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Chemistry and Biology Of Multicomponent Reactions

Chemical reviews, 2012-06, Vol.112 (6), p.3083-3135

2012

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GPCR Dynamics: Structures in Motion

Chemical reviews, 2017-01, Vol.117 (1), p.139-155

2017

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G‐Protein‐Coupled Receptor–Membrane Interactions Depend on the Receptor Activation State

Journal of computational chemistry, 2020-02, Vol.41 (5), p.460-471

2020

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Conducting Nanomaterial Sensor Using Natural Receptors

Chemical reviews, 2019-01, Vol.119 (1), p.36-93

2019

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Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors

Chemical reviews, 2016-06, Vol.116 (11), p.6707-6741

2016

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Discovery of new GPCR ligands to illuminate new biology

Nature chemical biology, 2017-11, Vol.13 (11), p.1143-1151

2017

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Allostery and Biased Agonism at Class B G Protein-Coupled Receptors

Chemical reviews, 2017-01, Vol.117 (1), p.111-138

2017

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The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)

Angewandte Chemie (International ed. in English), 2013-06, Vol.52 (25), p.6380-6388

Kobilka, Brian

International ed. in English, 2013

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Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor

Journal of the American Chemical Society, 2019-07, Vol.141 (29), p.11522-11530

2019

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The role of the lipid environment in the activity of G protein coupled receptors

Biophysical chemistry, 2022-06, Vol.285 (21), p.106794-106794, Article 106794

2022

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Binding Hotspot and Activation Mechanism of Maltitol and Lactitol toward the Human Sweet Taste Receptor

Journal of agricultural and food chemistry, 2020-07, Vol.68 (30), p.7974-7983

2020

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Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands

International journal of molecular sciences, 2023-03, Vol.24 (7), p.6187

Shpakov, Alexander O

2023

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Umami-enhancing effect of typical kokumi-active γ-glutamyl peptides evaluated via sensory analysis and molecular modeling approaches

Food chemistry, 2021-02, Vol.338, p.128018, Article 128018

2021

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The Effects of Sodium Ions on Ligand Binding and Conformational States of G Protein-Coupled ReceptorsInsights from Mass Spectrometry

Journal of the American Chemical Society, 2021-03, Vol.143 (11), p.4085-4089

2021

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Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization

Journal of chemical information and modeling, 2013-12, Vol.53 (12), p.3399-3409

2013

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Allosteric Modulation of GPCRs of Class A by Cholesterol

International journal of molecular sciences, 2021-02, Vol.22 (4), p.1953

2021

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Structure-Function Analyses of Human Bitter Taste Receptors-Where Do We Stand?

Molecules (Basel, Switzerland), 2020-09, Vol.25 (19), p.4423

2020

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The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components

International journal of molecular sciences, 2014-05, Vol.15 (5), p.8570-8590

2014

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Structural Determinants of the Supramolecular Organization of G Protein-Coupled Receptors in Bilayers

Journal of the American Chemical Society, 2012-07, Vol.134 (26), p.10959-10965

2012

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GPCR crystal structures: Medicinal chemistry in the pocket

Bioorganic & medicinal chemistry, 2015-07, Vol.23 (14), p.3880-3906

2015

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Structure and Dynamics of GPCRs in Lipid Membranes: Physical Principles and Experimental Approaches

Molecules (Basel, Switzerland), 2020-10, Vol.25 (20), p.4729

2020

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Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor

PloS one, 2019-03, Vol.14 (3), p.e0213552

2019

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Labeling and Single-Molecule Methods To Monitor G Protein-Coupled Receptor Dynamics

Chemical reviews, 2017-01, Vol.117 (1), p.186-245

2017

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In Silico Investigation of Bitter Hop-Derived Compounds and Their Cognate Bitter Taste Receptors

Journal of agricultural and food chemistry, 2020-09, Vol.68 (38), p.10414-10423

2020

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A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs

Molecules (Basel, Switzerland), 2019-06, Vol.24 (11), p.2097

2019

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Chemistry and Biology Of Multicomponent Reactions

GPCR Dynamics: Structures in Motion

G‐Protein‐Coupled Receptor–Membrane Interactions Depend on the Receptor Activation State

Conducting Nanomaterial Sensor Using Natural Receptors

Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors

Discovery of new GPCR ligands to illuminate new biology

Allostery and Biased Agonism at Class B G Protein-Coupled Receptors

The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)

Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor

The role of the lipid environment in the activity of G protein coupled receptors

Binding Hotspot and Activation Mechanism of Maltitol and Lactitol toward the Human Sweet Taste Receptor

Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands

Umami-enhancing effect of typical kokumi-active γ-glutamyl peptides evaluated via sensory analysis and molecular modeling approaches

The Effects of Sodium Ions on Ligand Binding and Conformational States of G Protein-Coupled ReceptorsInsights from Mass Spectrometry

Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization

Allosteric Modulation of GPCRs of Class A by Cholesterol

Structure-Function Analyses of Human Bitter Taste Receptors-Where Do We Stand?

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components

Structural Determinants of the Supramolecular Organization of G Protein-Coupled Receptors in Bilayers

GPCR crystal structures: Medicinal chemistry in the pocket

Structure and Dynamics of GPCRs in Lipid Membranes: Physical Principles and Experimental Approaches

Structural insights into the differences among lactisole derivatives in inhibitory mechanisms against the human sweet taste receptor

Labeling and Single-Molecule Methods To Monitor G Protein-Coupled Receptor Dynamics

In Silico Investigation of Bitter Hop-Derived Compounds and Their Cognate Bitter Taste Receptors

A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs

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