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Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR

Cell research, 2021-05, Vol.31 (5), p.569-579

2021

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Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level

Scientific reports, 2016-09, Vol.6 (1), p.33233-33233, Article 33233

2016

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Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (47), p.12046-12050

2018

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Structure-guided development of heterodimer-selective GPCR ligands

Nature communications, 2016-07, Vol.7 (1), p.12298-12298, Article 12298

2016

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Hybridization of β‑Adrenergic Agonists and Antagonists Confers G Protein Bias

Journal of medicinal chemistry, 2019-05, Vol.62 (10), p.5111-5131

2019

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Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-04, Vol.14 (1), p.2138-2138, Article 2138

2023

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Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-05, Vol.14 (1), p.2992-2992, Article 2992

2023

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Presynaptic vesicular accumulation is required for antipsychotic efficacy in psychotic-like rats

Journal of psychopharmacology (Oxford), 2021-01, Vol.35 (1), p.65-77

2021

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Is the functional response of a receptor determined by the thermodynamics of ligand binding?

Biophysical journal, 2024-02, Vol.123 (3), p.472a-472a

2024

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Structure‐Based Evolution of G Protein‐Biased μ‐Opioid Receptor Agonists

Angewandte Chemie (International ed.), 2022-06, Vol.61 (26), p.e202200269-n/a

International ed. in English, 2022

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Is the Functional Response of a Receptor Determined by the Thermodynamics of Ligand Binding?

Journal of chemical theory and computation, 2023-11, Vol.19 (22), p.8414-8422

2023

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Potent haloperidol derivatives covalently binding to the dopamine D2 receptor

Bioorganic & medicinal chemistry, 2017-10, Vol.25 (19), p.5084-5094

2017

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Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3

Angewandte Chemie (International ed.), 2016-12, Vol.55 (49), p.15277-15281

International ed. in English, 2016

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Basal Histamine H4 Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif

Chemistry : a European journal, 2019-11, Vol.25 (64), p.14613-14624

2019

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Regiospecific Introduction of Halogens on the 2‑Aminobiphenyl Subunit Leading to Highly Potent and Selective M3 Muscarinic Acetylcholine Receptor Antagonists and Weak Inverse Agonists

Journal of medicinal chemistry, 2020-04, Vol.63 (8), p.4349-4369

2020

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Discovery of Novel Nonpeptidic PAR2 Ligands

ACS medicinal chemistry letters, 2020-06, Vol.11 (6), p.1316-1323

2020

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Strukturbasierte Entwicklung von G‐Protein bevorzugenden μ‐Opioidrezeptor Agonisten

Angewandte Chemie, 2022-06, Vol.134 (26), p.n/a

2022

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Author Correction: Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-05, Vol.14 (1), p.2992

2023

Volltextzugriff (PDF)

Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Nature communications, 2023-04, Vol.14 (1), p.2138

2023

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Binding pathway determines norepinephrine selectivity for the human β 1 AR over β 2 AR

Cell research, 2021-05, Vol.31 (5), p.569

2021

Volltextzugriff (PDF)

Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3

Angewandte Chemie, 2016-12, Vol.128 (49), p.15503-15507

2016

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Modeling Cell-Cell Interactions in Parkinson's Disease Using Human Stem Cell-Based Models

Frontiers in cellular neuroscience, 2020-01, Vol.13, p.571-571

2020

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Efficient and Easy Conversion of Human iPSCs into Functional Induced Microglia-like Cells

International journal of molecular sciences, 2022-04, Vol.23 (9), p.4526

2022

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MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis

Brain (London, England : 1878), 2020-01, Vol.143 (1), p.55-68

2020

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Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR

Visualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level

Structure-guided development of selective M3 muscarinic acetylcholine receptor antagonists

Structure-guided development of heterodimer-selective GPCR ligands

Hybridization of β‑Adrenergic Agonists and Antagonists Confers G Protein Bias

Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Author Correction: Constrained catecholamines gain β2AR selectivity through allosteric effects on pocket dynamics

Presynaptic vesicular accumulation is required for antipsychotic efficacy in psychotic-like rats

Is the functional response of a receptor determined by the thermodynamics of ligand binding?

Structure‐Based Evolution of G Protein‐Biased μ‐Opioid Receptor Agonists

Is the Functional Response of a Receptor Determined by the Thermodynamics of Ligand Binding?

Potent haloperidol derivatives covalently binding to the dopamine D2 receptor

Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3

Basal Histamine H4 Receptor Activation: Agonist Mimicry by the Diphenylalanine Motif

Regiospecific Introduction of Halogens on the 2‑Aminobiphenyl Subunit Leading to Highly Potent and Selective M3 Muscarinic Acetylcholine Receptor Antagonists and Weak Inverse Agonists

Discovery of Novel Nonpeptidic PAR2 Ligands

Strukturbasierte Entwicklung von G‐Protein bevorzugenden μ‐Opioidrezeptor Agonisten

Author Correction: Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Constrained catecholamines gain β 2 AR selectivity through allosteric effects on pocket dynamics

Binding pathway determines norepinephrine selectivity for the human β 1 AR over β 2 AR

Identification of Two Distinct Sites for Antagonist and Biased Agonist Binding to the Human Chemokine Receptor CXCR3

Modeling Cell-Cell Interactions in Parkinson's Disease Using Human Stem Cell-Based Models

Efficient and Easy Conversion of Human iPSCs into Functional Induced Microglia-like Cells

Gene replacement therapy with onasemnogene abeparvovec in children with spinal muscular atrophy aged 24 months or younger and bodyweight up to 15 kg: an observational cohort study

MN1 C-terminal truncation syndrome is a novel neurodevelopmental and craniofacial disorder with partial rhombencephalosynapsis

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