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Development of original metabolically stable apelin‐17 analogs with diuretic and cardiovascular effects

The FASEB journal, 2017-02, Vol.31 (2), p.687-700

2017

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Involvement of arginine 878 together with Ca2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

PloS one, 2017-09, Vol.12 (9), p.e0184237

2017

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Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders

Frontiers in endocrinology (Lausanne), 2017-05, Vol.8, p.120-120

2017

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Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer

Communications biology, 2021-09, Vol.4 (1), p.1062-1062, Article 1062

2021

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Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice

Frontiers in cellular neuroscience, 2022-11, Vol.16, p.1076599-1076599

2022

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Ackr3-Venus knock-in mouse lights up brain vasculature

Molecular brain, 2021-09, Vol.14 (1), p.151-23, Article 151

2021

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Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies

Communications chemistry, 2023-07, Vol.6 (1), p.160-160, Article 160

2023

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Elabela/Toddler and apelin bind differently to the apelin receptor

The FASEB journal, 2020-06, Vol.34 (6), p.7989-8000

2020

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Crucial role of the orexin‐B C‐terminus in the induction of OX1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

British journal of pharmacology, 2015-11, Vol.172 (21), p.5211-5223

2015

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Monitoring Signalling and Trafficking of Neurotensin Type 1 Receptor in Animal Model using Fluorescent‐based Methods

The FASEB journal, 2019-04, Vol.33 (S1), p.502.4-502.4

2019

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Structural insight into the catalytic mechanism and inhibitor binding of aminopeptidase A

Biochemical journal, 2020-11, Vol.477 (21), p.4133-4148

2020

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Crucial role of the orexin‐B C‐terminus in the induction of OX 1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

British journal of pharmacology, 2015-11, Vol.172 (21), p.5211-5223

2015

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Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (26), p.13006-13015

2019

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Abstract 5299: The C-terminus of orexin plays a crucial role in the cellular apoptosis induction mediated by OX1 receptor

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5299-5299

2014

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Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.602-615

2021

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Size-Reduced Macrocyclic Analogues of [Pyr1]‑apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.531-551

2022

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New structural insights into the apelin receptor: identification of key residues for apelin binding

The FASEB journal, 2015-01, Vol.29 (1), p.314-322

2015

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Involvement of arginine 878 together with Ca.sup.2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

PloS one, 2017-09, Vol.12 (9), p.e0184237

2017

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Involvement of arginine 878 together with Ca2+ in aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

PloS one, 2017-09, Vol.12 (9)

2017

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Size-Reduced Macrocyclic Analogues of [Pyr 1 ]-apelin-13 Showing Negative Gα 12 Bias Still Produce Prolonged Cardiac Effects

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.531-551

2022

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Sa2023 Importance of the Orexin-B C-Terminal End in the Cellular Apoptosis Induction Mediated by Ox1 Receptor

Gastroenterology (New York, N.Y. 1943), 2013-05, Vol.144 (5), p.S-361-S-362

2013

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Constraining the Side Chain of C‑Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile

Journal of medicinal chemistry, 2021-05, Vol.64 (9), p.5345-5364

2021

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Recurrent PRKAR1A Mutation in Acrodysostosis with Hormone Resistance

The New England journal of medicine, 2011-06, Vol.364 (23), p.2218-2226

2011

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In vitro , in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma

Oncotarget, 2018-01, Vol.9 (6), p.6952-6967

2018

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Development of original metabolically stable apelin‐17 analogs with diuretic and cardiovascular effects

Involvement of arginine 878 together with Ca2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders

Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer

Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice

Ackr3-Venus knock-in mouse lights up brain vasculature

Structure, dynamics and transferability of the metal-dependent polyhistidine tetramerization motif TetrHis for single-chain Fv antibodies

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus

Elabela/Toddler and apelin bind differently to the apelin receptor

Crucial role of the orexin‐B C‐terminus in the induction of OX1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

Monitoring Signalling and Trafficking of Neurotensin Type 1 Receptor in Animal Model using Fluorescent‐based Methods

Structural insight into the catalytic mechanism and inhibitor binding of aminopeptidase A

Crucial role of the orexin‐B C‐terminus in the induction of OX 1 receptor‐mediated apoptosis: analysis by alanine scanning, molecular modelling and site‐directed mutagenesis

Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs

Abstract 5299: The C-terminus of orexin plays a crucial role in the cellular apoptosis induction mediated by OX1 receptor

Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor

Size-Reduced Macrocyclic Analogues of [Pyr1]‑apelin-13 Showing Negative Gα12 Bias Still Produce Prolonged Cardiac Effects

New structural insights into the apelin receptor: identification of key residues for apelin binding

Involvement of arginine 878 together with Ca.sup.2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

Involvement of arginine 878 together with Ca2+ in aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

Size-Reduced Macrocyclic Analogues of [Pyr 1 ]-apelin-13 Showing Negative Gα 12 Bias Still Produce Prolonged Cardiac Effects

Sa2023 Importance of the Orexin-B C-Terminal End in the Cellular Apoptosis Induction Mediated by Ox1 Receptor

Constraining the Side Chain of C‑Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile

Recurrent PRKAR1A Mutation in Acrodysostosis with Hormone Resistance

In vitro , in vivo and ex vivo demonstration of the antitumoral role of hypocretin-1/orexin-A and almorexant in pancreatic ductal adenocarcinoma

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