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TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data

Human mutation, 2016-09, Vol.37 (9), p.865-876

2016

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Discoveries and controversies in BCL‐2 protein‐mediated apoptosis

The FEBS journal, 2016-07, Vol.283 (14), p.2690-2700

2016

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Tumor suppressive role for kinases phosphorylating p53 in DNA damage‐induced apoptosis

Cancer science, 2018-11, Vol.109 (11), p.3376-3382

2018

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iSEE: Interface structure, evolution, and energy‐based machine learning predictor of binding affinity changes upon mutations

Proteins, structure, function, and bioinformatics, 2019-02, Vol.87 (2), p.110-119

2019

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EZH2 cooperates with gain‐of‐function p53 mutants to promote cancer growth and metastasis

The EMBO journal, 2019-03, Vol.38 (5), p.n/a

2019

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Regulation of cellular senescence via the FOXO4‐p53 axis

FEBS letters, 2018-06, Vol.592 (12), p.2083-2097

2018

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Tetramer formation of tumor suppressor protein p53: Structure, function, and applications

Biopolymers, 2016-07, Vol.106 (4), p.598-612

2016

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Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction

Medicinal research reviews, 2016-09, Vol.36 (5), p.789-844

2016

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CHIP promotes autophagy‐mediated degradation of aggregating mutant p53 in hypoxic conditions

The FEBS journal, 2018-09, Vol.285 (17), p.3197-3214

2018

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Tuning the Binding Affinity and Selectivity of Perfluoroaryl‐Stapled Peptides by Cysteine‐Editing

Chemistry : a European journal, 2019-01, Vol.25 (1), p.177-182

2019

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Chemical cross‐linking and native mass spectrometry: A fruitful combination for structural biology

Protein science, 2015-08, Vol.24 (8), p.1193-1209

2015

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Probing the Small-Molecule Inhibition of an Anticancer Therapeutic Protein-Protein Interaction Using a Solid-State Nanopore

Angewandte Chemie International Edition, 2016-05, Vol.55 (19), p.5713-5717

International ed. in English, 2016

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Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

EMBO reports, 2009-11, Vol.10 (11), p.1250-1258

2009

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Probing theα-Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis

Chemical biology & drug design, 2010-04, Vol.75 (4), p.348-359

2010

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Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript

FEBS letters, 2010-11, Vol.584 (21), p.4463-4468

2010

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Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain

Cancer science, 2020-02, Vol.111 (2), p.451-466

2020

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An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein-Protein Interactions

Angewandte Chemie International Edition, 2016-09, Vol.55 (37), p.11096-11100

2016

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Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions

Angewandte Chemie International Edition, 2020-03, Vol.59 (13), p.5235-5241

International ed. in English, 2020

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Small‐molecule stabilization of the p53 – 14‐3‐3 protein‐protein interaction

FEBS letters, 2017-08, Vol.591 (16), p.2449-2457

2017

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SirT3 and p53 Deacetylation in Aging and Cancer

Journal of cellular physiology, 2017-09, Vol.232 (9), p.2308-2311

2017

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How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures

ChemMedChem, 2016-04, Vol.11 (8), p.757-772

2016

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Generation and Characterization of Site‐Specifically Mono‐Ubiquitylated p53

Chembiochem : a European journal of chemical biology, 2022-03, Vol.23 (6), p.e202100659-n/a

2022

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Multifunctional Compounds for Activation of the p53‐Y220C Mutant in Cancer

Chemistry : a European journal, 2018-12, Vol.24 (67), p.17734-17742

2018

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Dynamic perspectives into the mechanisms of mutation‐induced p53‐DNA binding loss and inactivation using active perturbation theory: Structural and molecular insights toward the design of potent reactivators in cancer therapy

Journal of cellular biochemistry, 2019-01, Vol.120 (1), p.951-966

2019

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Different Oligomeric States of the Tumor Suppressor p53 Show Identical Binding Behavior towards the S100β Homodimer

Chembiochem : a European journal of chemical biology, 2022-06, Vol.23 (11), p.e202100665-n/a

2022

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TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data

Discoveries and controversies in BCL‐2 protein‐mediated apoptosis

Tumor suppressive role for kinases phosphorylating p53 in DNA damage‐induced apoptosis

iSEE: Interface structure, evolution, and energy‐based machine learning predictor of binding affinity changes upon mutations

EZH2 cooperates with gain‐of‐function p53 mutants to promote cancer growth and metastasis

Regulation of cellular senescence via the FOXO4‐p53 axis

Tetramer formation of tumor suppressor protein p53: Structure, function, and applications

Medicinal Chemistry Strategies to Disrupt the p53-MDM2/MDMX Interaction

CHIP promotes autophagy‐mediated degradation of aggregating mutant p53 in hypoxic conditions

Tuning the Binding Affinity and Selectivity of Perfluoroaryl‐Stapled Peptides by Cysteine‐Editing

Chemical cross‐linking and native mass spectrometry: A fruitful combination for structural biology

Probing the Small-Molecule Inhibition of an Anticancer Therapeutic Protein-Protein Interaction Using a Solid-State Nanopore

Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

Probing theα-Helical Structural Stability of Stapled p53 Peptides: Molecular Dynamics Simulations and Analysis

Δ160p53 is a novel N-terminal p53 isoform encoded by Δ133p53 transcript

Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain

An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein-Protein Interactions

Multicomponent Peptide Stapling as a Diversity‐Driven Tool for the Development of Inhibitors of Protein–Protein Interactions

Small‐molecule stabilization of the p53 – 14‐3‐3 protein‐protein interaction

SirT3 and p53 Deacetylation in Aging and Cancer

How To Design a Successful p53-MDM2/X Interaction Inhibitor: A Thorough Overview Based on Crystal Structures

Generation and Characterization of Site‐Specifically Mono‐Ubiquitylated p53

Multifunctional Compounds for Activation of the p53‐Y220C Mutant in Cancer

Dynamic perspectives into the mechanisms of mutation‐induced p53‐DNA binding loss and inactivation using active perturbation theory: Structural and molecular insights toward the design of potent reactivators in cancer therapy

Different Oligomeric States of the Tumor Suppressor p53 Show Identical Binding Behavior towards the S100β Homodimer

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