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Progress towards drug discovery for Friedreich’s Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein

Bioorganic & medicinal chemistry, 2020-06, Vol.28 (11), p.115472-115472, Article 115472

2020

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Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2850-2855

2018

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Clinical status of duplex RNA

Bioorganic & medicinal chemistry letters, 2010-06, Vol.20 (11), p.3203-3207

2010

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Visible Light Photocatalysis in Organic Chemistry

1, 2018

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Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat

Biochemistry (Easton), 2010-11, Vol.49 (47), p.10166-10178

2010

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Predicting potential miRNA target sites within gene promoters

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (14), p.3791-3794

2009

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Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates

ACS omega, 2023-11, Vol.8 (45), p.42797-42802

2023

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Biodistribution of phosphodiester and phosphorothioate siRNA

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1139-1143

2004

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Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs

Biological chemistry, 2011-04, Vol.392 (4), p.315-325

2011

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Antisense and Antigene Inhibition of Gene Expression by Cell-Permeable Oligonucleotide–Oligospermine Conjugates

Journal of the American Chemical Society, 2011-06, Vol.133 (22), p.8404-8407

2011

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Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5202-5205

2011

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Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis- o-(aminoethoxy)phenyl]pyrrolocytosine

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6181-6184

2009

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48000-fold Acceleration of Hybridization by Chemically Modified Oligonucleotides

Journal of the American Chemical Society, 1995-09, Vol.117 (36), p.9373-9374

Corey, David R

1995

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Inhibition of telomerase by BIBR 1532 and related analogues

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (7), p.1333-1336

2003

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Toward Synthetic Transcription Activators: Recruitment of Transcription Factors to DNA by a PNA-Peptide Chimera

Journal of the American Chemical Society, 2002-03, Vol.124 (9), p.1838-1839

2002

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Rules for Strand Invasion by Chemically Modified Oligonucleotides

Journal of the American Chemical Society, 1999-03, Vol.121 (10), p.2012-2020

1999

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Liver cell specific targeting of peptide nucleic acid oligomers

Bioorganic & medicinal chemistry letters, 2001-05, Vol.11 (10), p.1269-1272

2001

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Radiolytic Gas Production from Aluminum Coupons (Alloy 1100 and 6061) in Helium Environments—Assessing the Extended Storage of Aluminum Clad Spent Nuclear Fuel

Materials, 2022-10, Vol.15 (20), p.7317

2022

Volltextzugriff (PDF)

Engineering Orthogonal Ligand−Receptor Pairs from “Near Drugs”

Journal of the American Chemical Society, 2001-11, Vol.123 (46), p.11367-11371

2001

Volltextzugriff (PDF)

An investigation into the minimum requirements for peptide hydrolysis by mutation of the catalytic triad of trypsin

Journal of the American Chemical Society, 1992-02, Vol.114 (5), p.1784-1790

1992

Volltextzugriff (PDF)

Telomerase: An Unusual Target for Cytotoxic Agents

Chemical research in toxicology, 2000-10, Vol.13 (10), p.957-960

Corey, David R

2000

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Synthesis and membrane permeability of PNA-peptide conjugates

Bioorganic & medicinal chemistry letters, 1997-12, Vol.7 (23), p.3001-3006

1997

Volltextzugriff (PDF)

Radiochemical Studies Using Nuclear Magnetic Resonance

Pilgrim, Corey David

2018

Volltextzugriff (PDF)

Specific and nonspecific inhibition of transcription by DNA, PNA, and phosphorothioate promoter analog duplexes

Bioorganic & medicinal chemistry letters, 1996-12, Vol.6 (23), p.2897-2900

1996

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Sequence-selective hydrolysis of duplex DNA by an oligonucleotide-directed nuclease

Journal of the American Chemical Society, 1989-10, Vol.111 (22), p.8523-8525

1989

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Progress towards drug discovery for Friedreich’s Ataxia: Identifying synthetic oligonucleotides that more potently activate expression of human frataxin protein

Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion

Clinical status of duplex RNA

Visible Light Photocatalysis in Organic Chemistry

Allele-Selective Inhibition of Mutant Huntingtin Expression with Antisense Oligonucleotides Targeting the Expanded CAG Repeat

Predicting potential miRNA target sites within gene promoters

Targeting the Expanded TCF4/Fuchs’ Endothelial Corneal Dystrophy CUG Repeat with Morpholino Peptide Conjugates

Biodistribution of phosphodiester and phosphorothioate siRNA

Allele-selective inhibition of ataxin-3 (ATX3) expression by antisense oligomers and duplex RNAs

Antisense and Antigene Inhibition of Gene Expression by Cell-Permeable Oligonucleotide–Oligospermine Conjugates

Clonal Rett Syndrome cell lines to test compounds for activation of wild-type MeCP2 expression

Cellular localization and allele-selective inhibition of mutant huntingtin protein by peptide nucleic acid oligomers containing the fluorescent nucleobase [bis- o-(aminoethoxy)phenyl]pyrrolocytosine

48000-fold Acceleration of Hybridization by Chemically Modified Oligonucleotides

Inhibition of telomerase by BIBR 1532 and related analogues

Toward Synthetic Transcription Activators: Recruitment of Transcription Factors to DNA by a PNA-Peptide Chimera

Rules for Strand Invasion by Chemically Modified Oligonucleotides

Liver cell specific targeting of peptide nucleic acid oligomers

Radiolytic Gas Production from Aluminum Coupons (Alloy 1100 and 6061) in Helium Environments—Assessing the Extended Storage of Aluminum Clad Spent Nuclear Fuel

Engineering Orthogonal Ligand−Receptor Pairs from “Near Drugs”

An investigation into the minimum requirements for peptide hydrolysis by mutation of the catalytic triad of trypsin

Telomerase: An Unusual Target for Cytotoxic Agents

Synthesis and membrane permeability of PNA-peptide conjugates

Radiochemical Studies Using Nuclear Magnetic Resonance

Specific and nonspecific inhibition of transcription by DNA, PNA, and phosphorothioate promoter analog duplexes

Sequence-selective hydrolysis of duplex DNA by an oligonucleotide-directed nuclease

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