UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 33

Sortiert nach

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (34), p.15240-15245

2010

Volltextzugriff (PDF)

Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors

Biochemical journal, 2014-06, Vol.460 (2), p.211-222

2014

Volltextzugriff (PDF)

Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-γ

Journal of medicinal chemistry, 2011-06, Vol.54 (12), p.4219-4233

2011

Volltextzugriff (PDF)

Characterization of substrate binding and catalysis in the potential antibacterial target N‐acetylglucosamine‐1‐phosphate uridyltransferase (GlmU)

Protein science, 2007-12, Vol.16 (12), p.2657-2666

2007

Volltextzugriff (PDF)

The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme

Biochemistry (Easton), 2006-02, Vol.45 (6), p.1712-1722

2006

Volltextzugriff (PDF)

A New Branch in the Family: Structure of Aspartate-β-semialdehyde Dehydrogenase from Methanococcus jannaschii

Journal of molecular biology, 2005-11, Vol.353 (5), p.1055-1068

2005

Volltextzugriff (PDF)

Phosphopantetheine Adenylyltransferase from Escherichia coli: Investigation of the Kinetic Mechanism and Role in Regulation of Coenzyme A Biosynthesis

Journal of Bacteriology, 2007-11, Vol.189 (22), p.8196-8205

2007

Volltextzugriff (PDF)

4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase

Journal of medicinal chemistry, 2007-10, Vol.50 (21), p.5090-5102

2007

Volltextzugriff (PDF)

Synthesis and evaluation of novel α-heteroaryl-phenylpropanoic acid derivatives as PPARα/γ dual agonists

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7113-7125

2009

Volltextzugriff (PDF)

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARα/γ dual agonists, and X-ray crystallographic studies

Bioorganic & medicinal chemistry, 2008-05, Vol.16 (9), p.4883-4907

2008

Volltextzugriff (PDF)

The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment

Recent results in cancer research, 2007, Vol.172, p.155

2007

Volltextzugriff (PDF)

Inhibitors of Bcr-abl... breaking new ground again

Nature chemical biology, 2006-02, Vol.2 (2), p.63-64

2006

Volltextzugriff (PDF)

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases

Bioorganic & medicinal chemistry letters, 2006-05, Vol.16 (9), p.2337-2340

2006

Volltextzugriff (PDF)

Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period

The Journal of pharmacology and experimental therapeutics, 2009-08, Vol.330 (2), p.430

2009

Volltextzugriff (PDF)

A New Branch in the Family: Structure of Aspartate-[beta]-semialdehyde Dehydrogenase from Methanococcus jannaschii

Journal of molecular biology, 2010-07, Vol.353 ((5) ; 2005)

2010

Volltextzugriff (PDF)

2-Alkylamino-and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)

Bioorganic & medicinal chemistry, 2008-12, Vol.18 (23), p.6171-6174

2008

Volltextzugriff (PDF)

Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-[gamma]

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.767-772

2013

Volltextzugriff (PDF)

Beyond the MEK-pocket: Can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

Bioorganic & medicinal chemistry letters, 2009-01, Vol.19 (1), p.226-229

2009

Volltextzugriff (PDF)

Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-[gamma]

Journal of medicinal chemistry, 2013-03, Vol.54 ((12) ; 06, 2011)

2013

Volltextzugriff (PDF)

Synthesis and evaluation of novel [alpha]-heteroaryl-phenylpropanoic acid derivatives as PPAR[alpha/gamma] dual agonists

Bioorganic & medicinal chemistry letters, 2010-09, Vol.17 ((20) ; 10, 2009)

2010

Volltextzugriff (PDF)

Erratum to “2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles— O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)” [Bioorg. Med. Chem. Lett. 18 (2008) 6171]

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3695-3695

2009

Volltextzugriff (PDF)

Central Modulation of Circadian Rhythm via CK1 Inhibition for Psychiatric Indications

Annual Reports in Medicinal Chemistry, 2011, Vol.46, p.33-51

2011

Volltextzugriff (PDF)

Structural and functional studies of aspartate β-semialdehyde dehydrogenase, aspartokinase and creatine kinase

Ohren, Jeffrey F

2007

Volltextzugriff (PDF)

Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Nature structural & molecular biology, 2005-03, Vol.12 (3), p.278-278

2005

Volltextzugriff (PDF)

1 – 25 von 33

Suche als RSS-Feed

Aktive Filter

ThemaBiophysics

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(31)
Mit Volltextzugriff
(29)

Publikationsform

Sprache

Englisch
(33)
Japanisch
(4)

Erscheinungsjahr

n.n

Thema

Science & Technology
(20)
Life Sciences & Biomedicine
(19)
Pharmacology & Pharmacy
(13)
Chemistry, Medicinal
(12)
Animals
(11)
Humans
(9)
Biological And Medical Sciences
(8)
Chemistry
(8)
Chemistry, Organic
(8)
Crystallography, X-Ray
(8)
Models, Molecular
(8)
Physical Sciences
(8)
Biochemistry & Molecular Biology
(7)
Medical Sciences
(7)
Mice
(7)
Pharmacology. Drug Treatments
(7)
Protein Kinase Inhibitors - Pharmacology
(7)
Structure-Activity Relationship
(7)
Rats
(6)
Basic Biological Sciences
(5)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

Selectively targeting an inactive conformation of interleukin-2-inducible T-cell kinase by allosteric inhibitors

Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-γ

Aminopyrazole Carboxamide Bruton’s Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning

Characterization of substrate binding and catalysis in the potential antibacterial target N‐acetylglucosamine‐1‐phosphate uridyltransferase (GlmU)

The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme

A New Branch in the Family: Structure of Aspartate-β-semialdehyde Dehydrogenase from Methanococcus jannaschii

Phosphopantetheine Adenylyltransferase from Escherichia coli: Investigation of the Kinetic Mechanism and Role in Regulation of Coenzyme A Biosynthesis

4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase

Synthesis and evaluation of novel α-heteroaryl-phenylpropanoic acid derivatives as PPARα/γ dual agonists

Effects of modifications of the linker in a series of phenylpropanoic acid derivatives: Synthesis, evaluation as PPARα/γ dual agonists, and X-ray crystallographic studies

The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment

Inhibitors of Bcr-abl... breaking new ground again

The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases

Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period

A New Branch in the Family: Structure of Aspartate-[beta]-semialdehyde Dehydrogenase from Methanococcus jannaschii

2-Alkylamino-and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)

Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-[gamma]

Beyond the MEK-pocket: Can current MEK kinase inhibitors be utilized to synthesize novel type III NCKIs? Does the MEK-pocket exist in kinases other than MEK?

Discovery of a Series of Imidazo[4,5-b]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-[gamma]

Synthesis and evaluation of novel [alpha]-heteroaryl-phenylpropanoic acid derivatives as PPAR[alpha/gamma] dual agonists

Erratum to “2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles— O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)” [Bioorg. Med. Chem. Lett. 18 (2008) 6171]

Central Modulation of Circadian Rhythm via CK1 Inhibition for Psychiatric Indications

Structural and functional studies of aspartate β-semialdehyde dehydrogenase, aspartokinase and creatine kinase

Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

Aktive Filter

Suchergebnisse filtern