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Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

Nature structural & molecular biology, 2008-01, Vol.15 (1), p.109-111

2008

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SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition

Nature communications, 2021-10, Vol.12 (1), p.5779-5779, Article 5779

2021

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Defects of mutant DNMT1 are linked to a spectrum of neurological disorders

Brain (London, England : 1878), 2015-04, Vol.138 (Pt 4), p.845-861

2015

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Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation

Nature (London), 2021-08, Vol.596 (7872), p.438-443

2021

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PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation

Cell reports (Cambridge), 2016-10, Vol.17 (4), p.1158-1170

2016

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Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1

Structure (London), 2015-02, Vol.23 (2), p.312-321

2015

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Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18

Molecular cell, 2017-05, Vol.66 (4), p.473-487.e9

2017

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Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Cell, 2006-12, Vol.127 (7), p.1361-1373

2006

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Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss

Nature genetics, 2011-06, Vol.43 (6), p.595-600

2011

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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

Nature communications, 2023-09, Vol.14 (1), p.6091-11, Article 6091

2023

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Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes

Nature communications, 2024-03, Vol.15 (1), p.2064-2064, Article 2064

2024

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Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106

Nature (London), 2012-02, Vol.483 (7387), p.104-107

2012

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Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (36), p.14381-14386

2012

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Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

The Journal of biological chemistry, 2010-02, Vol.285 (6), p.4224-4231

2010

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Heme-Based Sensing by the Mammalian Circadian Protein CLOCK

Inorganic chemistry, 2010-07, Vol.49 (14), p.6349-6365

2010

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ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication

Science advances, 2021-06, Vol.7 (25)

2021

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Stabilization of Nucleosomes by Histone Tails and by FACT Revealed by spFRET Microscopy

Cancers, 2017-01, Vol.9 (1), p.3-3

2017

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Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons

Neurology, 2014-03, Vol.82 (10), p.873-878

2014

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Modification and recognition of chromatin by DNA damage response proteins

Biophysical journal, 2024-02, Vol.123 (3), p.312a-312a

2024

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Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.105775-105775, Article 105775

2024

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Structural Basis of BACH1 Phosphopeptide Recognition by BRCA1 Tandem BRCT Domains

Structure (London), 2004-07, Vol.12 (7), p.1137-1146

2004

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Characterization of binding‐induced changes in dynamics suggests a model for sequence‐nonspecific binding of ssDNA by replication protein A

Protein science, 2002-10, Vol.11 (10), p.2316-2325

2002

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Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

Journal of molecular biology, 2008-08, Vol.381 (2), p.361-372

2008

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A New BRCT Binding Mode in TopBP1-BLM Helicase Interaction

Structure (London), 2017-10, Vol.25 (10), p.1471-1472

2017

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Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin

Journal of molecular biology, 2018-07, Vol.430 (14), p.2042-2050

2018

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Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition

Defects of mutant DNMT1 are linked to a spectrum of neurological disorders

Mechanisms of BRCA1-BARD1 nucleosome recognition and ubiquitylation

PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation

Structural Plasticity of Methyllysine Recognition by the Tandem Tudor Domain of 53BP1

Mechanisms of Ubiquitin-Nucleosome Recognition and Regulation of 53BP1 Chromatin Recruitment by RNF168/169 and RAD18

Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair

Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss

An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

Dimerization-dependent serine protease activity of FAM111A prevents replication fork stalling at topoisomerase 1 cleavage complexes

Structural basis for recognition of H3K56-acetylated histone H3-H4 by the chaperone Rtt106

Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1

Celastrol Inhibits Hsp90 Chaperoning of Steroid Receptors by Inducing Fibrillization of the Co-chaperone p23

Heme-Based Sensing by the Mammalian Circadian Protein CLOCK

ATM-phosphorylated SPOP contributes to 53BP1 exclusion from chromatin during DNA replication

Stabilization of Nucleosomes by Histone Tails and by FACT Revealed by spFRET Microscopy

Ubiquitin ligase defect by DCAF8 mutation causes HMSN2 with giant axons

Modification and recognition of chromatin by DNA damage response proteins

Identification of a conserved α-helical domain at the N terminus of human DNA methyltransferase 1

Structural Basis of BACH1 Phosphopeptide Recognition by BRCA1 Tandem BRCT Domains

Characterization of binding‐induced changes in dynamics suggests a model for sequence‐nonspecific binding of ssDNA by replication protein A

Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites

A New BRCT Binding Mode in TopBP1-BLM Helicase Interaction

Structural Basis for the Interaction of Mutasome Assembly Factor REV1 with Ubiquitin

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