicinal chemistry, 1997-12, Vol.40 (26), p.4265-4280

1997

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Heterocyclic analogues of 2-aminotetralins with high affinity and selectivity for the dopamine D3 receptor

Bioorganic & medicinal chemistry letters, 1999-09, Vol.9 (18), p.2715-2720

1999

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Synthesis and antihypertensive activity of 3-[(substituted-carbonyl)amino]-2H-1-benzopyrans

Journal of medicinal chemistry, 1992-05, Vol.35 (9), p.1623-1627

1992

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Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D3 receptor

Bioorganic & medicinal chemistry letters, 2000-11, Vol.10 (22), p.2553-2555

2000

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Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4537-4539

1996

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Substituted benzamides with conformationally restricted side chains. 5. Azabicyclo[x.y.z] derivatives as 5-HT4 receptor agonists and gastric motility stimulants

Journal of medicinal chemistry, 1993-03, Vol.36 (6), p.683-689

1993

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Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols

Bioorganic & medicinal chemistry letters, 1997-06, Vol.7 (12), p.1573-1576

1997

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Synthesis of Functionalised Azabicycles via a Regiospecific Intramolecular Aldol Reaction

Synlett, 1996-09, Vol.1996 (9), p.853-855

1996

Volltextzugriff (PDF)

Stereochemical differentiation of anticonvulsant and antihypertensive effects in 4-(fluorobenzoylamino)-benzopyrans

Bioorganic & medicinal chemistry letters, 1995-06, Vol.5 (11), p.1163-1166

1995

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Substituted 3-amino-1,1-diaryl-2-propanols as potential antidepressant agents

Journal of medicinal chemistry, 1979-11, Vol.22 (11), p.1373-1379

1979

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Substituted benzamides with conformationally restricted side chains. 2. Indolizidine derivatives as central dopamine receptor antagonists

Journal of medicinal chemistry, 1988-09, Vol.31 (9), p.1708-1712

1988

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Substituted benzamides with conformationally restricted side chains. 1. Quinolizidine derivatives as selective gastric prokinetic agents

Journal of medicinal chemistry, 1985-12, Vol.28 (12), p.1843-1847

1985

Volltextzugriff (PDF)

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1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor

Comparison of azabicyclic esters and oxadiazoles as ligands for the muscarinic receptor

Design and Synthesis of trans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3 Receptor Antagonist

3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity

Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

The design of 8,8-Dimethyl[1,6]naphthyridines as potential anticonvulsant agents

8-piperazinyl-2,3-dihydropyrrolo[3,2-g]isoquinolines : Potent, selective, orally bioavailable 5-HT1 receptor ligands

Taking a Stand Against Air Pollution-The Impact on Cardiovascular Disease: A Joint Opinion from the World Heart Federation, American College of Cardiology, American Heart Association, and the European Society of Cardiology

Identification of a potent and selective 5-HT1B receptor antagonist

Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Taking a stand against air pollution - the impact on cardiovascular disease

Design and Synthesis of 2-Naphthoate Esters as Selective Dopamine D4 Antagonists

Design of [R-(Z)]-(+)-α-(Methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitrile (SB 202026), a Functionally Selective Azabicyclic Muscarinic M1 Agonist Incorporating the N-Methoxy Imidoyl Nitrile Group as a Novel Ester Bioisostere

Heterocyclic analogues of 2-aminotetralins with high affinity and selectivity for the dopamine D3 receptor

Synthesis and antihypertensive activity of 3-[(substituted-carbonyl)amino]-2H-1-benzopyrans

Novel 2,3,4,5-tetrahydro-1H-3-benzazepines with high affinity and selectivity for the dopamine D3 receptor

Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Substituted benzamides with conformationally restricted side chains. 5. Azabicyclo[x.y.z] derivatives as 5-HT4 receptor agonists and gastric motility stimulants

Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols

Synthesis of Functionalised Azabicycles via a Regiospecific Intramolecular Aldol Reaction

Stereochemical differentiation of anticonvulsant and antihypertensive effects in 4-(fluorobenzoylamino)-benzopyrans

Design and Synthesis of trans - N -[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D 3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat

Substituted 3-amino-1,1-diaryl-2-propanols as potential antidepressant agents

Substituted benzamides with conformationally restricted side chains. 2. Indolizidine derivatives as central dopamine receptor antagonists

Substituted benzamides with conformationally restricted side chains. 1. Quinolizidine derivatives as selective gastric prokinetic agents

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