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A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines

Molecular therapy, 2014-12, Vol.22 (12), p.2118-2129

2014

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Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (23), p.9619-9624

2011

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The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection

PLoS pathogens, 2021-02, Vol.17 (2), p.e1009257-e1009257

2021

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Safety, immunogenicity and efficacy of an mRNA-based COVID-19 vaccine, GLB-COV2-043, in preclinical animal models

Scientific reports, 2023-12, Vol.13 (1), p.21172-21172, Article 21172

2023

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Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa

PloS one, 2016-07, Vol.11 (7), p.e0157391-e0157391

2016

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HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells

PLoS pathogens, 2007-11, Vol.3 (11), p.e169-e169

2007

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Potent and long-lasting humoral and cellular immunity against varicella zoster virus induced by mRNA-LNP vaccine

npj vaccines, 2024-04, Vol.9 (1), p.72-72, Article 72

2024

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Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

Vaccines (Basel), 2020-07, Vol.8 (3), p.360

2020

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Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants

PloS one, 2012-04, Vol.7 (4), p.e35083-e35083

2012

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Immunogens Modeling a Fusion-Intermediate Conformation of gp41 Elicit Antibodies to the Membrane Proximal External Region of the HIV Envelope Glycoprotein

PloS one, 2015-06, Vol.10 (6), p.e0128562-e0128562

2015

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Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein

PloS one, 2013-10, Vol.8 (10), p.e76139-e76139

2013

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Characterization of Co-Formulated High-Concentration Broadly Neutralizing Anti-HIV-1 Monoclonal Antibodies for Subcutaneous Administration

Antibodies (Basel), 2020-09, Vol.9 (3), p.36

2020

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Rapid development and deployment of high‐volume vaccines for pandemic response

Journal of advanced manufacturing and processing, 2020-07, Vol.2 (3), p.e10060-n/a

2020

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An Aptamer That Neutralizes R5 Strains of Human Immunodeficiency Virus Type 1 Blocks gp120-CCR5 Interaction

Journal of Virology, 2005-11, Vol.79 (21), p.13806-13810

2005

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A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120

Virology (New York, N.Y.), 2007-04, Vol.360 (2), p.329-340

2007

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Physicochemical and functional characterization of vaccine antigens and adjuvants

Expert review of vaccines, 2014-05, Vol.13 (5), p.671-685

2014

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cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate

Biotechnology and bioengineering, 2018-04, Vol.115 (4), p.885-899

2018

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Rapid cGMP manufacturing of COVID‐19 monoclonal antibody using stable CHO cell pools

Biotechnology and bioengineering, 2022-02, Vol.119 (2), p.663-666

2022

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Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein

PloS one, 2012-01, Vol.7 (1), p.e30233-e30233

2012

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Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1

Virology (New York, N.Y.), 2007-03, Vol.360 (1), p.199-208

2007

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Role of a Putative gp41 Dimerization Domain in Human Immunodeficiency Virus Type 1 Membrane Fusion

Journal of Virology, 2010-01, Vol.84 (1), p.201-209

2010

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Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens

Journal of pharmaceutical sciences, 2019-07, Vol.108 (7), p.2264-2277

2019

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Novel adjuvants and delivery systems for enhancing immune responses induced by immunogens

Expert Review of Vaccines, 2011-02, Vol.10 (2), p.227-251

2011

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Structure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation

Biochemistry (Easton), 2009-04, Vol.48 (13), p.2915-2923

2009

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A Cationic Nanoemulsion for the Delivery of Next-generation RNA Vaccines

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection

Safety, immunogenicity and efficacy of an mRNA-based COVID-19 vaccine, GLB-COV2-043, in preclinical animal models

Generation and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern Africa

HIV-1 gp120 mannoses induce immunosuppressive responses from dendritic cells

Potent and long-lasting humoral and cellular immunity against varicella zoster virus induced by mRNA-LNP vaccine

Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants

Immunogens Modeling a Fusion-Intermediate Conformation of gp41 Elicit Antibodies to the Membrane Proximal External Region of the HIV Envelope Glycoprotein

Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein

Characterization of Co-Formulated High-Concentration Broadly Neutralizing Anti-HIV-1 Monoclonal Antibodies for Subcutaneous Administration

Rapid development and deployment of high‐volume vaccines for pandemic response

An Aptamer That Neutralizes R5 Strains of Human Immunodeficiency Virus Type 1 Blocks gp120-CCR5 Interaction

A comparative immunogenicity study in rabbits of disulfide-stabilized, proteolytically cleaved, soluble trimeric human immunodeficiency virus type 1 gp140, trimeric cleavage-defective gp140 and monomeric gp120

Physicochemical and functional characterization of vaccine antigens and adjuvants

cGMP production and analysis of BG505 SOSIP.664, an extensively glycosylated, trimeric HIV‐1 envelope glycoprotein vaccine candidate

Rapid cGMP manufacturing of COVID‐19 monoclonal antibody using stable CHO cell pools

Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein

Specific amino acids in the N-terminus of the gp41 ectodomain contribute to the stabilization of a soluble, cleaved gp140 envelope glycoprotein from human immunodeficiency virus type 1

Role of a Putative gp41 Dimerization Domain in Human Immunodeficiency Virus Type 1 Membrane Fusion

Developability Assessment of Physicochemical Properties and Stability Profiles of HIV-1 BG505 SOSIP.664 and BG505 SOSIP.v4.1-GT1.1 gp140 Envelope Glycoprotein Trimers as Candidate Vaccine Antigens

Novel adjuvants and delivery systems for enhancing immune responses induced by immunogens

Structure of the HIV-1 gp41 Membrane-Proximal Ectodomain Region in a Putative Prefusion Conformation

Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site

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