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Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

Immunity (Cambridge, Mass.), 2012-09, Vol.37 (3), p.412-425

2012

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Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

Nature (London), 2021-05, Vol.593 (7857), p.130-135

2021

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Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

Journal of Virology, 2011-08, Vol.85 (15), p.7788-7796

2011

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Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants

Nature (London), 2021-07, Vol.595 (7866), p.278-282

2021

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Broad and potent neutralization of HIV―1 by a gp41―specific human antibody

Nature (London), 2012-11, Vol.491 (7424), p.406-412

2012

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Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield

Structure (London), 2017-10, Vol.25 (10), p.1631-1639.e2

2017

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Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (15), p.5663-5668

2012

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Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262

Proteins, structure, function, and bioinformatics, 2015-03, Vol.83 (3), p.590-596

2015

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Structural basis of respiratory syncytial virus neutralization by motavizumab

Nature structural & molecular biology, 2010-02, Vol.17 (2), p.248-250

2010

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Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

Nature structural & molecular biology, 2016-09, Vol.23 (9), p.811-820

2016

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Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

Molecular cell, 2010-03, Vol.37 (5), p.656-667

2010

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Structural definition of a conserved neutralization epitope on HIV-1 gp120

Nature, 2007-02, Vol.445 (7129), p.732-737

2007

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Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth

Cell reports (Cambridge), 2018-10, Vol.25 (4), p.893-908.e7

2018

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Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability

Journal of Virology, 2011-07, Vol.85 (13), p.6687-6701

2011

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Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection

Journal of virology, 2014-11, Vol.88 (21), p.12895-12906

2014

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Improvement of antibody functionality by structure-guided paratope engraftment

Nature communications, 2019-02, Vol.10 (1), p.721-721, Article 721

2019

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PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4

Journal of Virology, 2012-04, Vol.86 (8), p.4394-4403

2012

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Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

Journal of Virology, 2010-12, Vol.84 (23), p.12236-12244

2010

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Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate

Journal of Virology, 2012-01, Vol.86 (1), p.284-292

2012

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Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors

Journal of medicinal chemistry, 2012-05, Vol.55 (9), p.4382-4396

2012

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The Mannose-Dependent Epitope for Neutralizing Antibody 2G12 on Human Immunodeficiency Virus Type 1 Glycoprotein gp120

Journal of Virology, 2002-07, Vol.76 (14), p.7293-7305

2002

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Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7

Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

Nanobodies from camelid mice and llamas neutralize SARS-CoV-2 variants

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Broad and potent neutralization of HIV―1 by a gp41―specific human antibody

Microsecond Dynamics and Network Analysis of the HIV-1 SOSIP Env Trimer Reveal Collective Behavior and Conserved Microdomains of the Glycan Shield

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies

Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops

Crystal structure of a fully glycosylated HIV-1 gp120 core reveals a stabilizing role for the glycan at Asn262

Structural basis of respiratory syncytial virus neutralization by motavizumab

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV

Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies

Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth

Crystal Structures of GII.10 and GII.12 Norovirus Protruding Domains in Complex with Histo-Blood Group Antigens Reveal Details for a Potential Site of Vulnerability

Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection

Improvement of antibody functionality by structure-guided paratope engraftment

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

PGV04, an HIV-1 gp120 CD4 Binding Site Antibody, Is Broad and Potent in Neutralization but Does Not Induce Conformational Changes Characteristic of CD4

Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

Structural Basis for Norovirus Inhibition and Fucose Mimicry by Citrate

Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors

The Mannose-Dependent Epitope for Neutralizing Antibody 2G12 on Human Immunodeficiency Virus Type 1 Glycoprotein gp120

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