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G-protein-coupled receptors and cancer

Nature reviews. Cancer, 2007-02, Vol.7 (2), p.79-94

2007

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Arrestins as rheostats of GPCR signalling

Nature reviews. Molecular cell biology, 2018-10, Vol.19 (10), p.615

2018

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Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER + breast cancer

Nature communications, 2022-02, Vol.13 (1), p.1061-1061, Article 1061

2022

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Transcriptional signature primes human oral mucosa for rapid wound healing

Science translational medicine, 2018-07, Vol.10 (451)

2018

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Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy

The Journal of biological chemistry, 2019-07, Vol.294 (29), p.11062-11086

2019

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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

Cancer cell, 2014-06, Vol.25 (6), p.831-845

2014

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mTOR co-targeting strategies for head and neck cancer therapy

Cancer and metastasis reviews, 2017-09, Vol.36 (3), p.491-502

2017

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B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade

Clinical cancer research, 2020-07, Vol.26 (13), p.3345-3359

2020

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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

Nature communications, 2019-12, Vol.10 (1), p.5546-13, Article 5546

2019

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The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma

Clinical cancer research, 2018-02, Vol.24 (3), p.619-633

2018

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Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum

Biosensors & bioelectronics, 2011-07, Vol.26 (11), p.4477-4483

2011

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Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

Analyst (London), 2010-10, Vol.135 (1), p.2496-2511

2010

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Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

Nature communications, 2018-07, Vol.9 (1), p.2372-13, Article 2372

2018

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mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

Cell stem cell, 2012-09, Vol.11 (3), p.401-414

2012

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Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets

Cancer discovery, 2013-07, Vol.3 (7), p.722-725

2013

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Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging

Science (American Association for the Advancement of Science), 2007-08, Vol.317 (5839), p.803-806

2007

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Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics

Clinical cancer research, 2019-07, Vol.25 (14), p.4211-4223

2019

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Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas

Molecular cancer therapeutics, 2020-09, Vol.19 (9), p.1784-1796

2020

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Ultrasensitive Electrochemical Immunosensor for Oral Cancer Biomarker IL-6 Using Carbon Nanotube Forest Electrodes and Multilabel Amplification

Analytical chemistry (Washington), 2010-04, Vol.82 (8), p.3118-3123

2010

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Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer

Cell research, 2012-01, Vol.22 (1), p.23-32

2012

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PRECOG: PREdicting COupling probabilities of G-protein coupled receptors

Nucleic acids research, 2019-07, Vol.47 (W1), p.W395

2019

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Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Nature communications, 2021-04, Vol.12 (1), p.2383-2383, Article 2383

2021

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Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling

Scientific reports, 2015-06, Vol.5 (1), p.11541-11541, Article 11541

2015

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Molecular Mechanisms Deployed by Virally Encoded G Protein―Coupled Receptors in Human Diseases

Annual review of pharmacology and toxicology, 2013-01, Vol.53 (1), p.331-354

2013

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4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer

Cancer research (Chicago, Ill.), 2019-04, Vol.79 (7), p.1438-1450

2019

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G-protein-coupled receptors and cancer

Arrestins as rheostats of GPCR signalling

Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER + breast cancer

Transcriptional signature primes human oral mucosa for rapid wound healing

Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy

Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry

mTOR co-targeting strategies for head and neck cancer therapy

B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade

Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma

Microfluidic electrochemical immunoarray for ultrasensitive detection of two cancer biomarker proteins in serum

Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer

Assembly and activation of the Hippo signalome by FAT1 tumor suppressor

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

Exploiting the head and neck cancer oncogenome: widespread PI3K-mTOR pathway alterations and novel molecular targets

Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging

Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics

Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas

Ultrasensitive Electrochemical Immunosensor for Oral Cancer Biomarker IL-6 Using Carbon Nanotube Forest Electrodes and Multilabel Amplification

Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer

PRECOG: PREdicting COupling probabilities of G-protein coupled receptors

Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer

Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling

Molecular Mechanisms Deployed by Virally Encoded G Protein―Coupled Receptors in Human Diseases

4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer

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