UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

Microbiology spectrum, 2022-04, Vol.10 (2), p.e0216721

2022

Volltextzugriff (PDF)

Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

Respiratory research, 2011-04, Vol.12 (53), p.54-54, Article 54

2011

Volltextzugriff (PDF)

Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation

Drug metabolism and disposition, 2014-09, Vol.42 (9), p.1367-1378

2014

Volltextzugriff (PDF)

Individualized treatment strategies for hyperuricemia informed by a semi‐mechanistic exposure‐response model of uric acid dynamics

Physiological reports, 2018-03, Vol.6 (5), p.e13614-n/a

2018

Volltextzugriff (PDF)

Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers

Anesthesiology (Philadelphia), 2002-10, Vol.97 (4), p.827-836

2002

Volltextzugriff (PDF)

Pharmacodynamics of orally administered sustained-release hydromorphone in humans

Anesthesiology (Philadelphia), 2001, Vol.94 (1), p.63-73

2001

Volltextzugriff (PDF)

Pharmacokinetic/Pharmacodynamic Modeling in Drug Research and Development

Journal of clinical pharmacology, 2000-12, Vol.40 (12), p.1399-1418

2000

Volltextzugriff (PDF)

Fostering Culture and Optimizing Organizational Structure for Implementing Model-Based Drug Development

Journal of clinical pharmacology, 2010-09, Vol.50 (S9), p.146S-150S

2010

Volltextzugriff (PDF)

Innovative approaches to clinical development and trial design

Annali dell'Istituto superiore di sanità, 2011, Vol.47 (1), p.8-13

2011

Volltextzugriff (PDF)

Communicating With the FDA: The "Third Rail" of a New Model for Drug Development

Journal of clinical pharmacology, 2008-02, Vol.48 (2), p.144-145

2008

Volltextzugriff (PDF)

Lumbar Epidural morphine in humans and supraspinal analgesia to experimental heat pain

Anesthesiology (Philadelphia), 2000-02, Vol.92 (2), p.312-324

2000

Volltextzugriff (PDF)

A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect

Clinical pharmacology and therapeutics, 1997-01, Vol.61 (1), p.45-58

1997

Volltextzugriff (PDF)

The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers

Anesthesiology (Philadelphia), 1993-11, Vol.79 (5), p.881-892

1993

Volltextzugriff (PDF)

Computer simulation of the effects of alterations in blood flows and body composition on thiopental pharmacokinetics in humans

Anesthesiology (Philadelphia), 1997-10, Vol.87 (4), p.884-899

1997

Volltextzugriff (PDF)

Application of physiologic models to predict the influence of changes in body composition and blood flows on the pharmacokinetics of fentanyl and alfentanil in patients

Anesthesiology (Philadelphia), 1998-03, Vol.88 (3), p.657-667

1998

Volltextzugriff (PDF)

Enriched analgesic efficacy studies: An assessment by clinical trial simulation

Contemporary clinical trials, 2006-04, Vol.27 (2), p.165-173

2006

Volltextzugriff (PDF)

Characterization and validation of a pharmacokinetic model for controlled‐release oxycodone

British journal of clinical pharmacology, 1996-12, Vol.42 (6), p.747-756

1996

Volltextzugriff (PDF)

Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet

European journal of pharmaceutical sciences, 2017-11, Vol.109, p.S39-S46

2017

Volltextzugriff (PDF)

Exposure‐Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction

Journal of clinical pharmacology, 2017-05, Vol.57 (5), p.573-583

2017

Volltextzugriff (PDF)

The future of drug development: advancing clinical trial design

Nature reviews. Drug discovery, 2009-12, Vol.8 (12), p.949-957

2009

Volltextzugriff (PDF)

Inadequate anaesthesia in lethal injection for execution

The Lancet (British edition), 2005-09, Vol.366 (9491), p.1073-1073

Groner, Jonathan I

2005

Volltextzugriff (PDF)

