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The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity

International journal of molecular sciences, 2016-10, Vol.17 (10), p.1714-1714

2016

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Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

The AAPS journal, 2017-11, Vol.20 (1), p.4-4, Article 4

2017

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3D human liver spheroids for translational pharmacology and toxicology

Basic & clinical pharmacology & toxicology, 2022-01, Vol.130 (S1), p.5-15

2022

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Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

Toxicological sciences, 2018-06, Vol.163 (2), p.655-665

2018

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Human hepatic 3D spheroids as a model for steatosis and insulin resistance

Scientific reports, 2018-09, Vol.8 (1), p.14297-12, Article 14297

2018

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Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

Cell, 2018-02, Vol.172 (5), p.1079-1090.e12

2018

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In vitro and ex vivo models of adipocytes

American Journal of Physiology: Cell Physiology, 2021-05, Vol.320 (5), p.C822-C841

2021

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Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection

EMBO molecular medicine, 2021-01, Vol.13 (1), p.e13426-n/a

2021

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Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

Genetics in medicine, 2018-06, Vol.20 (6), p.622-629

2018

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Comprehensive overview of the pharmacogenetic diversity in Ashkenazi Jews

Journal of medical genetics, 2018-09, Vol.55 (9), p.617-627

2018

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Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury

Frontiers in pharmacology, 2019-09, Vol.10, p.1093

2019

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Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data

Frontiers in pharmacology, 2018-12, Vol.9, p.1437-1437

2018

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In vitro and ex vivo modeling of enteric bacterial infections

Gut microbes, 2023, Vol.15 (1), p.2158034-2158034

2023

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Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Hepatology (Baltimore, Md.), 2016-11, Vol.64 (5), p.1743-1756

2016

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Intraocular liver spheroids for non-invasive high-resolution in vivo monitoring of liver cell function

Nature communications, 2024-01, Vol.15 (1), p.767-767, Article 767

2024

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Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk [S]

Journal of lipid research, 2018-10, Vol.59 (10), p.1987-2000

2018

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Rare genetic variant burden in DPYD predicts severe fluoropyrimidine-related toxicity risk

Biomedicine & pharmacotherapy, 2022-10, Vol.154, p.113644-113644, Article 113644

2022

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OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Scientific reports, 2024-07, Vol.14 (1), p.17334-13, Article 17334

2024

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Emerging trends in pharmacogenomics: from common variant associations toward comprehensive genomic profiling

Human genomics, 2023-11, Vol.17 (1), p.1-105, Article 105

2023

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Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain

Genes & development, 2021-08, Vol.35 (15-16), p.1190-1207

2021

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Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response

Journal of clinical medicine, 2020-01, Vol.9 (1), p.286

2020

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Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain

Cell reports (Cambridge), 2020-06, Vol.31 (9), p.107699-107699, Article 107699

2020

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Editorial: Population Pharmacogenomics (PGx): From Variant Identification to Clinical Implementation

Frontiers in genetics, 2021-08, Vol.12, p.736626-736626

2021

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The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders

Npj genomic medicine, 2021-06, Vol.6 (1), p.41-41, Article 41

2021

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The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib-induced liver injury: implications for ferroptosis

Cell death & disease, 2024-08, Vol.15 (8), p.600-17

2024

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The Importance of Patient-Specific Factors for Hepatic Drug Response and Toxicity

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

3D human liver spheroids for translational pharmacology and toxicology

Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions

Human hepatic 3D spheroids as a model for steatosis and insulin resistance

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation

In vitro and ex vivo models of adipocytes

Human soluble ACE2 improves the effect of remdesivir in SARS‐CoV‐2 infection

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

Comprehensive overview of the pharmacogenetic diversity in Ashkenazi Jews

Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury

Computational Methods for the Pharmacogenetic Interpretation of Next Generation Sequencing Data

In vitro and ex vivo modeling of enteric bacterial infections

Massive rearrangements of cellular MicroRNA signatures are key drivers of hepatocyte dedifferentiation

Intraocular liver spheroids for non-invasive high-resolution in vivo monitoring of liver cell function

Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk [S]

Rare genetic variant burden in DPYD predicts severe fluoropyrimidine-related toxicity risk

OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Emerging trends in pharmacogenomics: from common variant associations toward comprehensive genomic profiling

Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain

Genetic and Epigenetic Biomarkers of Immune Checkpoint Blockade Response

Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain

Editorial: Population Pharmacogenomics (PGx): From Variant Identification to Clinical Implementation

The prevalence, genetic complexity and population-specific founder effects of human autosomal recessive disorders

The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib-induced liver injury: implications for ferroptosis

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