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In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells

Nature communications, 2020-10, Vol.11 (1), p.5060-14, Article 5060

2020

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Retinoblastoma: From genes to patient care

European journal of medical genetics, 2023-01, Vol.66 (1), p.104674-104674, Article 104674

2023

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Translational Pharmacokinetic‐Pharmacodynamic Modeling and Simulation: Optimizing 5‐Fluorouracil Dosing in Children With Pediatric Ependymoma

CPT: pharmacometrics and systems pharmacology, 2016-04, Vol.5 (4), p.211-221

2016

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Cell migration in paediatric glioma; characterisation and potential therapeutic targeting

British journal of cancer, 2015-02, Vol.112 (4), p.693-703

2015

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Combined Microdialysis-Tumor Homogenate Method for the Study of the Steady State Compartmental Distribution of a Hydrophobic Anticancer Drug in Patient-Derived Xenografts

Pharmaceutical research, 2015-09, Vol.32 (9), p.2889-2900

2015

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Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

PloS one, 2017-01, Vol.12 (1), p.e0169485

2017

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PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma

Nature communications, 2019-08, Vol.10 (1), p.3790-10, Article 3790

2019

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H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models

The Journal of clinical investigation, 2022-11, Vol.132 (22), p.1-20

2022

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Selective Accumulation of Galactomannan Amphiphilic Nanomaterials in Pediatric Solid Tumor Xenografts Correlates with GLUT1 Gene Expression

ACS applied materials & interfaces, 2019-10, Vol.11 (42), p.38483-38496

2019

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EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Nature medicine, 2017-04, Vol.23 (4), p.483-492

2017

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Nanomedicines in the future of pediatric therapy

Advanced drug delivery reviews, 2014-06, Vol.73, p.140-161

2014

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Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

Nature genetics, 2014-05, Vol.46 (5), p.457-461

2014

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PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo

Scientific reports, 2024-01, Vol.14 (1), p.328-328, Article 328

2024

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Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination

The Journal of experimental medicine, 2017-01, Vol.214 (1), p.245-267

2017

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New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery

Advanced drug delivery reviews, 2010-03, Vol.62 (4), p.547-559

2010

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Drug delivery systems in HIV pharmacotherapy: What has been done and the challenges standing ahead

Journal of controlled release, 2009-08, Vol.138 (1), p.2-15

2009

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Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

Science translational medicine, 2019-01, Vol.11 (476)

2019

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Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells

PloS one, 2016-07, Vol.11 (7), p.e0160094-e0160094

2016

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Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

The Journal of experimental medicine, 2018-01, Vol.215 (1), p.141-157

2018

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RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis

Science advances, 2020-10, Vol.6 (43)

2020

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Role of ATP-Binding Cassette and Solute Carrier Transporters in Erlotinib CNS Penetration and Intracellular Accumulation

Clinical cancer research, 2011-01, Vol.17 (1), p.89-99

2011

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In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells

Retinoblastoma: From genes to patient care

Translational Pharmacokinetic‐Pharmacodynamic Modeling and Simulation: Optimizing 5‐Fluorouracil Dosing in Children With Pediatric Ependymoma

Cell migration in paediatric glioma; characterisation and potential therapeutic targeting

Combined Microdialysis-Tumor Homogenate Method for the Study of the Steady State Compartmental Distribution of a Hydrophobic Anticancer Drug in Patient-Derived Xenografts

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma

H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models

Selective Accumulation of Galactomannan Amphiphilic Nanomaterials in Pediatric Solid Tumor Xenografts Correlates with GLUT1 Gene Expression

EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas

Nanomedicines in the future of pediatric therapy

Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma

PRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo

Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination

New old challenges in tuberculosis: Potentially effective nanotechnologies in drug delivery

Drug delivery systems in HIV pharmacotherapy: What has been done and the challenges standing ahead

Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries

Therapeutic targeting of the RB1 pathway in retinoblastoma with the oncolytic adenovirus VCN-01

Schedule-Dependent Antiangiogenic and Cytotoxic Effects of Chemotherapy on Vascular Endothelial and Retinoblastoma Cells

Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

Repurposing Vandetanib plus Everolimus for the Treatment of ACVR1 -Mutant Diffuse Intrinsic Pontine Glioma

RING1B recruits EWSR1-FLI1 and cooperates in the remodeling of chromatin necessary for Ewing sarcoma tumorigenesis

Selective inhibition of HDAC6 regulates expression of the oncogenic driver EWSR1-FLI1 through the EWSR1 promoter in Ewing sarcoma

Role of ATP-Binding Cassette and Solute Carrier Transporters in Erlotinib CNS Penetration and Intracellular Accumulation

Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma

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