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DNA-encoded chemistry: enabling the deeper sampling of chemical space

Nature reviews. Drug discovery, 2017-02, Vol.16 (2), p.131-147

2017

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Rethinking drug design in the artificial intelligence era

Nature reviews. Drug discovery, 2020-05, Vol.19 (5), p.353-364

2020

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Reality check: lipid-oligonucleotide conjugates for therapeutic applications

Expert opinion on drug discovery, 2023-02, Vol.18 (2), p.129-134

Goodnow, Robert A

2023

Volltextzugriff (PDF)

A handbook for DNA-encoded chemistry: theory and applications for exploring chemical space and drug discovery

Goodnow, Robert A

1, 2014

Volltextzugriff (PDF)

DNA Compatible Multistep Synthesis and Applications to DNA Encoded Libraries

Bioconjugate chemistry, 2015-08, Vol.26 (8), p.1623-1632

2015

Volltextzugriff (PDF)

Platform Technologies in Drug Discovery and Validation

Goodnow, Robert A

1, 2017

Volltextzugriff (PDF)

DNA-Encoded Library Technology (DELT) After a Quarter Century

SLAS discovery, 2018-06, Vol.23 (5), p.385-386

Goodnow, Robert

2018

Volltextzugriff (PDF)

Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis

MedChemComm, 2016-01, Vol.7 (7), p.1316-1322, Article 1316

2016

Volltextzugriff (PDF)

2015 First Boston Symposium of Encoded Library Platforms

MedChemComm, 2016-07, Vol.7 (7), p.1268-127

2016

Volltextzugriff (PDF)

Efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007-02, Vol.846 (1), p.291-297

2007

Volltextzugriff (PDF)

Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2

ChemMedChem, 2017-06, Vol.12 (12), p.917-924

2017

Volltextzugriff (PDF)

Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries

Journal of medicinal chemistry, 2002-01, Vol.45 (1), p.137-142

2002

Volltextzugriff (PDF)

Leukotriene B4 receptor antagonists as therapeutics for inflammatory disease: preclinical and clinical developments

Expert opinion on investigational drugs, 2007-12, Vol.16 (12), p.1909-1920

2007

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Exploration of liquid and supercritical fluid chromatographic chiral separation and purification of Nutlin-3—A small molecule antagonist of MDM2

Journal of pharmaceutical and biomedical analysis, 2007-12, Vol.45 (5), p.720-729

2007

Volltextzugriff (PDF)

Efficient Synthesis of Aryl Methyl Sulfide Derivatives Using (Methylthio)trimethylsilane as Methylthiolation Reagent

Synthetic communications, 2010-11, Vol.40 (24), p.3691-3698

2010

Volltextzugriff (PDF)

Cover Picture: Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2 (ChemMedChem 12/2017)

ChemMedChem, 2017-06, Vol.12 (12), p.860-860

2017

Volltextzugriff (PDF)

Hit and lead identification: Integrated technology-based approaches

Drug discovery today. Technologies, 2006-12, Vol.3 (4), p.367-375

Goodnow, Robert A.

2006

Volltextzugriff (PDF)

An improved model for fragment-based lead generation at AstraZeneca

Drug discovery today, 2016-08, Vol.21 (8), p.1272-1283

2016

Volltextzugriff (PDF)

Stereochemical Control Factors in the Hantzsch Thiazole Synthesis: A Hammett Substitution Correlation Analysis

Organic letters, 2001-11, Vol.3 (23), p.3655-3658

2001

Volltextzugriff (PDF)

Glycosylation on the Merrifield Resin Using Anomeric Sulfoxides

Journal of the American Chemical Society, 1994-07, Vol.116 (15), p.6953-6954

1994

Volltextzugriff (PDF)

Fragment-based Differential Targeting of PPI Stabilizer Interfaces

Journal of medicinal chemistry, 2020-07, Vol.63 (13), p.6694-6707

2020

Volltextzugriff (PDF)

Lead generation: reality check on commonly held views

Expert opinion on drug discovery, 2008-07, Vol.3 (7), p.733-744

2008

Volltextzugriff (PDF)

Current practices in generation of small molecule new leads

Journal of cellular biochemistry, 2001, Vol.84 (S37), p.13-21

Goodnow Jr, Robert A.

2001

Volltextzugriff (PDF)

Hit and Lead Identification: Efficient Practices for Drug Discovery

Progress in Medicinal Chemistry, 2007, Vol.45, p.1-61

2007

Volltextzugriff (PDF)

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DNA-encoded chemistry: enabling the deeper sampling of chemical space

Rethinking drug design in the artificial intelligence era

Reality check: lipid-oligonucleotide conjugates for therapeutic applications

A handbook for DNA-encoded chemistry: theory and applications for exploring chemical space and drug discovery

DNA Compatible Multistep Synthesis and Applications to DNA Encoded Libraries

Platform Technologies in Drug Discovery and Validation

DNA-Encoded Library Technology (DELT) After a Quarter Century

Development and design of the tertiary amino effect reaction for DNA-encoded library synthesis

2015 First Boston Symposium of Encoded Library Platforms

Efficient and scalable method in isolation of polymethoxyflavones from orange peel extract by supercritical fluid chromatography

Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2

Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries

Leukotriene B4 receptor antagonists as therapeutics for inflammatory disease: preclinical and clinical developments

Exploration of liquid and supercritical fluid chromatographic chiral separation and purification of Nutlin-3—A small molecule antagonist of MDM2

Efficient Synthesis of Aryl Methyl Sulfide Derivatives Using (Methylthio)trimethylsilane as Methylthiolation Reagent

Cover Picture: Target Deconvolution Efforts on Wnt Pathway Screen Reveal Dual Modulation of Oxidative Phosphorylation and SERCA2 (ChemMedChem 12/2017)

Discovery of Novel and Potent Leukotriene B4 Receptor Antagonists. Part 1

Hit and lead identification: Integrated technology-based approaches

An improved model for fragment-based lead generation at AstraZeneca

Stereochemical Control Factors in the Hantzsch Thiazole Synthesis: A Hammett Substitution Correlation Analysis

Glycosylation on the Merrifield Resin Using Anomeric Sulfoxides

Fragment-based Differential Targeting of PPI Stabilizer Interfaces

Lead generation: reality check on commonly held views

Current practices in generation of small molecule new leads

Hit and Lead Identification: Efficient Practices for Drug Discovery

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