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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens

Nature (London), 1994-09, Vol.371 (6492), p.72-74

1994

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Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling

Human molecular genetics, 2017-08, Vol.26 (15), p.2949-2960

2017

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Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

Development (Cambridge), 2014-06, Vol.141 (11), p.2206-2215

2014

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Low-Density Lipoprotein Receptor-Related Proteins in Skeletal Development and Disease

Physiological reviews, 2017-07, Vol.97 (3), p.1211-1228

2017

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An osteocalcin-deficient mouse strain without endocrine abnormalities

PLoS genetics, 2020-05, Vol.16 (5), p.e1008361-e1008361

2020

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Beta‐catenin signaling in murine liver zonation and regeneration: A Wnt‐Wnt situation

Hepatology (Baltimore, Md.), 2014-09, Vol.60 (3), p.964-976

2014

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Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone

Journal of bone and mineral research, 2009-02, Vol.24 (2), p.171-178

2009

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Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

Journal of bone and mineral research, 2016-01, Vol.31 (1), p.65-75

2016

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mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

Cell stem cell, 2009-09, Vol.5 (3), p.279-289

2009

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Lrp5 functions in bone to regulate bone mass

Nature medicine, 2011-06, Vol.17 (6), p.684-691

2011

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Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells

Nature (London), 2011-05, Vol.474 (7352), p.511-515

2011

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Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization

Genes & development, 2017-05, Vol.31 (9), p.916-926

2017

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TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Cell, 2006-09, Vol.126 (5), p.955-968

2006

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Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition

PloS one, 2013-05, Vol.8 (5), p.e63323-e63323

2013

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The Past, Present, and Future of Genetically Engineered Mouse Models for Skeletal Biology

Biomolecules (Basel, Switzerland), 2023-08, Vol.13 (9), p.1311

2023

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Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (20), p.9721-9730

2007

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Wntless functions in mature osteoblasts to regulate bone mass

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (33), p.E2197-E2204

2012

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Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma

PloS one, 2013-09, Vol.8 (9), p.e74191-e74191

2013

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Down regulation of Wnt signaling mitigates hypoxia-induced chemoresistance in human osteosarcoma cells

PloS one, 2014-10, Vol.9 (10), p.e111431

2014

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Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

PloS one, 2008-10, Vol.3 (10), p.e3581-e3581

2008

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Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway

Nature communications, 2018-01, Vol.9 (1), p.143-143, Article 143

2018

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LRP5: From bedside to bench to bone

Bone (New York, N.Y.), 2017-09, Vol.102, p.26-30

Williams, Bart O

2017

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A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice

Bone research, 2013-03, Vol.1 (1), p.27-71

2013

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The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development

PloS one, 2009-06, Vol.4 (6), p.e5813

2009

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Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy

Bone research, 2018-05, Vol.6, p.17-10

2018

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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens

Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling

Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts

Low-Density Lipoprotein Receptor-Related Proteins in Skeletal Development and Disease

An osteocalcin-deficient mouse strain without endocrine abnormalities

Beta‐catenin signaling in murine liver zonation and regeneration: A Wnt‐Wnt situation

Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone

Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

mTOR Mediates Wnt-Induced Epidermal Stem Cell Exhaustion and Aging

Lrp5 functions in bone to regulate bone mass

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells

Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization

TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Lrp5 and Lrp6 exert overlapping functions in osteoblasts during postnatal bone acquisition

The Past, Present, and Future of Genetically Engineered Mouse Models for Skeletal Biology

Mouse model of colonic adenoma-carcinoma progression based on somatic Apc inactivation

Wntless functions in mature osteoblasts to regulate bone mass

Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma

Down regulation of Wnt signaling mitigates hypoxia-induced chemoresistance in human osteosarcoma cells

Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia

Desumoylase SENP6 maintains osteochondroprogenitor homeostasis by suppressing the p53 pathway

LRP5: From bedside to bench to bone

A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice

The Wnt co-receptor Lrp6 is required for normal mouse mammary gland development

Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy

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