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The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders

Annals of the New York Academy of Sciences, 2019-11, Vol.1455 (1), p.12-33

2019

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Elabela/Toddler and apelin bind differently to the apelin receptor

The FASEB journal, 2020-06, Vol.34 (6), p.7989-8000

2020

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Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure

Pharmacological reviews, 2019-10, Vol.71 (4), p.539-570

2019

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The role of the brain renin-angiotensin system in hypertension: implications for new treatment

Progress in neurobiology, 2011-10, Vol.95 (2), p.89-103

2011

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Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure

Journal of neurochemistry, 2004-09, Vol.90 (6), p.1290-1301

2004

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New structural insights into the apelin receptor: identification of key residues for apelin binding

The FASEB journal, 2015-01, Vol.29 (1), p.314-322

2015

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Effects of firibastat in combination with enalapril and hydrochlorothiazide on blood pressure and vasopressin release in hypertensive DOCA-salt rats

Biomedicine & pharmacotherapy, 2021-08, Vol.140, p.111682-111682, Article 111682

2021

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A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

Nature communications, 2021-01, Vol.12 (1), p.305-14, Article 305

2021

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Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor

International journal of molecular sciences, 2023-02, Vol.24 (3), p.2330

2023

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Apelin and Vasopressin: The Yin and Yang of Water Balance

Frontiers in endocrinology (Lausanne), 2021-11, Vol.12, p.735515-735515

2021

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On Methods for the Measurement of the Apelin Receptor Ligand Apelin

Scientific reports, 2022-05, Vol.12 (1), p.7763-7763, Article 7763

2022

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Involvement of arginine 878 together with Ca2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

PloS one, 2017-09, Vol.12 (9), p.e0184237

2017

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Development of original metabolically stable apelin‐17 analogs with diuretic and cardiovascular effects

The FASEB journal, 2017-02, Vol.31 (2), p.687-700

2017

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LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism

Frontiers in pharmacology, 2021-07, Vol.12, p.715095-715095

2021

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Apelin, a Potent Diuretic Neuropeptide Counteracting Vasopressin Actions through Inhibition of Vasopressin Neuron Activity and Vasopressin Release

Proceedings of the National Academy of Sciences - PNAS, 2004-07, Vol.101 (28), p.10464-10469

2004

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Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders

Frontiers in endocrinology (Lausanne), 2017-05, Vol.8, p.120-120

2017

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Apelin and Vasopressin: Two Work Better than One

Journal of neuroendocrinology, 2012-07, Vol.24 (7), p.1085-1086

2012

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Effect of apelin on glomerular hemodynamic function in the rat kidney

Kidney international, 2008-08, Vol.74 (4), p.486-494

2008

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Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist

The FASEB journal, 2010-05, Vol.24 (5), p.1506-1517

2010

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Reciprocal Regulation of Plasma Apelin and Vasopressin by Osmotic Stimuli

Journal of the American Society of Nephrology, 2008-05, Vol.19 (5), p.1015-1024

2008

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Metabolically stable apelin-analogues, incorporating cyclohexylalanine and homoarginine, as potent apelin receptor activators

RSC medicinal chemistry, 2021-08, Vol.12 (8), p.142-1413

2021

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Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging

Chemistry : a European journal, 2016-01, Vol.22 (4), p.1399-1405

2016

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A Time‐Resolved FRET Cell‐Based Binding Assay for the Apelin Receptor

ChemMedChem, 2017-06, Vol.12 (12), p.925-931

2017

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Apelin in the control of body fluid homeostasis and cardiovascular functions

Current pharmaceutical design, 2012-02, Vol.18 (6), p.789

2012

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Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging

PloS one, 2014-02, Vol.9 (2), p.e87421

2014

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The apelinergic system: a perspective on challenges and opportunities in cardiovascular and metabolic disorders

Elabela/Toddler and apelin bind differently to the apelin receptor

Novel Therapeutic Approaches Targeting the Renin-Angiotensin System and Associated Peptides in Hypertension and Heart Failure

The role of the brain renin-angiotensin system in hypertension: implications for new treatment

Functional dissociation of apelin receptor signaling and endocytosis: implications for the effects of apelin on arterial blood pressure

New structural insights into the apelin receptor: identification of key residues for apelin binding

Effects of firibastat in combination with enalapril and hydrochlorothiazide on blood pressure and vasopressin release in hypertensive DOCA-salt rats

A metabolically stable apelin-17 analog decreases AVP-induced antidiuresis and improves hyponatremia

Characterization of the First Animal Toxin Acting as an Antagonist on AT1 Receptor

Apelin and Vasopressin: The Yin and Yang of Water Balance

On Methods for the Measurement of the Apelin Receptor Ligand Apelin

Involvement of arginine 878 together with Ca2+ in mouse aminopeptidase A substrate specificity for N-terminal acidic amino-acid residues

Development of original metabolically stable apelin‐17 analogs with diuretic and cardiovascular effects

LIT01-196, a Metabolically Stable Apelin-17 Analog, Normalizes Blood Pressure in Hypertensive DOCA-Salt Rats via a NO Synthase-dependent Mechanism

Apelin, a Potent Diuretic Neuropeptide Counteracting Vasopressin Actions through Inhibition of Vasopressin Neuron Activity and Vasopressin Release

Role of the Vasopressin/Apelin Balance and Potential Use of Metabolically Stable Apelin Analogs in Water Metabolism Disorders

Apelin and Vasopressin: Two Work Better than One

Effect of apelin on glomerular hemodynamic function in the rat kidney

Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist

Reciprocal Regulation of Plasma Apelin and Vasopressin by Osmotic Stimuli

Metabolically stable apelin-analogues, incorporating cyclohexylalanine and homoarginine, as potent apelin receptor activators

Convenient Access to Fluorescent Probes by Chemoselective Acylation of Hydrazinopeptides: Application to the Synthesis of the First Far-Red Ligand for Apelin Receptor Imaging

A Time‐Resolved FRET Cell‐Based Binding Assay for the Apelin Receptor

Apelin in the control of body fluid homeostasis and cardiovascular functions

Mechanisms involved in dual vasopressin/apelin neuron dysfunction during aging

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