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Reactive oxygen species at the crossroads of inflammasome and inflammation

Frontiers in physiology, 2014-09, Vol.5, p.352-352

2014

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Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine‐1‐phosphate signaling in epigenetic regulation of inflammation and gene expression

Journal of cellular biochemistry, 2018-08, Vol.119 (8), p.6337-6353

2018

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Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase

Advances in biological regulation, 2017-01, Vol.63, p.156-166

2017

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Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

BMC genomics, 2019-12, Vol.20 (1), p.984-19, Article 984

2019

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Targeting sphingosine-1-phosphate signaling in lung diseases

Pharmacology & therapeutics (Oxford), 2016-12, Vol.168, p.143-157

2016

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Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia

BMC genomics, 2017-08, Vol.18 (1), p.664-664, Article 664

2017

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Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes

Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (46), p.E6359-E6368

2015

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Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction

PloS one, 2013-05, Vol.8 (5), p.e63007

2013

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S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020-07, Vol.1865 (7), p.158681-158681, Article 158681

2020

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Neonatal therapy with PF543, a sphingosine kinase 1 inhibitor, ameliorates hyperoxia-induced airway remodeling in a murine model of bronchopulmonary dysplasia

American journal of physiology. Lung cellular and molecular physiology, 2020-09, Vol.319 (3), p.L497-L512

2020

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Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury

Thorax, 2022-01, Vol.77 (1), p.47

2022

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Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium

The Journal of biological chemistry, 2016-12, Vol.291 (53), p.27187-27203

2016

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Advancements in understanding the role of lysophospholipids and their receptors in lung disorders including bronchopulmonary dysplasia

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2020-07, Vol.1865 (7), p.158685-158685, Article 158685

2020

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Pseudomonas aeruginosa stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury

Thorax, 2019-06, Vol.74 (6), p.579

2019

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Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation

The Journal of biological chemistry, 2020-05, Vol.295 (22), p.7669-7685

2020

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Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy

Thorax, 2015-12, Vol.70 (12), p.1138-1148

2015

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Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

Cell biochemistry and biophysics, 2021-09, Vol.79 (3), p.575-592

2021

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Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium

American journal of physiology. Lung cellular and molecular physiology, 2016-08, Vol.311 (2), p.L337-L351

2016

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Sphingosine Kinase 1 Inhibitor, PF543, Blocks Inflammation and Airway Remodeling in a Murine Model of Allergic Asthma

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Δ‐2 Hexadecenal Generated from S1P by Nuclear S1P Lyase Is a Regulator of HDAC1/2 Activity and Histone Acetylation in Lung Epithelial Cells

The FASEB journal, 2019-04, Vol.33 (S1), p.489.3-489.3

2019

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Nuclear Lipid Mediators: Role of Nuclear Sphingolipids and Sphinosine-1-Phosphate Signaling in Epigenetic Regulation of Inflammation and Gene Expression

Journal of cellular biochemistry, 2018-05, Vol.119 (8), p.6337-6353

2018

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Modulation of Airway Remodeling by PF543, a Sphingosine Kinase 1 Inhibitor, in a Mouse Model of Bronchopulmonary Dysplasia

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Sphingosine kinase 1 and S1P transporter Spns2 plays important role in HGF mediated lamellipodia formation in lung endothelium

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Sphingosine Kinase‐1 inhibitor, PF‐543 ameliorates Bronchopulmonary Dysplasia in a neonatal murine model

The FASEB journal, 2017-04, Vol.31 (S1)

2017

Volltextzugriff (PDF)

Nuclear Sphingosine-1-phosphate Lyase Generated Δ2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

Cell biochemistry and biophysics, 2021-06, Vol.79 (3), p.575-592

2021

Volltextzugriff (PDF)

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Reactive oxygen species at the crossroads of inflammasome and inflammation

Nuclear lipid mediators: Role of nuclear sphingolipids and sphingosine‐1‐phosphate signaling in epigenetic regulation of inflammation and gene expression

Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase

Genetic deletion of Sphk2 confers protection against Pseudomonas aeruginosa mediated differential expression of genes related to virulent infection and inflammation in mouse lung

Targeting sphingosine-1-phosphate signaling in lung diseases

Expression profiling of genes regulated by sphingosine kinase1 signaling in a murine model of hyperoxia induced neonatal bronchopulmonary dysplasia

Reduced DOCK4 expression leads to erythroid dysplasia in myelodysplastic syndromes

Coronin 1B regulates S1P-induced human lung endothelial cell chemotaxis: role of PLD2, protein kinase C and Rac1 signal transduction

S1P and plasmalogen derived fatty aldehydes in cellular signaling and functions

Neonatal therapy with PF543, a sphingosine kinase 1 inhibitor, ameliorates hyperoxia-induced airway remodeling in a murine model of bronchopulmonary dysplasia

Sphingosine kinase 1 regulates lysyl oxidase through STAT3 in hyperoxia-mediated neonatal lung injury

Role of Sphingosine Kinase 1 and S1P Transporter Spns2 in HGF-mediated Lamellipodia Formation in Lung Endothelium

Advancements in understanding the role of lysophospholipids and their receptors in lung disorders including bronchopulmonary dysplasia

Pseudomonas aeruginosa stimulates nuclear sphingosine-1-phosphate generation and epigenetic regulation of lung inflammatory injury

Phospholipase D2 restores endothelial barrier function by promoting PTPN14-mediated VE-cadherin dephosphorylation

Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy

Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

Hyperoxia-induced p47phox activation and ROS generation is mediated through S1P transporter Spns2, and S1P/S1P1&2 signaling axis in lung endothelium

Sphingosine Kinase 1 Inhibitor, PF543, Blocks Inflammation and Airway Remodeling in a Murine Model of Allergic Asthma

Δ‐2 Hexadecenal Generated from S1P by Nuclear S1P Lyase Is a Regulator of HDAC1/2 Activity and Histone Acetylation in Lung Epithelial Cells

Nuclear Lipid Mediators: Role of Nuclear Sphingolipids and Sphinosine-1-Phosphate Signaling in Epigenetic Regulation of Inflammation and Gene Expression

Modulation of Airway Remodeling by PF543, a Sphingosine Kinase 1 Inhibitor, in a Mouse Model of Bronchopulmonary Dysplasia

Sphingosine kinase 1 and S1P transporter Spns2 plays important role in HGF mediated lamellipodia formation in lung endothelium

Sphingosine Kinase‐1 inhibitor, PF‐543 ameliorates Bronchopulmonary Dysplasia in a neonatal murine model

Nuclear Sphingosine-1-phosphate Lyase Generated Δ2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

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