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One size does not fit all: Lysosomes exist in biochemically and functionally distinct states

PLoS biology, 2024-03, Vol.22 (3), p.e3002576-e3002576

2024

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The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

Immunity (Cambridge, Mass.), 2019-07, Vol.51 (1), p.77-89.e6

2019

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Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

Nature immunology, 2014-11, Vol.15 (11), p.1017-1025

2014

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LRRK2 activation controls the repair of damaged endomembranes in macrophages

The EMBO journal, 2020-09, Vol.39 (18), p.e104494-n/a

2020

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Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

Nature communications, 2021-06, Vol.12 (1), p.3816-3816, Article 3816

2021

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Biocompatible Magnetic Micro‐ and Nanodevices: Fabrication of FePt Nanopropellers and Cell Transfection

Advanced materials (Weinheim), 2020-06, Vol.32 (25), p.e2001114-n/a

2020

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Rab GTPases in Immunity and Inflammation

Frontiers in cellular and infection microbiology, 2017-09, Vol.7, p.435-435

2017

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Mycobacterium tuberculosis infection of host cells in space and time

FEMS microbiology reviews, 2019-07, Vol.43 (4), p.341-361

2019

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Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

mBio, 2024-08, Vol.15 (8), p.e0035324

2024

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Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

Nature communications, 2022-11, Vol.13 (1), p.7338-22, Article 7338

2022

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The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection

eLife, 2020-05, Vol.9

2020

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Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells

BMC biology, 2018-01, Vol.16 (1), p.1-13, Article 1

2018

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A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity

Cell host & microbe, 2017-05, Vol.21 (5), p.619-628.e5

2017

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Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs

PLoS biology, 2020-12, Vol.18 (12), p.e3000879

2020

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Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

Cell, 2004-12, Vol.119 (6), p.753-766

2004

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3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy

Journal of cell science, 2017-01, Vol.130 (1), p.278-291

2017

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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages

The Journal of clinical investigation, 2023-03, Vol.133 (6), p.1-17

2023

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Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis

mBio, 2022-04, Vol.13 (2), p.e0011722

2022

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Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

PLoS pathogens, 2021-03, Vol.17 (3), p.e1009410

2021

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Progress in robotics for combating infectious diseases

Science robotics, 2021-03, Vol.6 (52)

2021

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miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

PLoS biology, 2019-03, Vol.17 (3), p.e2006716-e2006716

2019

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Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes

Nature communications, 2019-09, Vol.10 (1), p.4177-11, Article 4177

2019

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ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages

Nature microbiology, 2023-05, Vol.8 (5), p.803-818

2023

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Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

Journal of cell science, 2004-06, Vol.117 (Pt 13), p.2687-2697

2004

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High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages

FEBS open bio, 2023-07, Vol.13 (7), p.1204-1217

2023

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One size does not fit all: Lysosomes exist in biochemically and functionally distinct states

The Intestine Harbors Functionally Distinct Homeostatic Tissue-Resident and Inflammatory Th17 Cells

Neutrophils sense microbe size and selectively release neutrophil extracellular traps in response to large pathogens

LRRK2 activation controls the repair of damaged endomembranes in macrophages

Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

Biocompatible Magnetic Micro‐ and Nanodevices: Fabrication of FePt Nanopropellers and Cell Transfection

Rab GTPases in Immunity and Inflammation

Mycobacterium tuberculosis infection of host cells in space and time

Physiologic medium renders human iPSC-derived macrophages permissive for M. tuberculosis by rewiring organelle function and metabolism

Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism

The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection

Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells

A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity

Correlative light electron ion microscopy reveals in vivo localisation of bedaquiline in Mycobacterium tuberculosis-infected lungs

Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

3D correlative light and electron microscopy of cultured cells using serial blockface scanning electron microscopy

A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages

Visualizing Pyrazinamide Action by Live Single-Cell Imaging of Phagosome Acidification and Mycobacterium tuberculosis pH Homeostasis

Macrophage-specific responses to human- and animal-adapted tubercle bacilli reveal pathogen and host factors driving multinucleated cell formation

Progress in robotics for combating infectious diseases

miR-181a/b-1 controls thymic selection of Treg cells and tunes their suppressive capacity

Comparative fitness analysis of D-cycloserine resistant mutants reveals both fitness-neutral and high-fitness cost genotypes

ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages

Rab7 is required for the normal progression of the autophagic pathway in mammalian cells

High content quantitative imaging of Mycobacterium tuberculosis responses to acidic microenvironments within human macrophages

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