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HIV-1 variants are archived throughout infection and persist in the reservoir

PLoS pathogens, 2020-06, Vol.16 (6), p.e1008378-e1008378

2020

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Selection bias at the heterosexual HIV-1 transmission bottleneck

Science (American Association for the Advancement of Science), 2014-07, Vol.345 (6193), p.178-178

2014

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Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis

PLoS pathogens, 2012-11, Vol.8 (11), p.e1003041-e1003041

2012

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Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade

Nature communications, 2024-04, Vol.15 (1), p.2853-16, Article 2853

2024

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Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4⁺ T cells, and disease progression

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (12), p.E1480-E1489

2015

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Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression

The Journal of experimental medicine, 2016-09, Vol.213 (10), p.2049-2063

2016

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Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis

PLoS pathogens, 2019-08, Vol.15 (8), p.e1007981-e1007981

2019

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Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients

PLoS pathogens, 2015-01, Vol.11 (1), p.e1004565-e1004565

2015

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Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection

Frontiers in immunology, 2021-05, Vol.12, p.667393-667393

2021

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Impact of HLA-B81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity

Journal of Virology, 2012-03, Vol.86 (6), p.3193-3199

2012

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Of mice, or men: TLR4 signaling in HIV pathogenesis

Journal of leukocyte biology, 2023-05, Vol.113 (5), p.415-417

2023

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Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity

Retrovirology, 2011-05, Vol.8 (1), p.37-37, Article 37

2011

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Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo

Nature medicine, 2020-11, Vol.26 (11), p.1776-1787

2020

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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

Cancer cell, 2023-04, Vol.41 (4), p.740-756.e10

2023

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A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope

Journal of virology, 2024-03, Vol.98 (3), p.e0172023

2024

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Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia

Journal of virology, 2019-10, Vol.93 (20)

2019

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An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

Cancer discovery, 2023-07, Vol.13 (7), p.1696-1719

2023

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HLA Class I Downregulation by HIV-1 Variants from Subtype C Transmission Pairs

Journal of virology, 2018-04, Vol.92 (7)

2018

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Poly I:C and STING agonist‐primed DC increase lymphoid tissue polyfunctional HIV‐1‐specific CD8+ T cells and limit CD4+ T‐cell loss in BLT mice

European journal of immunology, 2022-03, Vol.52 (3), p.447-461

2022

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Interferon-I: The Pièce de Résistance of HIV-1 Transmission?

Trends in microbiology (Regular ed.), 2017-05, Vol.25 (5), p.332-334

2017

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Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased cloning

Virology (New York, N.Y.), 2014-11, Vol.468, p.454-461

2014

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The African-centric P47S Variant of TP53 Confers Immune Dysregulation and Impaired Response to Immune Checkpoint Inhibition

Cancer research communications, 2023-07, Vol.3 (7), p.1200-1211

2023

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A restriction enzyme based cloning method to assess the in vitro replication capacity of HIV-1 subtype C Gag-MJ4 chimeric viruses

Journal of visualized experiments, 2014-08 (90)

2014

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Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency

Scientific reports, 2016-11, Vol.6 (1), p.38153, Article 38153

2016

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HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck

Science (American Association for the Advancement of Science), 2014-07, Vol.345 (6193), p.1254031-1254031

2014

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HIV-1 variants are archived throughout infection and persist in the reservoir

Selection bias at the heterosexual HIV-1 transmission bottleneck

Role of transmitted Gag CTL polymorphisms in defining replicative capacity and early HIV-1 pathogenesis

Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade

Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4⁺ T cells, and disease progression

Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression

Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients

Innate Immune Reconstitution in Humanized Bone Marrow-Liver-Thymus (HuBLT) Mice Governs Adaptive Cellular Immune Function and Responses to HIV-1 Infection

Impact of HLA-B81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity

Of mice, or men: TLR4 signaling in HIV pathogenesis

Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity

Dual CD4-based CAR T cells with distinct costimulatory domains mitigate HIV pathogenesis in vivo

Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

A VRC13-like bNAb response is associated with complex escape pathways in HIV-1 envelope

Immunization of BLT Humanized Mice Redirects T Cell Responses to Gag and Reduces Acute HIV-1 Viremia

An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression

HLA Class I Downregulation by HIV-1 Variants from Subtype C Transmission Pairs

Poly I:C and STING agonist‐primed DC increase lymphoid tissue polyfunctional HIV‐1‐specific CD8+ T cells and limit CD4+ T‐cell loss in BLT mice

Interferon-I: The Pièce de Résistance of HIV-1 Transmission?

Particle infectivity of HIV-1 full-length genome infectious molecular clones in a subtype C heterosexual transmission pair following high fidelity amplification and unbiased cloning

The African-centric P47S Variant of TP53 Confers Immune Dysregulation and Impaired Response to Immune Checkpoint Inhibition

A restriction enzyme based cloning method to assess the in vitro replication capacity of HIV-1 subtype C Gag-MJ4 chimeric viruses

Wide variation in susceptibility of transmitted/founder HIV-1 subtype C Isolates to protease inhibitors and association with in vitro replication efficiency

HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck

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