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STING and the innate immune response to nucleic acids in the cytosol

Nature immunology, 2013-01, Vol.14 (1), p.19

2013

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The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING

Cell reports (Cambridge), 2013-05, Vol.3 (5), p.1355-1361

2013

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STING is a direct innate immune sensor of cyclic di-GMP

Nature (London), 2011-10, Vol.478 (7370), p.515-518

2011

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Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleos(t)ide therapy

PloS one, 2022-04, Vol.17 (4), p.e0262516-e0262516

2022

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Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

Nature communications, 2016-02, Vol.7 (1), p.10680-10680, Article 10680

2016

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Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

The Journal of immunology (1950), 2013-05, Vol.190 (10), p.5216-5225

2013

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STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection

mBio, 2013-07, Vol.4 (3), p.e00018-e00013

2013

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Characterization of Hepatitis B Precore/Core-Related Antigens

Journal of virology, 2021-01, Vol.95 (3)

2021

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Vibrio VopQ induces PI3-kinase-independent autophagy and antagonizes phagocytosis

Molecular microbiology, 2009-08, Vol.73 (4), p.639-649

2009

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The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection

PloS one, 2017-01, Vol.12 (1), p.e0169648-e0169648

2017

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Targeting lipid biosynthesis pathways for hepatitis B virus cure

PloS one, 2022-08, Vol.17 (8)

2022

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Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis

Proceedings of the National Academy of Sciences - PNAS, 2008-08, Vol.105 (34), p.12497-12502

2008

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Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR

Nature communications, 2023-01, Vol.14 (1), p.471-14, Article 471

2023

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Targeting lipid biosynthesis pathways for hepatitis B virus cure

PloS one, 2022-08, Vol.17 (8), p.e0270273-e0270273

2022

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Vibrio effector protein VopQ inhibits fusion of V-ATPase–containing membranes

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (1), p.100-105

2015

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Arp2/3-independent assembly of actin by Vibrio type III effector VopL

Proceedings of the National Academy of Sciences - PNAS, 2007-10, Vol.104 (43), p.17117-17122

2007

Volltextzugriff (PDF)

Inhibition of MAPK Signaling Pathways by VopA from Vibrio parahaemolyticus

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.51953-51957

2004

Volltextzugriff (PDF)

1338 Crystallography-guided characterization of novel cytosolic DNase 3’ repair exonuclease 1 (TREX1) inhibitors

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1492-A1492

2023

Volltextzugriff (PDF)

Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation

Frontiers in molecular biosciences, 2019-08, Vol.6, p.67-67

2019

Volltextzugriff (PDF)

Not without cause: Vibrio parahaemolyticus induces acute autophagy and cell death

Autophagy, 2009-01, Vol.5 (1), p.100-102

2009

Volltextzugriff (PDF)

The RACK1 Homologue from Trypanosoma brucei Is Required for the Onset and Progression of Cytokinesis

The Journal of biological chemistry, 2006-04, Vol.281 (14), p.9781-9790

2006

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Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways

PloS one, 2008-01, Vol.3 (1), p.e1375-e1375

2008

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Generation of an HBV core phenotyping assay for evaluating HBV capsid compounds

Journal of virological methods, 2021-06, Vol.292, p.114117-114117, Article 114117

2021

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Intrahepatic transcriptional profiling demonstrates preclinical models of chronic hepatitis B resemble different stages of natural history in humans

Journal of hepatology, 2022-07, Vol.77, p.S251

2022

Volltextzugriff (PDF)

Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleoside therapy

PloS one, 2022-04, Vol.17 (4), p.e0262516

2022

Volltextzugriff (PDF)

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STING and the innate immune response to nucleic acids in the cytosol

The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING

STING is a direct innate immune sensor of cyclic di-GMP

Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleos(t)ide therapy

Influenza A virus targets a cGAS-independent STING pathway that controls enveloped RNA viruses

Mouse, but not human STING, binds and signals in response to the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid

STING-dependent recognition of cyclic di-AMP mediates type I interferon responses during Chlamydia trachomatis infection

Characterization of Hepatitis B Precore/Core-Related Antigens

Vibrio VopQ induces PI3-kinase-independent autophagy and antagonizes phagocytosis

The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection

Targeting lipid biosynthesis pathways for hepatitis B virus cure

Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis

Molecular elucidation of drug-induced abnormal assemblies of the hepatitis B virus capsid protein by solid-state NMR

Targeting lipid biosynthesis pathways for hepatitis B virus cure

Vibrio effector protein VopQ inhibits fusion of V-ATPase–containing membranes

Arp2/3-independent assembly of actin by Vibrio type III effector VopL

Inhibition of MAPK Signaling Pathways by VopA from Vibrio parahaemolyticus

1338 Crystallography-guided characterization of novel cytosolic DNase 3’ repair exonuclease 1 (TREX1) inhibitors

Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation

Not without cause: Vibrio parahaemolyticus induces acute autophagy and cell death

The RACK1 Homologue from Trypanosoma brucei Is Required for the Onset and Progression of Cytokinesis

Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways

Generation of an HBV core phenotyping assay for evaluating HBV capsid compounds

Intrahepatic transcriptional profiling demonstrates preclinical models of chronic hepatitis B resemble different stages of natural history in humans

Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleoside therapy

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