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The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet

Cellular and molecular life sciences : CMLS, 2021-03, Vol.78 (6), p.3045-3055

2021

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Photoperiod- and Triiodothyronine-dependent Regulation of Reproductive Neuropeptides, Proinflammatory Cytokines, and Peripheral Physiology in Siberian Hamsters (Phodopus sungorus)

Journal of biological rhythms, 2016-06, Vol.31 (3), p.299-307

2016

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Neuronal human BACE1 knockin induces systemic diabetes in mice

Diabetologia, 2016-07, Vol.59 (7), p.1513-1523

2016

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Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes

Nature communications, 2024-05, Vol.15 (1), p.3690-3690, Article 3690

2024

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Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

Diabetes (New York, N.Y.), 2009-03, Vol.58 (3), p.590-599

2009

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Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

Angiogenesis (London), 2021-08, Vol.24 (3), p.567-581

2021

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In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues

Biochemical and biophysical research communications, 2010-10, Vol.401 (1), p.104-111

2010

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Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dependent Mechanism

Diabetes (New York, N.Y.), 2014-02, Vol.63 (2), p.456-470

2014

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Protein tyrosine phosphatase 1B in metabolic diseases and drug development

Nature reviews. Endocrinology, 2024-06, Vol.20 (6), p.366-378

2024

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Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B

Molecular and Cellular Biology, 2007-11, Vol.27 (21), p.7727-7734

2007

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Executive functions predict conceptual learning of science

British journal of developmental psychology, 2016-06, Vol.34 (2), p.261-275

2016

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Microparticles from patients with metabolic syndrome induce vascular hypo-reactivity via Fas/Fas-ligand pathway in mice

PloS one, 2011-11, Vol.6 (11), p.e27809-e27809

2011

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Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues

Molecular and Cellular Biology, 2009-08, Vol.29 (16), p.4563-4573

2009

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Preclinical evaluation of tissue-selective gene therapies for congenital generalised lipodystrophy

Gene therapy, 2024-09, Vol.31 (9-10), p.445-454

2024

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Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Cancer research (Chicago, Ill.), 2018-01, Vol.78 (1), p.75-87

2018

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Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR -/- mice

Scientific reports, 2023-03, Vol.13 (1), p.3937-16, Article 3937

2023

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Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress

Biochemical journal, 2011-09, Vol.438 (2), p.369-378

2011

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Ablation of Bscl2 /seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Disease models & mechanisms, 2020-01, Vol.13 (1)

2020

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Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

Scientific reports, 2018-12, Vol.8 (1), p.17863-11, Article 17863

2018

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Disruption of the Striated Muscle Glycogen Targeting Subunit PPP1R3A of Protein Phosphatase 1 Leads to Increased Weight Gain, Fat Deposition, and Development of Insulin Resistance

Diabetes (New York, N.Y.), 2003-03, Vol.52 (3), p.596-604

2003

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Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Scientific reports, 2017-03, Vol.7 (1), p.43782, Article 43782

2017

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Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

Molecular metabolism (Germany), 2018-04, Vol.10, p.55-65

2018

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Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice

Scientific reports, 2017-08, Vol.7 (1), p.9977-10, Article 9977

2017

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Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21

Aging cell, 2014-10, Vol.13 (5), p.817-827

2014

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Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

Biochemical pharmacology, 2016-01, Vol.100, p.86-97

2016

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The anxiety and ethanol intake controlling GAL5.1 enhancer is epigenetically modulated by, and controls preference for, high-fat diet

Photoperiod- and Triiodothyronine-dependent Regulation of Reproductive Neuropeptides, Proinflammatory Cytokines, and Peripheral Physiology in Siberian Hamsters (Phodopus sungorus)

Neuronal human BACE1 knockin induces systemic diabetes in mice

Comparison of intramyocellular lipid metabolism in patients with diabetes and male athletes

Liver-Specific Deletion of Protein-Tyrosine Phosphatase 1B (PTP1B) Improves Metabolic Syndrome and Attenuates Diet-Induced Endoplasmic Reticulum Stress

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

In vivo differential effects of fasting, re-feeding, insulin and insulin stimulation time course on insulin signaling pathway components in peripheral tissues

Myeloid-Cell Protein Tyrosine Phosphatase-1B Deficiency in Mice Protects Against High-Fat Diet and Lipopolysaccharide-Induced Inflammation, Hyperinsulinemia, and Endotoxemia Through an IL-10 STAT3-Dependent Mechanism

Protein tyrosine phosphatase 1B in metabolic diseases and drug development

Improved Glucose Homeostasis in Mice with Muscle-Specific Deletion of Protein-Tyrosine Phosphatase 1B

Executive functions predict conceptual learning of science

Microparticles from patients with metabolic syndrome induce vascular hypo-reactivity via Fas/Fas-ligand pathway in mice

Neuronal Protein Tyrosine Phosphatase 1B Deficiency Results in Inhibition of Hypothalamic AMPK and Isoform-Specific Activation of AMPK in Peripheral Tissues

Preclinical evaluation of tissue-selective gene therapies for congenital generalised lipodystrophy

Deficiency in Protein Tyrosine Phosphatase PTP1B Shortens Lifespan and Leads to Development of Acute Leukemia

Fenretinide inhibits obesity and fatty liver disease but induces Smpd3 to increase serum ceramides and worsen atherosclerosis in LDLR -/- mice

Liver-specific deletion of protein tyrosine phosphatase (PTP) 1B improves obesity- and pharmacologically induced endoplasmic reticulum stress

Ablation of Bscl2 /seipin in hepatocytes does not cause metabolic dysfunction in congenital generalised lipodystrophy

Female adipose tissue-specific Bscl2 knockout mice develop only moderate metabolic dysfunction when housed at thermoneutrality and fed a high-fat diet

Disruption of the Striated Muscle Glycogen Targeting Subunit PPP1R3A of Protein Phosphatase 1 Leads to Increased Weight Gain, Fat Deposition, and Development of Insulin Resistance

Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice

Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease

Direct comparison of methionine restriction with leucine restriction on the metabolic health of C57BL/6J mice

Methionine restriction restores a younger metabolic phenotype in adult mice with alterations in fibroblast growth factor 21

Fenretinide mediated retinoic acid receptor signalling and inhibition of ceramide biosynthesis regulates adipogenesis, lipid accumulation, mitochondrial function and nutrient stress signalling in adipocytes and adipose tissue

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