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Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis

Annual review of nutrition, 2021-10, Vol.41 (1), p.19-47

2021

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Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

Cell metabolism, 2015-10, Vol.22 (4), p.682-694

2015

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Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

Cell metabolism, 2011-12, Vol.14 (6), p.804-810

2011

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CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity

Nucleic acids research, 2015-12, Vol.43 (22), p.e157-e157

2015

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Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation

Cell metabolism, 2017-08, Vol.26 (2), p.394-406.e6

2017

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High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

Genome research, 2015-07, Vol.25 (7), p.1030-1042

2015

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Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis

Cell metabolism, 2015-10, Vol.22 (4), p.669-681

2015

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Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

PLoS genetics, 2022-02, Vol.18 (2), p.e1010067-e1010067

2022

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FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia

Cell metabolism, 2017-11, Vol.26 (5), p.709-718.e3

2017

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Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish

Nature communications, 2023-08, Vol.14 (1), p.4942-4942, Article 4942

2023

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A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish

Nature protocols, 2016-12, Vol.11 (12), p.2357-2375

2016

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Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4447-4462

2015

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The Genetic Basis of Morphological Diversity in Domesticated Goldfish

Current biology, 2020-06, Vol.30 (12), p.2260-2274.e6

2020

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Krebs takes a turn at cell differentiation

Cell metabolism, 2022-05, Vol.34 (5), p.658-660

2022

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Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver[S]

Journal of lipid research, 2012-06, Vol.53 (6), p.1080-1092

2012

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Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver

Cell metabolism, 2019-06, Vol.29 (6), p.1291-1305.e8

2019

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A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice[S]

Journal of lipid research, 2014-12, Vol.55 (12), p.2541-2553

2014

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Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs

Genetics (Austin), 2015-06, Vol.200 (2), p.431-441

2015

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Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver

JCI insight, 2019-06, Vol.5 (11)

2019

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A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies

Frontiers in neural circuits, 2015-11, Vol.9, p.78-78

2015

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FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

Cell metabolism, 2011-06, Vol.13 (6), p.729-738

2011

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FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10853-10858

2009

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INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis

Metabolic engineering, 2022-01, Vol.69, p.275-285

2022

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Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy

The Journal of clinical investigation, 2015-02, Vol.125 (2), p.870-880

2015

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Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

The American journal of clinical nutrition, 2011-05, Vol.93 (5), p.1048-1052

2011

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Ins and Outs of the TCA Cycle: The Central Role of Anaplerosis

Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

CRISPR-STAT: an easy and reliable PCR-based method to evaluate target-specific sgRNA activity

Acetyl CoA Carboxylase Inhibition Reduces Hepatic Steatosis but Elevates Plasma Triglycerides in Mice and Humans: A Bedside to Bench Investigation

High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9

Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis

Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development

FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia

Ontogenetically distinct neutrophils differ in function and transcriptional profile in zebrafish

A high-throughput functional genomics workflow based on CRISPR/Cas9-mediated targeted mutagenesis in zebrafish

Mitochondrial metabolism mediates oxidative stress and inflammation in fatty liver

The Genetic Basis of Morphological Diversity in Domesticated Goldfish

Krebs takes a turn at cell differentiation

Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver[S]

Pyruvate-Carboxylase-Mediated Anaplerosis Promotes Antioxidant Capacity by Sustaining TCA Cycle and Redox Metabolism in Liver

A high-fat diet suppresses de novo lipogenesis and desaturation but not elongation and triglyceride synthesis in mice[S]

Multiplex Conditional Mutagenesis Using Transgenic Expression of Cas9 and sgRNAs

Impaired ketogenesis and increased acetyl-CoA oxidation promote hyperglycemia in human fatty liver

A 3D Searchable Database of Transgenic Zebrafish Gal4 and Cre Lines for Functional Neuroanatomy Studies

FGF15/19 Regulates Hepatic Glucose Metabolism by Inhibiting the CREB-PGC-1α Pathway

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

INCA 2.0: A tool for integrated, dynamic modeling of NMR- and MS-based isotopomer measurements and rigorous metabolic flux analysis

Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy

Short-term weight loss and hepatic triglyceride reduction: evidence of a metabolic advantage with dietary carbohydrate restriction

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