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Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

Nature communications, 2022-12, Vol.13 (1), p.7428-14, Article 7428

2022

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How Do Short Chain Nonionic Detergents Destabilize G‑Protein-Coupled Receptors?

Journal of the American Chemical Society, 2016-11, Vol.138 (47), p.15425-15433

2016

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Structure and dynamics of a constitutively active neurotensin receptor

Scientific reports, 2016-12, Vol.6 (1), p.38564-38564, Article 38564

2016

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Structural Dynamics and Thermostabilization of Neurotensin Receptor 1

The journal of physical chemistry. B, 2015-04, Vol.119 (15), p.4917-4928

2015

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Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis

Cell death & disease, 2018-03, Vol.9 (3), p.401-21, Article 401

2018

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Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A2A Receptor

Structure (London), 2019-04, Vol.27 (4), p.703-712.e3

2019

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Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors

Journal of chemical theory and computation, 2014-11, Vol.10 (11), p.5149-5160

2014

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Higher glucagon-to-insulin ratio is associated with elevated glycated hemoglobin levels in type 2 diabetes patients

The Korean Journal of Internal Medicine, 2019, 34(5), , pp.1068-1077

2019

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Dynamic Behavior of the Active and Inactive States of the Adenosine A2A Receptor

The journal of physical chemistry. B, 2014-03, Vol.118 (12), p.3355-3365

2014

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Activation Microswitches in Adenosine Receptor A2A Function as Rheostats in the Cell Membrane

Biochemistry (Easton), 2020-10, Vol.59 (42), p.4059-4071

2020

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A femtosecond pulse fiber laser at 1935 nm using a bulk-structured Bi2Te3 topological insulator

Optics express, 2014-04, Vol.22 (7), p.7865-7874

2014

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Activation Microswitches in Adenosine Receptor A2AFunction as Rheostats in Cell Membrane

Biophysical journal, 2021-02, Vol.120 (3), p.131a-131a

2021

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Activation Microswitches in Adenosine Receptor A 2A Function as Rheostats in the Cell Membrane

Biochemistry (Easton), 2020-10, Vol.59 (42), p.4059-4071

2020

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How Do Branched Detergents Stabilize GPCRs in Micelles?

Biochemistry (Easton), 2020-06, Vol.59 (23), p.2125-2134

2020

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Pharmacophore Models of Paclitaxel- and Epothilone-Based Microtubule Stabilizing Agents

Bulletin of the Korean Chemical Society, 2013, 34(7), , pp.1972-1984

2013

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Biased agonists differentially modulate the receptor conformation ensembles in Angiotensin II type 1 receptor

Journal of molecular graphics & modelling, 2023-01, Vol.118, p.108365-108365, Article 108365

2023

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Discovery of novel potassium-competitive acid blockers: Protonated form of ligand-receptor complex system

Biophysical journal, 2023-02, Vol.122 (3), p.134a-135a

2023

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Selective probes and antagonists for G protein-coupled receptor LPAR1

Biophysical journal, 2023-02, Vol.122 (3), p.134a-134a

2023

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Mode-locked pulse generation from an all-fiberized, Tm-Ho-codoped fiber laser incorporating a graphene oxide-deposited side-polished fiber

Optics express, 2013-08, Vol.21 (17), p.20062-20072

2013

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Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A 2A Receptor

Structure (London), 2019-04, Vol.27 (4), p.703

2019

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Conserved Mechanism of Conformational Stability and Dynamics in G‑Protein-Coupled Receptors

Journal of chemical theory and computation, 2016-11, Vol.12 (11), p.5575-5584

2016

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Structural insights into the subtype-selective antagonist binding to the M 2 muscarinic receptor

Nature chemical biology, 2018-12, Vol.14 (12), p.1150

2018

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Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors

Molecular pharmacology, 2018-04, Vol.93 (4), p.288-296

2018

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Dynamic Behaviors of Various Conformational States of A2A Receptor

Biophysical journal, 2018-02, Vol.114 (3), p.240a-240a

2018

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Distinct Dynamics of Biased Agonists Bound AT1R

Biophysical journal, 2018-02, Vol.114 (3), p.239a-239a

2018

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Dynamic spatiotemporal determinants modulate GPCR:G protein coupling selectivity and promiscuity

How Do Short Chain Nonionic Detergents Destabilize G‑Protein-Coupled Receptors?

Structure and dynamics of a constitutively active neurotensin receptor

Structural Dynamics and Thermostabilization of Neurotensin Receptor 1

Kaempferol targeting on the fibroblast growth factor receptor 3-ribosomal S6 kinase 2 signaling axis prevents the development of rheumatoid arthritis

Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A2A Receptor

Rapid Computational Prediction of Thermostabilizing Mutations for G Protein-Coupled Receptors

Higher glucagon-to-insulin ratio is associated with elevated glycated hemoglobin levels in type 2 diabetes patients

Dynamic Behavior of the Active and Inactive States of the Adenosine A2A Receptor

Activation Microswitches in Adenosine Receptor A2A Function as Rheostats in the Cell Membrane

A femtosecond pulse fiber laser at 1935 nm using a bulk-structured Bi2Te3 topological insulator

Activation Microswitches in Adenosine Receptor A2AFunction as Rheostats in Cell Membrane

Activation Microswitches in Adenosine Receptor A 2A Function as Rheostats in the Cell Membrane

How Do Branched Detergents Stabilize GPCRs in Micelles?

Pharmacophore Models of Paclitaxel- and Epothilone-Based Microtubule Stabilizing Agents

Biased agonists differentially modulate the receptor conformation ensembles in Angiotensin II type 1 receptor

Discovery of novel potassium-competitive acid blockers: Protonated form of ligand-receptor complex system

Selective probes and antagonists for G protein-coupled receptor LPAR1

Mode-locked pulse generation from an all-fiberized, Tm-Ho-codoped fiber laser incorporating a graphene oxide-deposited side-polished fiber

Dynamic Role of the G Protein in Stabilizing the Active State of the Adenosine A 2A Receptor

Conserved Mechanism of Conformational Stability and Dynamics in G‑Protein-Coupled Receptors

Structural insights into the subtype-selective antagonist binding to the M 2 muscarinic receptor

Identifying Functional Hotspot Residues for Biased Ligand Design in G-Protein-Coupled Receptors

Dynamic Behaviors of Various Conformational States of A2A Receptor

Distinct Dynamics of Biased Agonists Bound AT1R

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