Electroencephalographic effects of benzodiazepines. II. Pharmacodynamic modeling of the electroencephalographic effects of midazolam and diazepam

Clinical pharmacology and therapeutics, 1990-11, Vol.48 (5), p.555-567

1990

Volltextzugriff (PDF)

Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugs

Journal of pharmacokinetics and pharmacodynamics, 2010-12, Vol.37 (6), p.629-644

2010

Volltextzugriff (PDF)

Pharmacokinetic-pharmacodynamic modeling in drug development: Application to the investigational opioid trefentanil

Clinical pharmacology and therapeutics, 1994-09, Vol.56 (3), p.261-271

1994

Volltextzugriff (PDF)

Integrating dose estimation into a decision‐making framework for model‐based drug development

Pharmaceutical statistics : the journal of the pharmaceutical industry, 2018-03, Vol.17 (2), p.155-168

2018

Volltextzugriff (PDF)

1 – 25 von 80

Suche als RSS-Feed

Aktive Filter

ThemaHumans

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(79)
Mit Volltextzugriff
(51)

Publikationsform

Artikel
(80)

Sprache

Englisch
(80)

Erscheinungsjahr

n.n

Thema

Life Sciences & Biomedicine
(72)
Science & Technology
(72)
Adult
(42)
Male
(37)
Pharmacology & Pharmacy
(36)
Biological And Medical Sciences
(35)
Medical Sciences
(35)
Pharmacology. Drug Treatments
(33)
Anesthesiology
(27)
Neuropharmacology
(25)
Middle Aged
(24)
Kinetics
(20)
Models, Biological
(20)
Female
(19)
Animals
(17)
Anesthetics. Neuromuscular Blocking Agents
(14)
Aged
(11)
Pharmacokinetics
(10)
Time Factors
(10)

14 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19

Characterization of the bronchodilatory dose response to indacaterol in patients with chronic obstructive pulmonary disease using model-based approaches

Translational pharmacokinetic modeling of fingolimod (FTY720) as a paradigm compound subject to sphingosine kinase-mediated phosphorylation

Individualized treatment strategies for hyperuricemia informed by a semi‐mechanistic exposure‐response model of uric acid dynamics

Input characteristics and bioavailability after administration of immediate and a new extended-release formulation of hydromorphone in healthy volunteers

Pharmacodynamics of orally administered sustained-release hydromorphone in humans

Pharmacokinetic/Pharmacodynamic Modeling in Drug Research and Development

Fostering Culture and Optimizing Organizational Structure for Implementing Model-Based Drug Development

Innovative approaches to clinical development and trial design

Communicating With the FDA: The "Third Rail" of a New Model for Drug Development

Lumbar Epidural morphine in humans and supraspinal analgesia to experimental heat pain

A comparison of spectral edge, delta power, and bispectral index as EEG measures of alfentanil, propofol, and midazolam drug effect

The pharmacokinetics of the new short-acting opioid remifentanil (GI87084B) in healthy adult male volunteers

Computer simulation of the effects of alterations in blood flows and body composition on thiopental pharmacokinetics in humans

Application of physiologic models to predict the influence of changes in body composition and blood flows on the pharmacokinetics of fentanyl and alfentanil in patients

Enriched analgesic efficacy studies: An assessment by clinical trial simulation

Characterization and validation of a pharmacokinetic model for controlled‐release oxycodone

Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet

Exposure‐Response Analyses Supporting Ticagrelor Dosing Recommendation in Patients With Prior Myocardial Infarction

The future of drug development: advancing clinical trial design

Inadequate anaesthesia in lethal injection for execution

Electroencephalographic effects of benzodiazepines. II. Pharmacodynamic modeling of the electroencephalographic effects of midazolam and diazepam

Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugs

Pharmacokinetic-pharmacodynamic modeling in drug development: Application to the investigational opioid trefentanil

Integrating dose estimation into a decision‐making framework for model‐based drug development

Aktive Filter

Suchergebnisse filtern