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Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15240-15245

2010

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Characterization of substrate binding and catalysis in the potential antibacterial target N‐acetylglucosamine‐1‐phosphate uridyltransferase (GlmU)

Protein science, 2007-12, Vol.16 (12), p.2657-2666

2007

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The structure of a redundant enzyme: a second isoform of aspartate β-semialdehyde dehydrogenase in Vibrio cholerae

Acta crystallographica. Section D, Biological crystallography., 2008-03, Vol.64 (3), p.321-330

2008

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A New Branch in the Family: Structure of Aspartate-β-semialdehyde Dehydrogenase from Methanococcus jannaschii

Journal of molecular biology, 2005-11, Vol.353 (5), p.1055-1068

2005

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4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase

Journal of medicinal chemistry, 2007-10, Vol.50 (21), p.5090-5102

2007

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Synthesis and evaluation of novel α-heteroaryl-phenylpropanoic acid derivatives as PPARα/γ dual agonists

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7113-7125

2009

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Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARα/γ dual agonists, and X-ray crystallographic studies

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (9), p.4883-4907

2008

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Inhibitors of Bcr-abl... breaking new ground again

Nature chemical biology, 2006-02, Vol.2 (2), p.63-64

2006

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Structural asymmetry and intersubunit communication in muscle creatine kinase

Acta crystallographica. Section D, Biological crystallography., 2007-03, Vol.63 (3), p.381-389

2007

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A New Branch in the Family: Structure of Aspartate-[beta]-semialdehyde Dehydrogenase from Methanococcus jannaschii

Journal of molecular biology, 2010-07, Vol.353 ((5) ; 2005)

2010

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Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-[gamma]

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.767-772

2013

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Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-[gamma]

Journal of medicinal chemistry, 2013-03, Vol.54 ((12) ; 06, 2011)

2013

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Synthesis and evaluation of novel [alpha]-heteroaryl-phenylpropanoic acid derivatives as PPAR[alpha/gamma] dual agonists

Bioorganic & medicinal chemistry letters, 2010-09, Vol.17 ((20) ; 10, 2009)

2010

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Central Modulation of Circadian Rhythm via CK1 Inhibition for Psychiatric Indications

Annual Reports in Medicinal Chemistry, 2011, Vol.46, p.33-51

2011

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Structural and functional studies of aspartate β-semialdehyde dehydrogenase, aspartokinase and creatine kinase

Ohren, Jeffrey F

2007

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Erratum: Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Nature structural & molecular biology, 2005-03, Vol.12 (3), p.278-278

2005

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Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Nature structural & molecular biology, 2005-03, Vol.12 (3), p.278-278

2005

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Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7113-7125

2009

Volltextzugriff (PDF)

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (9), p.4883-4907

2008

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The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme

Biochemistry (Easton), 2006-02, Vol.45 (6), p.1712-1722

2006

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Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Characterization of substrate binding and catalysis in the potential antibacterial target N‐acetylglucosamine‐1‐phosphate uridyltransferase (GlmU)

Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning

The structure of a redundant enzyme: a second isoform of aspartate β-semialdehyde dehydrogenase in Vibrio cholerae

A New Branch in the Family: Structure of Aspartate-β-semialdehyde Dehydrogenase from Methanococcus jannaschii

4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase

Synthesis and evaluation of novel α-heteroaryl-phenylpropanoic acid derivatives as PPARα/γ dual agonists

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARα/γ dual agonists, and X-ray crystallographic studies

Inhibitors of Bcr-abl... breaking new ground again

Structural asymmetry and intersubunit communication in muscle creatine kinase

A New Branch in the Family: Structure of Aspartate-[beta]-semialdehyde Dehydrogenase from Methanococcus jannaschii

Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-[gamma]

Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-[gamma]

Synthesis and evaluation of novel [alpha]-heteroaryl-phenylpropanoic acid derivatives as PPAR[alpha/gamma] dual agonists

Central Modulation of Circadian Rhythm via CK1 Inhibition for Psychiatric Indications

Structural and functional studies of aspartate β-semialdehyde dehydrogenase, aspartokinase and creatine kinase

Erratum: Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARalpha/gamma dual agonists, and X-ray crystallographic studies

The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme

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