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G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers

FEBS letters, 2020-12, Vol.594 (24), p.4201-4232

2020

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Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER + breast cancer

Nature communications, 2022-02, Vol.13 (1), p.1061-1061, Article 1061

2022

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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

Cancer cell, 2014-06, Vol.25 (6), p.831-845

2014

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B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade

Clinical cancer research, 2020-07, Vol.26 (13), p.3345-3359

2020

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G-protein-coupled receptors and cancer

Nature reviews. Cancer, 2007-02, Vol.7 (2), p.79-94

2007

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Transcriptional signature primes human oral mucosa for rapid wound healing

Science translational medicine, 2018-07, Vol.10 (451)

2018

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mTOR co-targeting strategies for head and neck cancer therapy

Cancer and metastasis reviews, 2017-09, Vol.36 (3), p.491-502

2017

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The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma

Clinical cancer research, 2018-02, Vol.24 (3), p.619-633

2018

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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics

Clinical cancer research, 2019-07, Vol.25 (14), p.4211-4223

2019

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Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas

Molecular cancer therapeutics, 2020-09, Vol.19 (9), p.1784-1796

2020

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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

Nature communications, 2019-12, Vol.10 (1), p.5546-13, Article 5546

2019

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The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer

Nature reviews. Cancer, 2013-06, Vol.13 (6), p.412

2013

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mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

Cell stem cell, 2012-09, Vol.11 (3), p.401-414

2012

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Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

Analyst (London), 2010-01, Vol.135 (1), p.2496-2511

2010

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Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy

The Journal of biological chemistry, 2019-07, Vol.294 (29), p.11062-11086

2019

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Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Nature communications, 2018-07, Vol.9 (1), p.2372-13, Article 2372

2018

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Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum

Biosensors & bioelectronics, 2011-07, Vol.26 (11), p.4477-4483

2011

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mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

Cell stem cell, 2009-09, Vol.5 (3), p.279-289

2009

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Angiopoietin-1 Prevents VEGF-Induced Endothelial Permeability by Sequestering Src through mDia

Developmental cell, 2008-01, Vol.14 (1), p.25-36

2008

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HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers

Oncogene, 2020-10, Vol.39 (40), p.6327-6339

2020

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Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets

Cancer discovery, 2013-07, Vol.3 (7), p.722-725

2013

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Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Nature communications, 2021-04, Vol.12 (1), p.2383-2383, Article 2383

2021

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Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis

Oncogene, 2020-05, Vol.39 (20), p.4014-4027

2020

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Ultrasensitive Detection of Cancer Biomarkers in the Clinic by Use of a Nanostructured Microfluidic Array

Analytical chemistry (Washington), 2012-07, Vol.84 (14), p.6249-6255

2012

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4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (7), p.1438-1450

2019

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G Protein‐Coupled receptors and heterotrimeric G proteins as cancer drivers

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER + breast cancer

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade

G-protein-coupled receptors and cancer

Transcriptional signature primes human oral mucosa for rapid wound healing

mTOR co-targeting strategies for head and neck cancer therapy

The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma

Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics

Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum

mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

Angiopoietin-1 Prevents VEGF-Induced Endothelial Permeability by Sequestering Src through mDia

HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers

Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis

Ultrasensitive Detection of Cancer Biomarkers in the Clinic by Use of a Nanostructured Microfluidic Array

4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer

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