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Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primates

Neuropsychopharmacology (New York, N.Y.), 2014-11, Vol.39 (12), p.2742-2749

2014

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Characterization of a CNS penetrant, selective M 1 muscarinic receptor agonist, 77‐LH‐28‐1

British journal of pharmacology, 2008-07, Vol.154 (5), p.1104-1115

2008

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Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with positron emission tomography

Synapse (New York, N.Y.), 2010-07, Vol.64 (7), p.542-549

2010

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Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1

British journal of pharmacology, 2008-07, Vol.154 (5), p.1104-1115

2008

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[ 11C]GSK931145: A new pet ligand for glycine transporter 1

NeuroImage (Orlando, Fla.), 2008, Vol.41, p.T21-T21

2008

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Forearm rotation alters interosseous ligament strain distribution

The Journal of hand surgery (American ed.), 2000-11, Vol.25 (6), p.1058-1063

2000

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Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.285-290

1999

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Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures

British journal of pharmacology, 1997-08, Vol.121 (8), p.1679-1686

1997

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Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4537-4539

1996

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Use of the radioligand [ 125I]-SB-217644 in the characterisation and solubilisation of the novel binding site for the anticonvulsant SB-204269 in rat brain membranes and cell lines

Neuropharmacology, 2000-09, Vol.39 (12), p.2457-2463

2000

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Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

British journal of pharmacology, 1997-08, Vol.121 (8), p.1687-1691

1997

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Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2903-2906

1998

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Characterisation of the binding of [3H]‐SB‐674042, a novel nonpeptide antagonist, to the human orexin‐1 receptor

British journal of pharmacology, 2004-01, Vol.141 (2), p.340-346

2004

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Solubilisation of A Novel Anticonvulsant Binding Site From Pig Cortical Membranes

Journal of receptors and signal transduction, 2000, Vol.20 (2-3), p.167-186

2000

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Probing the Molecular Mechanism of Interaction between 4- n -Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M 1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist

Molecular pharmacology, 2006-01, Vol.69 (1), p.236-246

2006

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Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols

Bioorganic & medicinal chemistry letters, 1997-06, Vol.7 (12), p.1573-1576

1997

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Meeting Highlights: 17th Annual Meeting of the European Neuroscience Association 4-8 September, 1994, Vienna, Austria

Expert opinion on investigational drugs, 1994-12, Vol.3 (12), p.1331-1332

Herdon, H

1994

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SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia

Neuropharmacology, 1993-11, Vol.32 (11), p.1249-1257

1993

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α- and β-adrenergic binding sites in sheep cerebral cortex: Characterisation, effects of photoperiod and treatment with estrogen/progesterone

Brain research bulletin, 1983, Vol.10 (1), p.159-161

1983

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Diethylstilbestrol regulates the number of α- and β-adrenergic binding sites in incubated hypothalamus and amygdala

Brain research, 1982-09, Vol.248 (1), p.79-85

1982

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Cloning, functional characterisation and population analysis of a variant form of the human glycine type 2 transporter

FEBS letters, 1999-12, Vol.463 (3), p.301-306

1999

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Differences between the release of radiolabelled and endogenous dopamine from superfused rat brain slices: Effects of depolarizing stimuli, amphetamine and synthesis inhibition

Brain research, 1985-12, Vol.348 (2), p.309-320

1985

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Characterization of a CNS penetrant, selective M sub(1) muscarinic receptor agonist, 77-LH-28-1

British journal of pharmacology, 2008-07, Vol.154 (5), p.1104-1115

2008

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The novel anticonvulsant SB 204269 binds to a stereospecific site in the mouse brain

European journal of pharmacology, 1996-10, Vol.314 (3), p.R7-R8

1996

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Investigations of the roles of dihydropyridine and ω-conotoxin-sensitive calcium channels in mediating depolarisation-evoked endogenous dopamine release from striatal slices

Naunyn-Schmiedeberg's archives of pharmacology, 1989-07, Vol.340 (1), p.36-40

1989

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Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primates

Characterization of a CNS penetrant, selective M 1 muscarinic receptor agonist, 77‐LH‐28‐1

Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with positron emission tomography

Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1

[ 11C]GSK931145: A new pet ligand for glycine transporter 1

Forearm rotation alters interosseous ligament strain distribution

Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures

Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Use of the radioligand [ 125I]-SB-217644 in the characterisation and solubilisation of the novel binding site for the anticonvulsant SB-204269 in rat brain membranes and cell lines

Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Characterisation of the binding of [3H]‐SB‐674042, a novel nonpeptide antagonist, to the human orexin‐1 receptor

Solubilisation of A Novel Anticonvulsant Binding Site From Pig Cortical Membranes

Probing the Molecular Mechanism of Interaction between 4- n -Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M 1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist

Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols

Meeting Highlights: 17th Annual Meeting of the European Neuroscience Association 4-8 September, 1994, Vienna, Austria

SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia

α- and β-adrenergic binding sites in sheep cerebral cortex: Characterisation, effects of photoperiod and treatment with estrogen/progesterone

Diethylstilbestrol regulates the number of α- and β-adrenergic binding sites in incubated hypothalamus and amygdala

Cloning, functional characterisation and population analysis of a variant form of the human glycine type 2 transporter

Differences between the release of radiolabelled and endogenous dopamine from superfused rat brain slices: Effects of depolarizing stimuli, amphetamine and synthesis inhibition

Characterization of a CNS penetrant, selective M sub(1) muscarinic receptor agonist, 77-LH-28-1

The novel anticonvulsant SB 204269 binds to a stereospecific site in the mouse brain

Investigations of the roles of dihydropyridine and ω-conotoxin-sensitive calcium channels in mediating depolarisation-evoked endogenous dopamine release from striatal slices

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