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Hyperthermia Intensifies α-Mangostin and Synthetic Xanthones' Antimalignancy Properties

International journal of molecular sciences, 2024-08, Vol.25 (16), p.8874

2024

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Metabolic stability and its role in the discovery of new chemical entities

Acta pharmaceutica (Zagreb, Croatia), 2019-09, Vol.69 (3), p.345-361

2019

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Electrochemical simulation of metabolism for antitumor-active imidazoacridinone C-1311 and in silico prediction of drug metabolic reactions

Journal of pharmaceutical and biomedical analysis, 2019-05, Vol.169, p.269-278

2019

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In silico and in vitro evaluation of a safety profile of a cosmetic ingredient: 4-methoxychalcone (4-MC)

Toxicology in vitro, 2023-12, Vol.93, p.105696-105696, Article 105696

2023

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The Involvement of Xanthone and ( E )-Cinnamoyl Chromophores for the Design and Synthesis of Novel Sunscreening Agents

International journal of molecular sciences, 2020-12, Vol.22 (1), p.34

2020

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In vitro safety evaluation of (6-methoxy-9-oxo-9 H -xanthen-2-yl)methyl ( E )-3-(2,4-dimethoxyphenyl)acrylate (K-116) - the novel potential UV filter designed by means of a double chromophore strategy

Xenobiotica, 2024-07, Vol.54 (6), p.1-278

2024

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S (+)-(2 E )- N -(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4372

2020

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Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C-1305

Journal of pharmaceutical analysis, 2020-08, Vol.10 (4), p.376-384

2020

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Influence of New Synthetic Xanthones on the Proliferation and Migration Potential of Cancer Cell Lines In Vitro

Anti-cancer agents in medicinal chemistry, 2019-01, Vol.19 (16), p.1949-1965

2019

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Novel Xanthone Derivatives Impair Growth and Invasiveness of Colon Cancer Cells In Vitro

Biomolecules (Basel, Switzerland), 2021-10, Vol.11 (10), p.1480

2021

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Discovery of Novel UV-Filters with Favorable Safety Profiles in the 5-Arylideneimidazolidine-2,4-dione Derivatives Group

Molecules (Basel, Switzerland), 2019-06, Vol.24 (12), p.2321

2019

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HBK-10, A Compound with α1-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats

Pharmaceuticals (Basel, Switzerland), 2022-10, Vol.15 (10), p.1256

2022

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Microbial biotransformation of some novel hydantoin derivatives: Perspectives for bioremediation of potential sunscreen agents

Chemosphere (Oxford), 2019-11, Vol.234, p.108-115

2019

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Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Bioorganic & medicinal chemistry letters, 2019-11, Vol.29 (21), p.126679, Article 126679

2019

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Antibacterial and antibiofilm agents in the group of xanthone derivatives with piperazine moiety active against drug-resistant Helicobacter pylori strains

Bioorganic chemistry, 2024-12, Vol.153, p.107755, Article 107755

2024

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Discovery of (E)-3-(4-chlorophenyl)-N-(5-hydroxypentyl)acrylamide among N-substituted cinnamamide derivatives as a novel cosmetic ingredient for hyperpigmentation

Bioorganic chemistry, 2024-09, Vol.150, p.107533, Article 107533

2024

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Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (2), p.471-482

2017

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Cardiovascular activity of the chiral xanthone derivatives

Bioorganic & medicinal chemistry, 2015-10, Vol.23 (20), p.6714-6724

2015

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Anticonvulsant and analgesic in neuropathic pain activity in a group of new aminoalkanol derivatives

Bioorganic & medicinal chemistry letters, 2020-08, Vol.30 (16), p.127325, Article 127325

2020

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Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT1A and D2 Receptors

Pharmaceuticals (Basel, Switzerland), 2021-07, Vol.14 (8), p.744

2021

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Preliminary antifungal activity assay of selected chlorine‐containing derivatives of xanthone and phenoxyethyl amines

Chemical biology & drug design, 2018-11, Vol.92 (5), p.1867-1875

2018

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Cunninghamella Biotransformation--Similarities to Human Drug Metabolism and Its Relevance for the Drug Discovery Process

Current drug metabolism, 2016-02, Vol.17 (2), p.107-117

2016

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Surprising and unusual ingredients of modern cosmetics

Farmacja Polska, 2021-06, Vol.77 (5), p.287-296

2021

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Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols

European journal of medicinal chemistry, 2016-01, Vol.107, p.26-37

2016

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Synthesis and anticonvulsant activity of phenoxyacetyl derivatives of amines, including aminoalkanols and amino acids

MedChemComm, 2018-11, Vol.9 (11), p.1933-1948

2018

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Hyperthermia Intensifies α-Mangostin and Synthetic Xanthones' Antimalignancy Properties

Metabolic stability and its role in the discovery of new chemical entities

Electrochemical simulation of metabolism for antitumor-active imidazoacridinone C-1311 and in silico prediction of drug metabolic reactions

In silico and in vitro evaluation of a safety profile of a cosmetic ingredient: 4-methoxychalcone (4-MC)

The Involvement of Xanthone and ( E )-Cinnamoyl Chromophores for the Design and Synthesis of Novel Sunscreening Agents

In vitro safety evaluation of (6-methoxy-9-oxo-9 H -xanthen-2-yl)methyl ( E )-3-(2,4-dimethoxyphenyl)acrylate (K-116) - the novel potential UV filter designed by means of a double chromophore strategy

S (+)-(2 E )- N -(2-Hydroxypropyl)-3-Phenylprop-2-Enamide (KM-568): A Novel Cinnamamide Derivative with Anticonvulsant Activity in Animal Models of Seizures and Epilepsy

Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C-1305

Influence of New Synthetic Xanthones on the Proliferation and Migration Potential of Cancer Cell Lines In Vitro

Novel Xanthone Derivatives Impair Growth and Invasiveness of Colon Cancer Cells In Vitro

Discovery of Novel UV-Filters with Favorable Safety Profiles in the 5-Arylideneimidazolidine-2,4-dione Derivatives Group

HBK-10, A Compound with α1-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats

Microbial biotransformation of some novel hydantoin derivatives: Perspectives for bioremediation of potential sunscreen agents

Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Antibacterial and antibiofilm agents in the group of xanthone derivatives with piperazine moiety active against drug-resistant Helicobacter pylori strains

Discovery of (E)-3-(4-chlorophenyl)-N-(5-hydroxypentyl)acrylamide among N-substituted cinnamamide derivatives as a novel cosmetic ingredient for hyperpigmentation

Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH3 or 2-CH3

Cardiovascular activity of the chiral xanthone derivatives

Anticonvulsant and analgesic in neuropathic pain activity in a group of new aminoalkanol derivatives

Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT1A and D2 Receptors

Preliminary antifungal activity assay of selected chlorine‐containing derivatives of xanthone and phenoxyethyl amines

Cunninghamella Biotransformation--Similarities to Human Drug Metabolism and Its Relevance for the Drug Discovery Process

Surprising and unusual ingredients of modern cosmetics

Anticonvulsant activity, crystal structures, and preliminary safety evaluation of N-trans-cinnamoyl derivatives of selected (un)modified aminoalkanols

Synthesis and anticonvulsant activity of phenoxyacetyl derivatives of amines, including aminoalkanols and amino acids

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