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Catalytic Ring-Opening of Cyclic Alcohols Enabled by PCET Activation of Strong O–H Bonds

Journal of the American Chemical Society, 2016-08, Vol.138 (34), p.10794-10797

2016

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Enantioselective Photoredox Catalysis Enabled by Proton-Coupled Electron Transfer: Development of an Asymmetric Aza-Pinacol Cyclization

Journal of the American Chemical Society, 2013-11, Vol.135 (47), p.17735-17738

2013

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Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir

Chemical science (Cambridge), 2016-03, Vol.7 (3), p.2066-2073

2016

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Organophotochemical SNAr Reactions of Mildly Electron‐Poor Fluoroarenes

European journal of organic chemistry, 2020-05, Vol.2020 (18), p.2766-2770

2020

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Convergent Syntheses of Isomeric Imidazolospiroketones as Templates for Acetyl-CoA Carboxylase (ACC) Inhibitors

Journal of organic chemistry, 2023-10, Vol.88 (19), p.13727-13740

2023

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PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease

Journal of medicinal chemistry, 2021-01, Vol.64 (1), p.326-342

2021

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Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19

Organic process research & development, 2023-02, Vol.27 (12), p.2223-2239

2023

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A SN1 mechanistic approach to the Williamson ether reaction via photoredox catalysis applied to benzylic C(sp3)–H bonds

Tetrahedron, 2022-10, Vol.125, p.132986, Article 132986

2022

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A photoredox-catalyzed approach for formal hydride abstraction to enable C –H functionalization with nucleophilic partners (F, C, O, N, and Br/Cl)

Chem catalysis, 2022-06, Vol.2 (2), p.292-308

2022

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Organophotochemical S N Ar Reactions of Mildly Electron‐Poor Fluoroarenes

European journal of organic chemistry, 2020-05, Vol.2020 (18), p.2766-2770

2020

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Synthesis of Enantiopure Fluoropiperidines via Biocatalytic Desymmetrization and Flow Photochemical Decarboxylative Fluorination

Organic process research & development, 2024-10, Vol.28 (10), p.3801-3807

2024

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Synthesis of Nirmatrelvir: Development of Magnesium Sulfate-Mediated Aminolysis for the Manufacture of the Eastern Fragment

Organic process research & development, 2023-12, Vol.27 (12), p.2271-2279

2023

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Synthesis of Nirmatrelvir: Development of an Efficient, Scalable Process to Generate the Western Fragment

Organic process research & development, 2023-12, Vol.27 (12), p.2240-2249

2023

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A photoredox-catalyzed approach for formal hydride abstraction to enable Csp3–H functionalization with nucleophilic partners (F, C, O, N, and Br/Cl)

Chem catalysis, 2022-02, Vol.2 (2), p.292-308

2022

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Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvirElectronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. See DOI: 10.1039/c5sc03350k

2016-02

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Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. See DOI: 10.1039/c5sc03350k

Chemical science (Cambridge), 2015-12, Vol.7 (3), p.2066-2073

2015

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ChemInform Abstract: Proton-Coupled Electron Transfer in Organic Synthesis: Novel Homolytic Bond Activations and Catalytic Asymmetric Reactions with Free Radicals

ChemInform, 2015-03, Vol.46 (10), p.no-no

2015

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ChemInform Abstract: Enantioselective Photoredox Catalysis Enabled by Proton-Coupled Electron Transfer: Development of an Asymmetric Aza-Pinacol Cyclization

ChemInform, 2014-06, Vol.45 (23), p.no-no

2014

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Catalytic Ring-Opening of Cyclic Alcohols Enabled by PCET Activation of Strong O–H Bonds

Enantioselective Photoredox Catalysis Enabled by Proton-Coupled Electron Transfer: Development of an Asymmetric Aza-Pinacol Cyclization

Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir

Organophotochemical SNAr Reactions of Mildly Electron‐Poor Fluoroarenes

Convergent Syntheses of Isomeric Imidazolospiroketones as Templates for Acetyl-CoA Carboxylase (ACC) Inhibitors

PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease

Early Clinical Development of Lufotrelvir as a Potential Therapy for COVID-19

A SN1 mechanistic approach to the Williamson ether reaction via photoredox catalysis applied to benzylic C(sp3)–H bonds

A photoredox-catalyzed approach for formal hydride abstraction to enable C –H functionalization with nucleophilic partners (F, C, O, N, and Br/Cl)

Organophotochemical S N Ar Reactions of Mildly Electron‐Poor Fluoroarenes

Synthesis of Enantiopure Fluoropiperidines via Biocatalytic Desymmetrization and Flow Photochemical Decarboxylative Fluorination

Synthesis of Nirmatrelvir: Development of Magnesium Sulfate-Mediated Aminolysis for the Manufacture of the Eastern Fragment

Synthesis of Nirmatrelvir: Development of an Efficient, Scalable Process to Generate the Western Fragment

A photoredox-catalyzed approach for formal hydride abstraction to enable Csp3–H functionalization with nucleophilic partners (F, C, O, N, and Br/Cl)

Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvirElectronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. See DOI: 10.1039/c5sc03350k

Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir† †Electronic supplementary information (ESI) available: Detailed experimental procedures and characterization data for all new compounds. See DOI: 10.1039/c5sc03350k

ChemInform Abstract: Proton-Coupled Electron Transfer in Organic Synthesis: Novel Homolytic Bond Activations and Catalytic Asymmetric Reactions with Free Radicals

ChemInform Abstract: Enantioselective Photoredox Catalysis Enabled by Proton-Coupled Electron Transfer: Development of an Asymmetric Aza-Pinacol Cyclization

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