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Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53

Proceedings of the National Academy of Sciences - PNAS, 2007-11, Vol.104 (47), p.18613-18618

2007

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Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers

Carcinogenesis (New York), 2007-02, Vol.28 (2), p.289-298

2007

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A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

Clinical cancer research, 2017-12, Vol.23 (24), p.7490-7497

2017

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Phase Ib clinical trial of the anti-frizzled antibody vantictumab (OMP-18R5) plus paclitaxel in patients with locally advanced or metastatic HER2-negative breast cancer

Breast cancer research and treatment, 2020-11, Vol.184 (1), p.53-62

2020

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Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer

Clinical cancer research, 2020-10, Vol.26 (20), p.5348-5357

2020

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p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5

International journal of cancer, 2011-01, Vol.128 (2), p.304-318

2011

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Choosing where to look next in a mutation sequence space: Active Learning of informative p53 cancer rescue mutants

Bioinformatics, 2007-07, Vol.23 (13), p.i104-i114

2007

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Phosphoinositide 3-Kinase (PI3K) Pathway Alterations Are Associated with Histologic Subtypes and Are Predictive of Sensitivity to PI3K Inhibitors in Lung Cancer Preclinical Models

Clinical cancer research, 2012-12, Vol.18 (24), p.6771-6783

2012

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A Global Suppressor Motif for p53 Cancer Mutants

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (14), p.4930-4935

2004

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A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors

Investigational new drugs, 2014-08, Vol.32 (4), p.653-660

2014

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hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin

Cancer biology & therapy, 2008-01, Vol.7 (1), p.120-128

2008

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A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors

Cancer chemotherapy and pharmacology, 2014-05, Vol.73 (5), p.951-960

2014

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Anti-Neuropilin-1 (MNRP1685A): Unexpected Pharmacokinetic Differences Across Species, from Preclinical Models to Humans

Pharmaceutical research, 2012-09, Vol.29 (9), p.2512-2521

2012

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Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites

Oncogene, 2002-11, Vol.21 (51), p.7901-7911

2002

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Reverse Two-Hybrid and One-Hybrid Systems to Detect Dissociation of Protein-Protein and DNA-Protein Interactions

Proceedings of the National Academy of Sciences - PNAS, 1996-09, Vol.93 (19), p.10315-10320

1996

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p53 Mutants: the Achilles' Heel of Human Cancers?

Cell cycle (Georgetown, Tex.), 2004-08, Vol.3 (8), p.1028-1032

Brachmann, Rainer K.

2004

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Heterogeneous Biomedical Database Integration using a Hybrid Strategy: A P53 Cancer Research Database

Cancer informatics, 2006-01, Vol.2, p.277-287

2006

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ATP, Cancer and p53

Cancer biology & therapy, 2004-07, Vol.3 (7), p.638-640

2004

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hADA3 is required for p53 activity

The EMBO journal, 2001-11, Vol.20 (22), p.6404-6413

2001

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Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins

Nucleic acids research, 2008-01, Vol.36 (1), p.e8-e8

2008

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Dominant-Negative p53 Mutations Selected in Yeast Hit Cancer Hot Spots

Proceedings of the National Academy of Sciences - PNAS, 1996-04, Vol.93 (9), p.4091-4095

1996

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Overexpression of the oncoprotein prothymosin α triggers a p53 response that involves p53 acetylation

Cancer research (Chicago, Ill.), 2006-03, Vol.66 (6), p.3137-3144

2006

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Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants

IEEE/ACM transactions on computational biology and bioinformatics, 2006-04, Vol.3 (2), p.114-125

2006

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Phase 1b study of Wnt inhibitor ipafricept (IPA) with nab-paclitaxel (Nab-P) and gemcitabine (G) in patients with previously untreated stage IV pancreatic cancer (mPDAC)

Clinical cancer research, 2020-07, Vol.26 (20), p.5348-5357

2020

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Tag games in yeast: the two-hybrid system and beyond

Current opinion in biotechnology, 1997-10, Vol.8 (5), p.561-568

1997

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Species-specific endogenous retroviruses shape the transcriptional network of the human tumor suppressor protein p53

Inactive full-length p53 mutants lacking dominant wild-type p53 inhibition highlight loss of heterozygosity as an important aspect of p53 status in human cancers

A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors

Phase Ib clinical trial of the anti-frizzled antibody vantictumab (OMP-18R5) plus paclitaxel in patients with locally advanced or metastatic HER2-negative breast cancer

Phase Ib Study of Wnt Inhibitor Ipafricept with Gemcitabine and nab-paclitaxel in Patients with Previously Untreated Stage IV Pancreatic Cancer

p53 transactivation is involved in the antiproliferative activity of the putative tumor suppressor RBM5

Choosing where to look next in a mutation sequence space: Active Learning of informative p53 cancer rescue mutants

Phosphoinositide 3-Kinase (PI3K) Pathway Alterations Are Associated with Histologic Subtypes and Are Predictive of Sensitivity to PI3K Inhibitors in Lung Cancer Preclinical Models

A Global Suppressor Motif for p53 Cancer Mutants

A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors

hADA2a and hADA3 are required for acetylation, transcriptional activity and proliferative effects of beta-catenin

A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors

Anti-Neuropilin-1 (MNRP1685A): Unexpected Pharmacokinetic Differences Across Species, from Preclinical Models to Humans

Groups of p53 target genes involved in specific p53 downstream effects cluster into different classes of DNA binding sites

Reverse Two-Hybrid and One-Hybrid Systems to Detect Dissociation of Protein-Protein and DNA-Protein Interactions

p53 Mutants: the Achilles' Heel of Human Cancers?

Heterogeneous Biomedical Database Integration using a Hybrid Strategy: A P53 Cancer Research Database

ATP, Cancer and p53

hADA3 is required for p53 activity

Genome wide screens in yeast to identify potential binding sites and target genes of DNA-binding proteins

Dominant-Negative p53 Mutations Selected in Yeast Hit Cancer Hot Spots

Overexpression of the oncoprotein prothymosin α triggers a p53 response that involves p53 acetylation

Functional census of mutation sequence spaces: the example of p53 cancer rescue mutants

Phase 1b study of Wnt inhibitor ipafricept (IPA) with nab-paclitaxel (Nab-P) and gemcitabine (G) in patients with previously untreated stage IV pancreatic cancer (mPDAC)

Tag games in yeast: the two-hybrid system and beyond

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