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Daf-16 mediated repression of cytosolic ribosomal protein genes facilitates a hypoxia sensitive to hypoxia resistant transformation in long-lived germline mutants

PLoS genetics, 2022-05, Vol.18 (5), p.e1009672-e1009672

2022

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The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters

Trends in pharmacological sciences (Regular ed.), 2018-07, Vol.39 (7), p.635-647

2018

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Characterizing bourbon whiskey via the combination of LC-MS and GC–MS based molecular fingerprinting

Food chemistry, 2023-10, Vol.423, p.136311-136311, Article 136311

2023

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A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases

Nature communications, 2017-09, Vol.8 (1), p.538-11, Article 538

2017

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Metallo-β-lactamases: Novel Weaponry for Antibiotic Resistance in Bacteria

Accounts of chemical research, 2006-10, Vol.39 (10), p.721-728

2006

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Multiple and Optimal Screening Subset: a method selecting global characteristic congeners for robust foodomics analysis

Briefings in bioinformatics, 2024-01, Vol.25 (2)

2024

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Hypoxia-induced mitochondrial stress granules

Cell death & disease, 2023-07, Vol.14 (7), p.448-448, Article 448

2023

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Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase‑1

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7267-7283

2017

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Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity

The Journal of biological chemistry, 2018-08, Vol.293 (32), p.12606-12618

2018

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Mitochondrial Proteostatic Collapse Leads to Hypoxic Injury

Current biology, 2015-08, Vol.25 (16), p.2171-2176

2015

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Effect of the mitochondrial unfolded protein response on hypoxic death and mitochondrial protein aggregation

Cell death & disease, 2021-07, Vol.12 (7), p.711-711, Article 711

2021

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Ageing and hypoxia cause protein aggregation in mitochondria

Cell death and differentiation, 2017-10, Vol.24 (10), p.1730-1738

2017

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Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase‑1 in Bacteria Using a Reversible Fluorescent Probe

Journal of the American Chemical Society, 2021-06, Vol.143 (22), p.8314-8323

2021

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Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM‑1

Journal of the American Chemical Society, 2014-05, Vol.136 (20), p.7273-7285

2014

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Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1

Biochemistry (Easton), 2012-05, Vol.51 (18), p.3839-3847

2012

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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

European journal of medicinal chemistry, 2021-12, Vol.226, p.113873-113873, Article 113873

2021

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Targeting metallo-carbapenemases via modulation of electronic properties of cephalosporins

Biochemical journal, 2014-12, Vol.464 (2), p.271-279

2014

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Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery

Molecular and Cellular Biology, 2010-11, Vol.30 (21), p.5033-5042

2010

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The directed evolution of NDM-1

Antimicrobial agents and chemotherapy, 2023-11, Vol.67 (11), p.e0071423-e0071423

2023

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Fragment‐based screening and hit‐based substructure search: Rapid discovery of 8‐hydroxyquinoline‐7‐carboxylic acid as a low‐cytotoxic, nanomolar metallo β‐lactamase inhibitor

Chemical biology & drug design, 2021-10, Vol.98 (4), p.481-492

2021

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A screen for protective drugs against delayed hypoxic injury

PloS one, 2017-04, Vol.12 (4), p.e0176061-e0176061

2017

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Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants

Antimicrobial agents and chemotherapy, 2021-03, Vol.65 (4)

2021

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Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase

Journal of chemical information and modeling, 2024-05, Vol.64 (10), p.3977-3991

2024

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Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1

Journal of inorganic biochemistry, 2020-09, Vol.210, p.111123-111123, Article 111123

2020

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Daf-16 mediated repression of cytosolic ribosomal protein genes facilitates a hypoxia sensitive to hypoxia resistant transformation in long-lived germline mutants

The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters

Characterizing bourbon whiskey via the combination of LC-MS and GC–MS based molecular fingerprinting

A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases

Metallo-β-lactamases: Novel Weaponry for Antibiotic Resistance in Bacteria

Multiple and Optimal Screening Subset: a method selecting global characteristic congeners for robust foodomics analysis

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates

Hypoxia-induced mitochondrial stress granules

Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase‑1

Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity

Mitochondrial Proteostatic Collapse Leads to Hypoxic Injury

Effect of the mitochondrial unfolded protein response on hypoxic death and mitochondrial protein aggregation

Ageing and hypoxia cause protein aggregation in mitochondria

Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase‑1 in Bacteria Using a Reversible Fluorescent Probe

Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM‑1

Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

Targeting metallo-carbapenemases via modulation of electronic properties of cephalosporins

Protein Misfolding Induces Hypoxic Preconditioning via a Subset of the Unfolded Protein Response Machinery

The directed evolution of NDM-1

Fragment‐based screening and hit‐based substructure search: Rapid discovery of 8‐hydroxyquinoline‐7‐carboxylic acid as a low‐cytotoxic, nanomolar metallo β‐lactamase inhibitor

A screen for protective drugs against delayed hypoxic injury

Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants

Machine Learning Models Identify Inhibitors of New Delhi Metallo-β-lactamase

Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1

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