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Death by a thousand cuts: granzyme pathways of programmed cell death

Annual review of immunology, 2008-01, Vol.26 (1), p.389-420

2008

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Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

Nature communications, 2020-03, Vol.11 (1), p.1459-13, Article 1459

2020

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Charity begins at home: non-coding RNA functions in DNA repair

Nature reviews. Molecular cell biology, 2013-03, Vol.14 (3), p.181

2013

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DNA breaks and chromosome pulverization from errors in mitosis

Nature (London), 2012-02, Vol.482 (7383), p.53-58

2012

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Targeting replication stress in cancer therapy

Nature reviews. Drug discovery, 2023-01, Vol.22 (1), p.38-58

2023

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TRIP13 regulates DNA repair pathway choice through REV7 conformational change

Nature cell biology, 2020-01, Vol.22 (1), p.87

2020

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A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer

Nature communications, 2021-09, Vol.12 (1), p.5574-5574, Article 5574

2021

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DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells

Nature (London), 2018-11, Vol.563 (7732), p.522-526

2018

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miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

Molecular cell, 2009-09, Vol.35 (5), p.610-625

2009

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miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

Molecular cell, 2011-01, Vol.41 (2), p.210-220

2011

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A systemic approach to screening high-throughput RT-qPCR data for a suitable set of reference circulating miRNAs

BMC genomics, 2020-01, Vol.21 (1), p.111-111, Article 111

2020

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miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells

Nature structural & molecular biology, 2009-05, Vol.16 (5), p.492-498

2009

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Potential of serum microRNAs as biomarkers of radiation injury and tools for individualization of radiotherapy

Translational research : the journal of laboratory and clinical medicine, 2018-11, Vol.201, p.71-83

2018

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Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks

Molecular cell, 2014-05, Vol.54 (3), p.512-525

2014

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Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (42), p.17041-17046

2013

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Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery

The Journal of cell biology, 2014-08, Vol.206 (4), p.493-507

2014

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Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas

Cell reports (Cambridge), 2018-04, Vol.23 (1), p.100-111

2018

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Dual HDAC and PI3K Inhibition Abrogates NFκB- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (14), p.4007-4021

2018

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MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability

eLife, 2014-04, Vol.3, p.e02445

2014

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Abstract IA-010: Deciphering DNA end resection at DSBs

Clinical cancer research, 2021-04, Vol.27 (8_Supplement), p.IA-010-IA-010

Chowdhury, Dipanjan

2021

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Serum microRNAs are early indicators of survival after radiation-induced hematopoietic injury

Science translational medicine, 2015-05, Vol.7 (287), p.287ra69

2015

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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

Genome Biology, 2018-03, Vol.19 (1), p.37-18, Article 37

2018

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Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles

Nature communications, 2023-06, Vol.14 (1), p.3350-3350, Article 3350

2023

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An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

Nature communications, 2023-09, Vol.14 (1), p.6091-6091, Article 6091

2023

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A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination

Nature structural & molecular biology, 2010-03, Vol.17 (3), p.365

2010

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Death by a thousand cuts: granzyme pathways of programmed cell death

Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer

Charity begins at home: non-coding RNA functions in DNA repair

DNA breaks and chromosome pulverization from errors in mitosis

Targeting replication stress in cancer therapy

TRIP13 regulates DNA repair pathway choice through REV7 conformational change

A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer

DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

miR-182-Mediated Downregulation of BRCA1 Impacts DNA Repair and Sensitivity to PARP Inhibitors

A systemic approach to screening high-throughput RT-qPCR data for a suitable set of reference circulating miRNAs

miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells

Potential of serum microRNAs as biomarkers of radiation injury and tools for individualization of radiotherapy

Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks

Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance

Phosphorylated RPA recruits PALB2 to stalled DNA replication forks to facilitate fork recovery

Multifaceted Impact of MicroRNA 493-5p on Genome-Stabilizing Pathways Induces Platinum and PARP Inhibitor Resistance in BRCA2-Mutated Carcinomas

Dual HDAC and PI3K Inhibition Abrogates NFκB- and FOXM1-Mediated DNA Damage Response to Radiosensitize Pediatric High-Grade Gliomas

MicroRNAs down-regulate homologous recombination in the G1 phase of cycling cells to maintain genomic stability

Abstract IA-010: Deciphering DNA end resection at DSBs

Serum microRNAs are early indicators of survival after radiation-induced hematopoietic injury

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles

An autoinhibited state of 53BP1 revealed by small molecule antagonists and protein engineering

A PP4 phosphatase complex dephosphorylates RPA2 to facilitate DNA repair via homologous recombination

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