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Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes

Angewandte Chemie International Edition, 2015-07, Vol.54 (31), p.8896-8927

International ed. in English, 2015

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Modulators of Protein–Protein Interactions

Chemical reviews, 2014-05, Vol.114 (9), p.4695-4748

2014

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Hydrocarbon Stapled Peptides as Modulators of Biological Function

ACS chemical biology, 2015-06, Vol.10 (6), p.1362-1375

2015

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New Modalities for Challenging Targets in Drug Discovery

Angewandte Chemie International Edition, 2017-08, Vol.56 (35), p.10294-10323

International ed. in English, 2017

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The Therapeutic Potential of PTEN Modulation: Targeting Strategies from Gene to Protein

Cell chemical biology, 2018-01, Vol.25 (1), p.19-29

2018

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Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets

Nature communications, 2017-03, Vol.8 (1), p.14690-14690, Article 14690

2017

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Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

Nature communications, 2016-04, Vol.7 (1), p.11300-11300, Article 11300

2016

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Direct Modulation of Small GTPase Activity and Function

Angewandte Chemie International Edition, 2015-11, Vol.54 (46), p.13516-13537

International ed. in English, 2015

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Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (44), p.17942-17947

2012

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Nucleic Acid Templated Reactions: Consequences of Probe Reactivity and Readout Strategy for Amplified Signaling and Sequence Selectivity

Chemistry : a European journal, 2009-07, Vol.15 (27), p.6723-6730

2009

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Direct Targeting of Rab-GTPase-Effector Interactions

Angewandte Chemie International Edition, 2014-02, Vol.53 (9), p.2498-2503

International ed. in English, 2014

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Triplex Molecular Beacons as Modular Probes for DNA Detection

Angewandte Chemie International Edition, 2007-01, Vol.46 (27), p.5223-5225

2007

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A protein tertiary structure mimetic modulator of the Hippo signalling pathway

Nature communications, 2020-10, Vol.11 (1), p.5425-5425, Article 5425

2020

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Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase

ACS chemical biology, 2016-08, Vol.11 (8), p.2375-2382

2016

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Achieving Turnover in DNA-Templated Reactions

Chembiochem : a European journal of chemical biology, 2008-09, Vol.9 (14), p.2185-2192

2008

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Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns

Nature chemistry, 2020-04, Vol.12 (4), p.331-337

2020

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Target-Catalyzed Transfer Reactions for the Amplified Detection of RNA

Angewandte Chemie (International ed.), 2008-09, Vol.47 (37), p.7119-7122

2008

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Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes

Angewandte Chemie International Edition, 2015-11, Vol.54 (46), p.13796-13800

International ed. in English, 2015

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Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

mBio, 2018-09, Vol.9 (5)

2018

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Protein Macrocyclization for Tertiary Structure Stabilization

Chembiochem : a European journal of chemical biology, 2021-09, Vol.22 (17), p.2672-2679

2021

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Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

Nature protocols, 2011-06, Vol.6 (6), p.761-771

2011

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Stapling of Peptides Potentiates the Antibiotic Treatment of Acinetobacter baumannii In Vivo

Antibiotics (Basel), 2022-02, Vol.11 (2), p.273

2022

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Small-molecule modulation of Ras signaling

Nature chemical biology, 2014-08, Vol.10 (8), p.613-622

2014

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Identification of an H-Ras nanocluster disrupting peptide

Communications biology, 2024-07, Vol.7 (1), p.837-15, Article 837

2024

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Synthesis of all-hydrocarbon stapled [alpha]-helical peptides by ring-closing olefin metathesis

Nature protocols, 2011-06, Vol.6 (6), p.761

2011

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Structure-Based Design of Inhibitors of Protein-Protein Interactions: Mimicking Peptide Binding Epitopes

Modulators of Protein–Protein Interactions

Hydrocarbon Stapled Peptides as Modulators of Biological Function

New Modalities for Challenging Targets in Drug Discovery

The Therapeutic Potential of PTEN Modulation: Targeting Strategies from Gene to Protein

Plant cysteine oxidases are dioxygenases that directly enable arginyl transferase-catalysed arginylation of N-end rule targets

Orthogonal ring-closing alkyne and olefin metathesis for the synthesis of small GTPase-targeting bicyclic peptides

Direct Modulation of Small GTPase Activity and Function

Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin

Nucleic Acid Templated Reactions: Consequences of Probe Reactivity and Readout Strategy for Amplified Signaling and Sequence Selectivity

Direct Targeting of Rab-GTPase-Effector Interactions

Triplex Molecular Beacons as Modular Probes for DNA Detection

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

Protease-Resistant and Cell-Permeable Double-Stapled Peptides Targeting the Rab8a GTPase

Achieving Turnover in DNA-Templated Reactions

Proteomimetics as protein-inspired scaffolds with defined tertiary folding patterns

Target-Catalyzed Transfer Reactions for the Amplified Detection of RNA

Redox Modulation of PTEN Phosphatase Activity by Hydrogen Peroxide and Bisperoxidovanadium Complexes

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB

Protein Macrocyclization for Tertiary Structure Stabilization

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis

Stapling of Peptides Potentiates the Antibiotic Treatment of Acinetobacter baumannii In Vivo

Small-molecule modulation of Ras signaling

Identification of an H-Ras nanocluster disrupting peptide

Synthesis of all-hydrocarbon stapled [alpha]-helical peptides by ring-closing olefin metathesis

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