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Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma

PloS one, 2015-08, Vol.10 (8), p.e0134426

2015

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Phase I Study of Vorinostat in Combination with Bortezomib for Relapsed and Refractory Multiple Myeloma

Clinical cancer research, 2009-08, Vol.15 (16), p.5250-5257

2009

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A Phase I Trial of the ABCB1 Inhibitor, Oral Valspodar, in Combination With Paclitaxel in Patients With Advanced Solid Tumors

American journal of clinical oncology, 2023-08, Vol.46 (8), p.353-359

2023

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Cisplatin Preferentially Binds Mitochondrial DNA and Voltage-Dependent Anion Channel Protein in the Mitochondrial Membrane of Head and Neck Squamous Cell Carcinoma: Possible Role in Apoptosis

Clinical cancer research, 2006-10, Vol.12 (19), p.5817-5825

2006

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In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc/Max dimerization

The Journal of pharmacology and experimental therapeutics, 2010-12, Vol.335 (3), p.715-727

2010

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Phase I Study of Vorinostat in Patients With Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study

Journal of clinical oncology, 2010-10, Vol.28 (29), p.4507-4512

2010

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Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Advanced Cancer

Clinical cancer research, 2007-03, Vol.13 (6), p.1775-1782

2007

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Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies

Clinical cancer research, 2007-06, Vol.13 (12), p.3605-3610

2007

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Phase II Study of Imatinib Mesylate Plus Hydroxyurea in Adults With Recurrent Glioblastoma Multiforme

Journal of clinical oncology, 2005-12, Vol.23 (36), p.9359-9368

2005

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Phase I Pharmacokinetic and Pharmacodynamic Study of 17-dimethylaminoethylamino-17-demethoxygeldanamycin, an Inhibitor of Heat-Shock Protein 90, in Patients With Advanced Solid Tumors

Journal of clinical oncology, 2010-03, Vol.28 (9), p.1520-1526

2010

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Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

Cancer chemotherapy and pharmacology, 2009-03, Vol.63 (4), p.615-625

2009

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Effect of St John's Wort on imatinib mesylate pharmacokinetics

Clinical pharmacology and therapeutics, 2004-10, Vol.76 (4), p.323-329

2004

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Weekly High-Dose Calcitriol and Docetaxel in Metastatic Androgen-Independent Prostate Cancer

Journal of clinical oncology, 2003-01, Vol.21 (1), p.123-128

2003

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Limited penetration of anticancer drugs through tumor tissue: A Potential cause of resistance of solid tumors to chemotherapy

Clinical cancer research, 2002-03, Vol.8 (3), p.878-884

2002

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Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of the Combination of Sorafenib and Tanespimycin

Clinical cancer research, 2010-07, Vol.16 (14), p.3795-3804

2010

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Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08)

Neuro-oncology (Charlottesville, Va.), 2009-12, Vol.11 (6), p.853-860

2009

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Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas

Clinical cancer research, 2011-03, Vol.17 (6), p.1582-1590

2011

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Phase I Pharmacokinetic-Pharmacodynamic Study of 17-(Allylamino)-17-Demethoxygeldanamycin (17AAG, NSC 330507), a Novel Inhibitor of Heat Shock Protein 90, in Patients with Refractory Advanced Cancers

Clinical cancer research, 2005-05, Vol.11 (9), p.3385-3391

2005

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Phase I-II trial of imatinib mesylate (Gleevec; STI571) in treatment of recurrent oligodendroglioma and mixed oligoastrocytoma. North central cancer treatment group study N0272 (ALLIANCE/NCCTG)

Journal of neuro-oncology, 2019-07, Vol.143 (3), p.573-581

2019

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Liquid chromatographic–mass spectrometric assay for quantitation of imatinib and its main metabolite (CGP 74588) in plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-07, Vol.791 (1), p.39-44

2003

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A Phase I, Pharmacokinetic and Pharmacodynamic Study on Vorinostat in Combination with 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Refractory Colorectal Cancer

Clinical cancer research, 2009-05, Vol.15 (9), p.3189-3195

2009

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Will Imatinib Compromise Reproductive Capacity?

The oncologist (Dayton, Ohio), 2011-10, Vol.16 (10), p.1422-1427

2011

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Imatinib-Induced Regression of AIDS-Related Kaposi's Sarcoma

Journal of clinical oncology, 2005-02, Vol.23 (5), p.982-989

2005

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Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma

Journal of acquired immune deficiency syndromes (1999), 2011-01, Vol.56 (1), p.64-68

2011

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Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma

Phase I Study of Vorinostat in Combination with Bortezomib for Relapsed and Refractory Multiple Myeloma

A Phase I Trial of the ABCB1 Inhibitor, Oral Valspodar, in Combination With Paclitaxel in Patients With Advanced Solid Tumors

Cisplatin Preferentially Binds Mitochondrial DNA and Voltage-Dependent Anion Channel Protein in the Mitochondrial Membrane of Head and Neck Squamous Cell Carcinoma: Possible Role in Apoptosis

In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of 10074-G5, a novel small-molecule inhibitor of c-Myc/Max dimerization

Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08

Phase I Study of Vorinostat in Patients With Advanced Solid Tumors and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study

Phase I Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Advanced Cancer

Phase I and Pharmacokinetic Study of Vorinostat, A Histone Deacetylase Inhibitor, in Combination with Carboplatin and Paclitaxel for Advanced Solid Malignancies

Phase II Study of Imatinib Mesylate Plus Hydroxyurea in Adults With Recurrent Glioblastoma Multiforme

Phase I Pharmacokinetic and Pharmacodynamic Study of 17-dimethylaminoethylamino-17-demethoxygeldanamycin, an Inhibitor of Heat-Shock Protein 90, in Patients With Advanced Solid Tumors

Efficacy, pharmacokinetics, tisssue distribution, and metabolism of the Myc-Max disruptor, 10058-F4 [Z,E]-5-[4-ethylbenzylidine]-2-thioxothiazolidin-4-one, in mice

Effect of St John's Wort on imatinib mesylate pharmacokinetics

Weekly High-Dose Calcitriol and Docetaxel in Metastatic Androgen-Independent Prostate Cancer

Limited penetration of anticancer drugs through tumor tissue: A Potential cause of resistance of solid tumors to chemotherapy

Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of the Combination of Sorafenib and Tanespimycin

Phase II study of imatinib mesylate for recurrent meningiomas (North American Brain Tumor Consortium study 01-08)

Phase I Study of Decitabine in Combination with Vorinostat in Patients with Advanced Solid Tumors and Non-Hodgkin's Lymphomas

Phase I Pharmacokinetic-Pharmacodynamic Study of 17-(Allylamino)-17-Demethoxygeldanamycin (17AAG, NSC 330507), a Novel Inhibitor of Heat Shock Protein 90, in Patients with Refractory Advanced Cancers

Phase I-II trial of imatinib mesylate (Gleevec; STI571) in treatment of recurrent oligodendroglioma and mixed oligoastrocytoma. North central cancer treatment group study N0272 (ALLIANCE/NCCTG)

Liquid chromatographic–mass spectrometric assay for quantitation of imatinib and its main metabolite (CGP 74588) in plasma

A Phase I, Pharmacokinetic and Pharmacodynamic Study on Vorinostat in Combination with 5-Fluorouracil, Leucovorin, and Oxaliplatin in Patients with Refractory Colorectal Cancer

Will Imatinib Compromise Reproductive Capacity?

Imatinib-Induced Regression of AIDS-Related Kaposi's Sarcoma

Phase II AIDS Malignancy Consortium trial of topical halofuginone in AIDS-related Kaposi sarcoma

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