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Lead Optimization Using Matched Molecular Pairs: Inclusion of Contextual Information for Enhanced Prediction of hERG Inhibition, Solubility, and Lipophilicity

Journal of chemical information and modeling, 2010-10, Vol.50 (10), p.1872-1886

2010

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Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7381-7399

2015

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Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.714-746

2020

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A Turing Test for Molecular Generators

Journal of medicinal chemistry, 2020-10, Vol.63 (20), p.11964-11971

2020

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Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4237-4241

2008

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A novel nonintrusive method to resolve the thermal dome effect of pyranometers: Radiometric calibration and implications

Journal of Geophysical Research: Atmospheres, 2011-12, Vol.116 (D24), p.n/a

2011

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Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3‑Kinase δ through a Deconstruction and Regrowth Approach

Journal of medicinal chemistry, 2018-12, Vol.61 (24), p.11061-11073

2018

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Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease

Journal of medicinal chemistry, 2016-08, Vol.59 (15), p.7239-7251

2016

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Ultracool spectroscopic outliers in Gaia DR3

Monthly notices of the Royal Astronomical Society, 2024-01, Vol.527 (1), p.1521-1533

2024

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Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor

Proceedings of the National Academy of Sciences - PNAS, 2009-10, Vol.106 (43), p.18114-18119

2009

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Optimized Chemical Probes for REV-ERBα

Journal of medicinal chemistry, 2013-06, Vol.56 (11), p.4729-4737

2013

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UGPS J194310+183851: an unusual optical and X-ray faint cataclysmic variable?

Monthly notices of the Royal Astronomical Society, 2022-07, Vol.514 (4), p.6002-6010

2022

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Synthesis of Arrays Using Low Molecular Weight MPEG-Assisted Mitsunobu Reaction

ACS combinatorial science, 2011-05, Vol.13 (3), p.280-285

2011

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Serendipitous discovery of a dusty disc around WDJ181417.84−735459.83

Monthly notices of the Royal Astronomical Society, 2021-03, Vol.501 (3), p.3916-3925

2021

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N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4363-4368

2007

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Management of Deeply Infiltrating Endometriosis Involving the Rectum

Diseases of the colon & rectum, 2012-09, Vol.55 (9), p.925-931

2012

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Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1126-1133

2011

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The verification of periodicity with the use of recurrent neural networks

RAS techniques and instruments, 2024-01, Vol.3 (1), p.224-233

2024

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Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (1), p.158-162

2009

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Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease

Journal of medicinal chemistry, 2016-10, Vol.59 (20), p.9574-9574

2016

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Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease

Journal of medicinal chemistry, 2016-09, Vol.59 (17), p.8148-8148

2016

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Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)

Angewandte Chemie (International ed.), 2010-10, Vol.49 (44), p.8082-8091

2010

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Delineating sociodemographic, medical and quality of life factors associated with psychological distress in individuals with endometriosis

Human reproduction (Oxford), 2021-07, Vol.36 (8), p.2170-2180

2021

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Adverse drug reaction-related hospitalizations of nursing facility patients : A 4-year study

Southern medical journal (Birmingham, Ala.), 1999-05, Vol.92 (5), p.485-490

COOPER, J. W

1999

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Body image, self-compassion, and sexual distress in individuals living with endometriosis

Journal of psychosomatic research, 2023-04, Vol.167, p.111197-111197, Article 111197

2023

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Lead Optimization Using Matched Molecular Pairs: Inclusion of Contextual Information for Enhanced Prediction of hERG Inhibition, Solubility, and Lipophilicity

Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease

Discovery of a Bromodomain and Extraterminal Inhibitor with a Low Predicted Human Dose through Synergistic Use of Encoded Library Technology and Fragment Screening

A Turing Test for Molecular Generators

Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors

A novel nonintrusive method to resolve the thermal dome effect of pyranometers: Radiometric calibration and implications

Discovery of Potent, Efficient, and Selective Inhibitors of Phosphoinositide 3‑Kinase δ through a Deconstruction and Regrowth Approach

Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease

Ultracool spectroscopic outliers in Gaia DR3

Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor

Optimized Chemical Probes for REV-ERBα

UGPS J194310+183851: an unusual optical and X-ray faint cataclysmic variable?

Synthesis of Arrays Using Low Molecular Weight MPEG-Assisted Mitsunobu Reaction

Serendipitous discovery of a dusty disc around WDJ181417.84−735459.83

N-4-Pyrimidinyl-1H-indazol-4-amine inhibitors of Lck: Indazoles as phenol isosteres with improved pharmacokinetics

Management of Deeply Infiltrating Endometriosis Involving the Rectum

Discovery of a potent series of non-steroidal non α-trifluoromethyl carbinol glucocorticoid receptor agonists with reduced lipophilicity

The verification of periodicity with the use of recurrent neural networks

Aryl aminopyrazole benzamides as oral non-steroidal selective glucocorticoid receptor agonists

Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease

Correction to Evolution of a Novel, Orally Bioavailable Series of PI3Kδ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease

Factors Determining the Selection of Organic Reactions by Medicinal Chemists and the Use of These Reactions in Arrays (Small Focused Libraries)

Delineating sociodemographic, medical and quality of life factors associated with psychological distress in individuals with endometriosis

Adverse drug reaction-related hospitalizations of nursing facility patients : A 4-year study

Body image, self-compassion, and sexual distress in individuals living with endometriosis

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