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Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5218), p.1721-1727

1995

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Structural characterization of the complex between TIGIT and the Fab of MK684, a novel antibody for immunotherapy

Acta crystallographica. Section A, Foundations and advances, 2023-08, Vol.79 (a2), p.C952-C952

Fischmann, T. O.

2023

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Small rearrangements in structures of Fv and Fab fragments of antibody D 1.3 on antigen binding

Nature (London), 1990-10, Vol.347 (6292), p.483-485

1990

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Peptidic inhibitors of the hepatitis C virus serine protease within non-structural protein 3

Current pharmaceutical design, 2002-01, Vol.8 (28), p.2533-2540

2002

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Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen binding

Nature (London), 1990-10, Vol.347 (6292), p.483-485

1990

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Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

Nature structural biology, 1999-03, Vol.6 (3), p.233-242

1999

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Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolution

The Journal of biological chemistry, 1991-07, Vol.266 (20), p.12915-12920

1991

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Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5Å resolution

The Journal of biological chemistry, 1991, Vol.266 (20), p.12915-12920

1991

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Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-Angstrom resolution

The Journal of biological chemistry, 1991-01, Vol.266 (20), p.12915-12920

1991

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BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2

PLoS genetics, 2018-12, Vol.14 (12), p.e1007752-e1007752

2018

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Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry

ACS chemical biology, 2018-03, Vol.13 (3), p.820-831

2018

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Selective small-molecule inhibition of an RNA structural element

Nature (London), 2015-10, Vol.526 (7575), p.672-677

2015

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Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

Communications biology, 2023-06, Vol.6 (1), p.649-649, Article 649

2023

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Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch

RNA biology, 2016-10, Vol.13 (10), p.946-954

2016

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Structural basis of CX-4945 binding to human protein kinase CK2

FEBS letters, 2011-01, Vol.585 (1), p.104-110

2011

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Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: A template-based approach

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (22), p.6178-6182

2013

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Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors

Biochemistry (Easton), 2009-03, Vol.48 (12), p.2661-2674

2009

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Differential Brain Activation During Dream Versus Story Recognition in the Medial Prefrontal Cortex: An Event-Related Functional Magnetic Resonance Imaging Study

Dreaming (New York, N.Y.), 2024-09, Vol.34 (3), p.225-241

2024

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Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 1

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.467-470

2011

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Structural insights into selective small molecule activation of PKG1α

Communications biology, 2023-07, Vol.6 (1), p.798-798, Article 798

2023

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Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 2

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.471-474

2011

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Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors

ACS medicinal chemistry letters, 2015-08, Vol.6 (8), p.942-947

2015

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Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2721-2726

2017

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Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Binational Analysis Derived From the United Kingdom and United States

The Journal of invasive cardiology, 2020-09, Vol.32 (9), p.321-329

2020

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Discovery of novel BTK inhibitors with carboxylic acids

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6), p.1471-1477

2017

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Crystal Structure of lac Repressor Core Tetramer and Its Implications for DNA Looping

Structural characterization of the complex between TIGIT and the Fab of MK684, a novel antibody for immunotherapy

Small rearrangements in structures of Fv and Fab fragments of antibody D 1.3 on antigen binding

Peptidic inhibitors of the hepatitis C virus serine protease within non-structural protein 3

Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen binding

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation

Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolution

Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5Å resolution

Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-Angstrom resolution

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2

Discovery of Selective RNA-Binding Small Molecules by Affinity-Selection Mass Spectrometry

Selective small-molecule inhibition of an RNA structural element

Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases

Atomic resolution mechanistic studies of ribocil: A highly selective unnatural ligand mimic of the E. coli FMN riboswitch

Structural basis of CX-4945 binding to human protein kinase CK2

Discovery of pyrazolo[1,5-a]pyrimidine-based Pim inhibitors: A template-based approach

Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors

Differential Brain Activation During Dream Versus Story Recognition in the Medial Prefrontal Cortex: An Event-Related Functional Magnetic Resonance Imaging Study

Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 1

Structural insights into selective small molecule activation of PKG1α

Discovery of pyrazolo[1,5-a]pyrimidine-based CHK1 inhibitors: A template-based approach—Part 2

Discovery and Structure Enabled Synthesis of 2,6-Diaminopyrimidin-4-one IRAK4 Inhibitors

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Outcomes of Percutaneous Coronary Intervention in Cardiac Transplant Patients: A Binational Analysis Derived From the United Kingdom and United States

Discovery of novel BTK inhibitors with carboxylic acids

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